... physiological balance and influencing disease trajectories. The pituitary gland, a central player in the endocrine orchestra, exemplifies this complexity with its assortment of hormone-secreting and nonsecreting cells. Summary: The pituitary gland houses several types of cells responsible for hormone production...

...Takashi Nakakura; Kotaro Horiguchi; Takeshi Suzuki Introduction: Axons of magnocellular neurosecretory cells project from the hypothalamus to the posterior lobe (PL) of the pituitary. In the PL, a wide perivascular space exists between the outer basement membrane (BM), where nerve axons terminate...

...Borgohain Anima; Guruswami Gurusubramanian; Vikas Kumar Roy Introduction: Apelin is an endogenous peptide, whose expression has been shown in the hypothalamus, pituitary, and ovary; furthermore, it is also called a neuropeptide, binding to apelin receptor (APJ) for various functions. It has been...

...Mendel Castle-Kirszbaum; Tony Goldschlager; Margaret D Y Shi; Peter J Fuller Water balance is fundamental to all homeostasis. The hypothalamic-pituitary-adrenal axis influences water balance through the effects of corticotropin-releasing hormone and cortisol on arginine vasopressin secretion...

... pituitary gland, its relationship with the hypothalamus, and the birth of neuroendocrinology; through the development of fluorescence microscopy applications, specific labeling strategies, transgenic systems, and intracellular calcium sensors that enabled the study of processes and dynamics at the cellular...

... activity are unknown. In Nile tilapia ( Oreochromis niloticus ), sexual activity and reproduction ability depend on social rank; only dominant males and females reproduce. Here, this characteristic of dominant fish allows us to compare brain and pituitary gene expression in animals that do and do...

...Anna Sundlöv; Katarina Sjögreen-Gleisner; Jan Tennvall; Ludvig Dahl; Johanna Svensson; Anna Åkesson; Peter Bernhardt; Ola Lindgren Introduction: The pituitary gland has a high expression of somatostatin receptors and is therefore a potential organ at risk for radiation-induced toxicity after 177 Lu...

... area representing a crossroads for important adjacent structures. Several lesions, including tumoral, inflammatory vascular, and infectious diseases may affect this area. Although invasive pituitary tumors are the most common neoplasms encountered within the parasellar region, other tumoral (and cystic...

...Ilan Shimon The pituitary fossa is an uncommon site for metastatic tumor spread. Metastatic lesions to the sellar area derived mostly from breast, lung, renal, prostate, and colon cancers, and rarely from other solid and hematologic malignancies. Almost every cancer has been reported as a source...

...Hermann L. Müller Craniopharyngioma (CP) is a rare embryonic malformation of the sellar/parasellar region with a low histological grade. Clinical manifestations are related to hypothalamic/pituitary deficiencies, visual impairment, and increased intracranial pressure. Recent insight...

...Alessandro Maria Berton; Filippo Gatti; Federica Penner; Emanuele Varaldo; Nunzia Prencipe; Francesca Rumbolo; Fabio Settanni; Valentina Gasco; Ezio Ghigo; Francesco Zenga; Silvia Grottoli Introduction: Central diabetes insipidus (CDI) is a frequent complication of pituitary surgery, but its...

... years. Whilst a primary testicular deficit occurs, hypothalamic or pituitary dysregulation may also coexist. This study aimed to compare the hypothalamic response to kisspeptin-54 and the pituitary response to gonadotropin-releasing hormone (GnRH) of older men with those of young men. Methods: Following...

...Yayoi Ikeda; Ayako Tagami; Munekazu Komada; Mifumi Takahashi Background: Kisspeptins are important regulators of the development and function of the hypothalamic-pituitary-gonadal axis. However, the importance of kisspeptin at the pituitary level is unclear. Methods: We examined the expression...

..., Sweden), and (3) ghrelin + CRH combination, each 1 week apart. Samples were taken at 0, 15, 30, 45, 60, 90 and 120 min after administration of ghrelin and/or CRH and stored at -80°C until assayed for ACTH and cortisol by commercially available kits. Magnetic resonance imaging disclosed pituitary...

... member 1 (IGSF1) cause an X-linked syndrome of central hypothyroidism, macroorchidism, delayed pubertal testosterone rise, variable prolactin deficiency and variable partial GH deficiency in childhood. The clinical features and gene expression pattern suggest a pivotal role for IGSF1 in the pituitary...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Somatostatin analogs Pegvisomant Pasireotide Acromegaly Pituitary Growth hormone Insulin-like growth factor-1 Acromegaly is a rare disease characterized...

...Montserrat Garcia-Lavandeira; Esther Diaz-Rodriguez; Dilek Bahar; Angela R. Garcia-Rendueles; Joana S. Rodrigues; Carlos Dieguez; Clara V. Alvarez The recent demonstration using genetic tracing that in the adult pituitary stem cells are normally recruited from the niche in the marginal zone...

... with the descending KP-IR, NKB-IR and SP-IR axon tracts. Human hypothalamic and pituitary tissues from 5 postmenopausal female subjects (53-83 years) were obtained at autopsies [ 7, 26 ] from the Forensic Medicine Department of the University of Debrecen, with the permission of the Regional Committee...

...Hidetaka Suga The hypothalamic-pituitary system is essential to maintain life and control systemic homeostasis, but it is negatively affected by various diseases, leading to serious symptoms. Embryonic stem (ES) cells differentiate into neuroectodermal progenitors when cultured as floating...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Pituitary Adenoma Genome-wide...