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Keywords: Prolactin
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Journal Articles
Neuroendocrinology 1–12.
Published Online: 03 December 2024
... that explore the effects of thyroid status modulation on other hormonal axes remain scarce. We aimed to determine the effects of thyroid status modulation on prolactin, IGF-1, cortisol, LH, testosterone, and SHBG levels. We also explored whether effects differed depending on type of challenge, sex...
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Journal Articles
Neuroendocrinology (2022) 112 (9): 856–873.
Published Online: 30 August 2022
...Hai Duc Nguyen; Hojin Oh; Byung Pal Yu; Ngoc Minh Hong Hoang; Won Hee Jo; Hae Young Chung; Min-Sun Kim Background: Converging evidence indicates prolactin (PRL) and diabetes play an important role in the pathophysiology of cognitive impairment. However, little is known about the mechanisms...
Journal Articles
Neuroendocrinology (2021) 111 (9): 805–830.
Published Online: 24 August 2021
..., using a novel variant of the pup retrieval paradigm, the motivated pup retrieval test. We also analyse the role of prolactin (PRL) and of stimuli derived from a litter of pups and its mother, in the acquisition of maternal motivation. Experimental design included female mice in 3 conditions: lactating...
Journal Articles
Neuroendocrinology (2022) 112 (3): 276–286.
Published Online: 26 April 2021
..., instructions or products referred to in the content or advertisements. Adenohypophyseal tumours Biomarker Growth hormone Magnetic resonance imaging Non-functioning gonadotropinoma Pituitary tumours Prolactin Relative SI ratios, adjusted to the SI within each patient’s normal-appearing white...
Journal Articles
Neuroendocrinology (2019) 109 (1): 7–19.
Published Online: 20 March 2019
... and prolactinomas. Up to 40% of macroprolactinemic patients may present with hypogonadism symptoms, infertility, and/or galactorrhea. Thus, the screening for macroprolactin is indicated not only for asymptomatic subjects but also for those without an obvious cause for their prolactin (PRL) elevation. Before...
Journal Articles
Neuroendocrinology (2019) 109 (1): 42–50.
Published Online: 18 March 2019
...-resistant prolactinomas includes several options. Any BRC-resistant patient should be switched to CAB which will normalize prolactin in 80% of patients. As long as adverse effects do not develop, dose escalation of CAB is reasonable, with the expectation that subsequent dose reduction will be possible...
Journal Articles
Neuroendocrinology (2019) 108 (2): 84–97.
Published Online: 07 March 2019
... and signaling pathways that control lactotrope cell turnover is needed in order to encourage new therapeutic developments. We have previously shown that prolactin (PRL) acts as a proapoptotic and antiproliferative factor on lactotropes, maintaining anterior pituitary cell homeostasis, which contrasts...
Journal Articles
Neuroendocrinology (2019) 109 (1): 51–56.
Published Online: 07 November 2018
...Ilan Shimon Prolactin-secreting adenomas (prolactinomas) are the most common secreting adenomas of the pituitary. Microprolactinomas (diameter <10 mm) are frequently diagnosed in women, whereas macroprolactinomas (maximum diameter ≥10 mm) are generally seen in men. Most macroprolactinomas...
Journal Articles
Neuroendocrinology (2018) 107 (2): 105–113.
Published Online: 16 April 2018
...Ali Abbara; Sophie A. Clarke; Alexander Nesbitt; Sabreen Ali; Alexander N. Comninos; Emma Hatfield; Niamh M. Martin; Amir H. Sam; Karim Meeran; Waljit S. Dhillo Background/Aims: Hyperprolactinaemia is a common cause of amenorrhoea due to hypogonadotropic hypogonadism. Prolactin is hypothesised...
Journal Articles
Neuroendocrinology (2018) 106 (4): 324–334.
Published Online: 27 August 2017
... prolactin (PRL). We determined whether oxytocin (OT), which stimulates PRL secretion acting directly on anterior pituitary lactotrophs, mediates the stimulatory action of Mp and NAL on PRL secretion during late pregnancy. Methods: On day 19 of pregnancy, circulating and pituitary OT and PRL levels were...
Journal Articles
Neuroendocrinology (2016) 103 (5): 605–615.
Published Online: 30 October 2015
..., in order to protect the organism against misfolded proteins. In this study, we analysed the effect of HSF1 deficiency on core body temperature regulation. Materials and Methods: Body temperature, locomotor activity, and food consumption of wild-type mice and HSF1-deficient mice were recorded. Prolactin...
Journal Articles
Neuroendocrinology (2015) 102 (4): 288–299.
Published Online: 29 May 2015
.... Similar to Nrg1α, Nrg1β increased the prolactin (PRL) expression in rat pituitary RC-4B/C cells, which can be inhibited by an Akt inhibitor. In addition, Nrg1β had no apparent effect on growth hormone expression at the mRNA or protein levels. Collectively, we conclude that hypothalamic Nrg1 may...
Journal Articles
Journal Articles
Neuroendocrinology (2014) 98 (4): 299–310.
Published Online: 17 December 2013
... patients with prolactinomas (13 men, 48 women, 41 with microadenoma, 20 with macroadenoma), aged 34.4 ± 10.3 years, entered the study. In all patients, prolactin (PRL) and metabolic parameters were assessed at diagnosis and after 12 and 60 months of continuous CAB treatment. MetS was diagnosed according...
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Neuroendocrinology (2012) 95 (4): 332–343.
Published Online: 21 March 2012
...Sunmin Park; Suna Kang; Hye-Won Lee; Byoung Seob Ko Background: Prolactin secretion is self-regulating as it acts upon hypothalamic dopaminergic systems which inhibit prolactin release from the anterior pitutary. Circulating prolactin improves glucose homeostasis by increasing insulin action...
Journal Articles
Neuroendocrinology (2012) 95 (4): 325–331.
Published Online: 07 February 2012
... men, 23.6 ± 5.0 years and BMI 22.6 ± 1.9 kg/m 2 , were included. Serotonergic responsivity was assessed using the prolactin response to infusion with citalopram, a selective serotonin reuptake inhibitor, which is a validated tool to assess serotonergic tone. All participants received a lipid/heparin...
Journal Articles