... females) after nomifensine (NOM) administration (200 mg orally). NOM is a drug which activates dopaminergic (DA) neurotransmission at the central nervous system level. Blood samples were drawn every hour for 4 h after NOM or placebo administration. On the 4th h thyrotrophin-releasing-hormone (TRH...

... and amineptine were compared to those previously obtained with the use of another IADA, namely, nomifensine. In normoprolactinemic women methylphenidate (20 mg, orally) or amineptine (200 mg, orally) induced a significant decrease in baseline PRL (maximal change from baseline 50% at 90 min), a pattern...

... in the regulation of GH release, DA (5 μg/kg/min infused i.v. for 120 min), L-dopa (500 mg p.o.), L-dopa (100 mg p.o.) plus carbidopa (35 mg p.o.) after pretreatment with carbidopa (50 mg p.o. every 6 h for 1 day), and nomifensine (200 mg p.o.) have been administered to healthy women. Significant elevations...

... and pathological hyperprolactinemia. Failure of cimetidine to affect basal PRL levels was observed in all the subjects not responding to nomifensine, an antidepressant drug which enhances dopaminergic neurotransmission by inhibiting dopamine reuptake in the central dopamine synapses. In the subjects with puerperal...