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1-20 of 30
Keywords: Prognosis
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Journal Articles
Impact of Sex and Deprivation on Neuroendocrine Tumour Survival: Challenges of Heterogeneous Data
Open AccessAilbhe Lawlor, Harriet Wylde, Marie Line El Asmar, Benjamin Easton White, John Ramage, Mieke Van Hemelrijck, Beth Russell
Journal:
Neuroendocrinology
Neuroendocrinology (2025)
Published Online: 29 April 2025
..., such as sex and deprivation, may play a role in who survives a NET diagnosis. This systematic review identifies the available evidence assessing the impact of sex and deprivation on the prognosis of patients diagnosed with NETs. Summary: Using protocol-driven search terms, Embase and Ovid were searched...
Journal Articles
Gender Perspective in Lung Neuroendocrine Tumors: A Critical Review
Available to Purchase
Journal:
Neuroendocrinology
Neuroendocrinology (2025)
Published Online: 24 April 2025
..., functioning syndromes, prognosis, and response/toxicity to treatments in L-NETs according to sex. Results: Female patients are more likely to have an L-NET than males. The reasons underlying these gender differences are still unclear; a biologic mechanism for the sex difference is possible, through a role...
Journal Articles
Survivin as a Therapeutic Target for Neuroendocrine Neoplasms
Available to PurchaseYuma Hane, Takahiro Tsuchikawa, Toru Nakamura, Kanako C. Hatanaka, Katsunori Sasaki, Noriko Kawai, Shintaro Takeuchi, Kimitaka Tanaka, Yoshitsugu Nakanishi, Toshimichi Asano, Takehiro Noji, Toshiaki Shichinohe, Yutaka Hatanaka, Yoshihiko Hirohshi, Toshihiko Torigoe, Satoshi Hirano
Journal:
Neuroendocrinology
Neuroendocrinology (2025) 115 (3-4): 295–307.
Published Online: 02 January 2025
...: Although neuroendocrine neoplasms (NENs) have a good prognosis, distant metastasis remains a crucial prognostic factor. Survivin, a tumor-associated antigen, is overexpressed in several solid tumors, indicating poor prognosis. We aimed to evaluate the clinical significance and role of survivin...
Journal Articles
Systemic Cancer Hallmarks as Novel Markers Associated with Progression-Free Survival in Gastroenteropancreatic Neuroendocrine Tumor Patients Undergoing Peptide Receptor Radionuclide Therapy
Available to PurchaseMahesh Kumar Padwal, Rahul Vithalrao Parghane, Avik Chakraborty, Aman Kumar Ujaoney, Narasimha Anaganti, Sandip Basu, Bhakti Basu
Journal:
Neuroendocrinology
Neuroendocrinology 1–14.
Published Online: 03 December 2024
... tumors Peptide receptor radionuclide therapy Peripheral blood RNA-Seq Cancer hallmarks Prognosis Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) arise from the diffused neuroendocrine system located along the gastrointestinal tract and in the pancreas [ 1, 2 ]. These typically...
Journal Articles
Prognosis of Patients with Bronchopulmonary Neuroendocrine Neoplasms in a Tertiary Neuroendocrine Tumor Centre of Excellence
Available to PurchaseKarina Stubkjær Rewitz, Henning Grønbæk, Elizaveta Mitkina Tabaksblat, Simon Mark Dahl Baunwall, Gitte Dam
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (12): 1214–1224.
Published Online: 07 June 2022
.../previous smokers ( p = 0.51). In the follow-up period, only 2 (9%) of the 22 recurrences were found on a routine bronchoscopy. Both of these recurrences were also found by diagnostic imaging. Conclusions: Surgical treatment, especially, and diagnosis of TC were associated with a good prognosis. Furthermore...
Journal Articles
High Mast Cell Density Predicts a Favorable Prognosis in Patients with Pancreatic Neuroendocrine Neoplasms
Open Access
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (9): 845–855.
Published Online: 28 December 2021
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mast cell Pancreatic neuroendocrine neoplasm Tumor-infiltrating immune cells Tumor microenvironment Prognosis Pancreatic neuroendocrine neoplasms (PanNENs) are a group...
Journal Articles
Cell-Free DNA and Clinical Characteristics in Patients with Small Intestinal or Pancreatic Neuroendocrine Tumors
Available to PurchaseStine Karlsen Oversoe, Boe Sandahl Sorensen, Elizaveta Mitkina Tabaksblat, Henning Gronbaek, Jens Kelsen
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (1): 43–50.
Published Online: 18 January 2021
... in current smokers ( p = 0.029). Discussion/Conclusion: cfDNA levels are higher in NET patients than in healthy controls; however, there was no association with prognosis, and cfDNA levels were unaffected by PRRT. Our observations suggest that cfDNA levels are not associated with the disease course in low...
Journal Articles
Tumor Growth Rate to Predict the Outcome of Patients with Neuroendocrine Tumors: Performance and Sources of Variability
Available to PurchaseClarisse Dromain, Anders Sundin, Pavan Najran, Hector Vidal Trueba, Marco Dioguardi Burgio, Joakim Crona, Marta Opalinska, Luciana Carvalho, Regis Franca, Philip Borg, Naik Vietti Violi, Niklaus Schaefer, Carlos Lopez, Daniela Pezzutti, Louis de Mestier, Angela Lamarca, Frederico Costa, Marianne Pavel, Maxime Ronot
Journal:
Neuroendocrinology
Neuroendocrinology (2021) 111 (9): 831–839.
Published Online: 27 July 2020
.... Neuroendocrine tumors Prognosis Biomarkers Reproducibility of results Neuroendocrine tumors (NETs) represent a very heterogeneous group of neoplasms that arise from the diffuse endocrine system. The primary tumor may be located in many different organ systems, most frequently in the lungs bronchi...
Journal Articles
Elderly Patients with Metastatic Neuroendocrine Tumors Are Undertreated and Have Shorter Survival: The LyREMeNET Study
Available to PurchaseAnnie Lemelin, Delphine Maucort-Boulch, Elisabeth Castel-Kremer, Julien Forestier, Valérie Hervieu, Marianne Lorcet, Florent Boutitie, Aurélie Theillaumas, Philip Robinson, Antoine Duclos, Catherine Lombard-Bohas, Thomas Walter
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (7-8): 653–661.
Published Online: 14 July 2020
..., instructions or products referred to in the content or advertisements. 2019 Neuroendocrine tumor Metastatic neuroendocrine tumor Elderly Prognosis Treatment Neuroendocrine tumors (NETs) are rare and include a heterogeneous group of neoplasms derived from the gastrointestinal tract...
Journal Articles
Neuroendocrine Tumor Omic Gene Cluster Analysis Amplifies the Prognostic Accuracy of the NETest
Available to Purchase
Journal:
Neuroendocrinology
Neuroendocrinology (2021) 111 (5): 490–504.
Published Online: 11 May 2020
..., instructions or products referred to in the content or advertisements. Biomarkers Carcinoid Ki-67 NETest Neuroendocrine neoplasia Neuroendocrine tumors Prognosis Progression Neuroendocrine tumors (NETs) represent a diverse and heterogeneous group of neoplastic lesions with widely different...
Journal Articles
Proposal of a Panel of Genes Identified by miRNA Profiling as Candidate Prognostic Biomarkers in Lung Carcinoids
Available to PurchaseIda Rapa, Arianna Votta, Jessica Giorcelli, Stefania Izzo, Angelica Rigutto, Jasna Metovic, Francesca Napoli, Marco Volante
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 111 (1-2): 115–122.
Published Online: 11 February 2020
... carcinoids. [email protected] 26 08 2019 9 02 2020 11 2 2020 Lung Carcinoid Biomarker KLF12 Prognosis 2020 S. Karger AG, Basel 2020 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...
Journal Articles
High Metabolic Tumour Volume on 18-Fluorodeoxyglucose Positron Emission Tomography Predicts Poor Survival from Neuroendocrine Neoplasms
Available to PurchaseDavid L. Chan, Elizabeth J. Bernard, Geoffrey Schembri, Paul J. Roach, Meaghan Johnson, Nick Pavlakis, Stephen Clarke, Dale L. Bailey
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (11-12): 950–958.
Published Online: 12 November 2019
... was significant on UV ( p < 0.00001) but not MV ( p = 0.76). Tumours of higher grade had higher MTV (mean MTV – G1: 39.6 mL, G2: 107 mL, G3: 337 mL; p = 0.0001 by ANOVA). Conclusions: Quantitative analysis of 18 F-FDG PET in NEN is feasible. High MTV/TLG are predictors of poor prognosis in NEN. Further...
Journal Articles
High-Grade Progression Confers Poor Survival in Pancreatic Neuroendocrine Tumors
Available to PurchaseJohan Botling, Angela Lamarca, Duska Bajic, Olov Norlén, Vincent Lönngren, Josefine Kjaer, Barbro Eriksson, Staffan Welin, Per Hellman, Guido Rindi, Britt Skogseid, Joakim Crona
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (11-12): 891–898.
Published Online: 29 October 2019
... a more aggressive biology correlate with prognosis. The purpose of this study was to characterize changes in PanNET differentiation and proliferation over time and to correlate findings to overall survival (OS). Patients and Methods: In this retrospective cohort study, we screened 475 PanNET patients...
Journal Articles
Post-Radiation Grade 3 Neuroendocrine Carcinoma: A New Entity?
Available to PurchaseJulien Hadoux, Pierre Blanchard, Jean-Yves Scoazec, Pascal Burtin, David Planchard, David Malka, Amandine Berdelou, Valérie Boige, Pierre Duvillard, Sophie Leboulleux, Matthieu Faron, Lambros Tselikas, Eric Deutsch, Michel Ducreux, Eric Baudin
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 111 (1-2): 139–145.
Published Online: 22 October 2019
... Prognosis Second cancer Radiation therapy is an important part of the therapeutic arsenal against cancer with up to 50% of cancer patients receiving radiation therapy as part of their treatment [ 1 ]. Although radiation therapy has allowed increasing overall survival and local control in patients...
Journal Articles
Capecitabine and Temozolomide in Patients with Advanced Pulmonary Carcinoid Tumours
Available to PurchaseGeorge Papaxoinis, Zoe Kordatou, Lynne McCallum, Magdy Nasralla, Angela Lamarca, Alison Backen, Daisuke Nonaka, Wasat Mansoor
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (5): 413–421.
Published Online: 23 August 2019
... make up approximately 75% of the cases and have an excellent prognosis, with a 5-year survival rate approximately 90%, while ACs represent 25% of the cases and have a worse prognosis, with a 5-year survival rate between 40 and 70% [ 1 ]. Around 20% of patients with AC present with advanced disease...
Journal Articles
Blood Chromogranin A Is Not Effective as a Biomarker for Diagnosis or Management of Bronchopulmonary Neuroendocrine Tumors/Neoplasms
Available to PurchaseSomer Matar, Anna Malczewska, Kjell Oberg, Lisa Bodei, Harry Aslanian, Anna Lewczuk-Myślicka, Pier Luigi Filosso, Alejandro L. Suarez, Agnieszka Kolasińska-Ćwikła, Matteo Roffinella, Beata Kos-Kudła, Jarosław B. Ćwikła, Ignat A. Drozdov, Mark Kidd, Irvin M. Modlin
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (3-4): 185–197.
Published Online: 16 April 2019
.... Bronchopulmonary Lung Chromogranin A Biomarker Carcinoid Diagnosis Prognosis Cancer biomarkers are essential for the identification of disease and as tools to quantify disease progression (PD) and outcome. Numerous types of biomarkers have been proposed and studied [ 1 ]. Among these, dysregulated...
Journal Articles
Prognostic Evaluations Tailored to Specific Gastric Neuroendocrine Neoplasms: Analysis Of 200 Cases with Extended Follow-Up
Available to PurchaseAlessandro Vanoli, Stefano La Rosa, Emanuela Miceli, Catherine Klersy, Roberta Maragliano, Francesca Capuano, Andrea Persichella, Michele Martino, Frediano Inzani, Ombretta Luinetti, Antonio Di Sabatino, Fausto Sessa, Marco Paulli, Gino Roberto Corazza, Guido Rindi, Cesare Bordi, Carlo Capella, Enrico Solcia
Journal:
Neuroendocrinology
Neuroendocrinology (2018) 107 (2): 114–126.
Published Online: 12 June 2018
... with intermediate prognosis, and various rare tumor types. Histologic differentiation, proliferative grade, size, level of gastric wall invasion, and local or distant metastases are used as prognostic markers. However, their value remains to be tailored to specific gastric NENs. Methods: Series of type I NETs ( n...
Journal Articles
Bone Metastases in Patients with Neuroendocrine Neoplasm: Frequency and Clinical, Therapeutic, and Prognostic Relevance
Available to Purchase
Journal:
Neuroendocrinology
Neuroendocrinology (2017) 106 (1): 30–37.
Published Online: 01 January 2018
... Therapy Prognosis Based on the local database of the ENETS center of the University of Marburg, Germany, 677 patients treated at the hospital between January 1, 2000 and June 1, 2015 were identified for inclusion in this retrospective study. 327 of these 677 patients presented with distant...
Journal Articles
Digestive System Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms
Available to PurchaseLouis de Mestier, Jérôme Cros, Cindy Neuzillet, Olivia Hentic, Axel Egal, Nelly Muller, Olivier Bouché, Guillaume Cadiot, Philippe Ruszniewski, Anne Couvelard, Pascal Hammel
Journal:
Neuroendocrinology
Neuroendocrinology (2017) 105 (4): 412–425.
Published Online: 12 August 2017
... malignancies depending on the metastatic potential of the tumour components. High-grade malignant component should be considered even if it represents <30% of the tumour. The prognosis of MiNEN is generally intermediate between those of the two “pure” components composing it. The aim of this comprehensive...
Journal Articles
The Clinicopathologic Heterogeneity of Grade 3 Gastroenteropancreatic Neuroendocrine Neoplasms: Morphological Differentiation and Proliferation Identify Different Prognostic Categories
Available to PurchaseMassimo Milione, Patrick Maisonneuve, Francesca Spada, Alessio Pellegrinelli, Paola Spaggiari, Luca Albarello, Eleonora Pisa, Massimo Barberis, Alessandro Vanoli, Roberto Buzzoni, Sara Pusceddu, Laura Concas, Fausto Sessa, Enrico Solcia, Carlo Capella, Nicola Fazio, Stefano La Rosa
Journal:
Neuroendocrinology
Neuroendocrinology (2016) 104 (1): 85–93.
Published Online: 08 November 2016
... Neuroendocrine carcinoma Morphology Proliferation Classification Prognosis Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a heterogeneous group of neoplastic proliferations encompassing a wide spectrum of entities ranging from low proliferative well-differentiated neuroendocrine...
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