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Keywords: Neuroendocrine carcinomaClose
Neuroendocrinology (2022) 112 (8): 777–783.
Published Online: 14 October 2021
...Omar Abdel-Rahman; Sheryl L. Koski Objective: This study aimed to assess the survival differences between cisplatin/etoposide versus carboplatin/etoposide chemotherapy regimens in the management of patients with extrapulmonary neuroendocrine carcinomas (NECs). Methods: Administrative cancer care...
Alberto Bongiovanni, Chiara Liverani, Flavia Foca, Valentina Fausti, Giandomenico Di Menna, Laura Mercatali, Alessandro De Vita, Nada Riva, Sebastiano Calpona, Giacomo Miserocchi, Chiara Spadazzi, Claudia Cocchi, Toni Ibrahim
Neuroendocrinology (2021) 111 (9): 895–906.
Published Online: 20 November 2020
... and 83.7% TEM) with a median age of 59 years (range 26–85) years. ECOG performance status was 0–2. Carcinoid syndrome was reported in 12 (12.6%) patients. Twenty (21.1%) patients with grade (G) 3 neuroendocrine carcinoma (NEC) and 9 (9.4%) with G3 neuroendocrine tumors (NETs) were included in the analysis...
Laura Gerard, Jessica Garcia, Arnaud Gauthier, Jonathan Lopez, Alice Durand, Valérie Hervieu, Annie Lemelin, Laurence Chardon, Verena Landel, Benjamin Gibert, Catherine Lombard-Bohas, Lea Payen, Thomas Walter
Neuroendocrinology (2021) 111 (10): 951–964.
Published Online: 23 October 2020
...Laura Gerard; Jessica Garcia; Arnaud Gauthier; Jonathan Lopez; Alice Durand; Valérie Hervieu; Annie Lemelin; Laurence Chardon; Verena Landel; Benjamin Gibert; Catherine Lombard-Bohas; Lea Payen; Thomas Walter Introduction: Gastroenteropancreatic neuroendocrine carcinomas (GEPNEC) are characterized...
Katharina Detjen, Linda Hammerich, Burcin Özdirik, Münevver Demir, Bertram Wiedenmann, Frank Tacke, Henning Jann, Christoph Roderburg
Neuroendocrinology (2021) 111 (3): 217–236.
Published Online: 02 July 2020
... tract and pancreas. GEP-NENs are subdivided according to their differentiation into well-differentiated neuroendocrine tumors (NETs) and poorly differentiated neuroendocrine carcinomas (NECs). Since GEP-NENs represent rare diseases, only limited data from large prospective, randomized clinical trials...
Kentaro Kai, Kaei Nasu, Haruto Nishida, Tsutomu Daa, Ayumi Shikama, Takaya Shiozaki, Masamitsu Kurakazu, Mitsutake Yano, Yuko Imamura, Hideki Tokunaga, Kazuto Tasaki, Yasushi Iida, Yuki Yamada, Hiroyuki Morisawa, Satoshi Nakagawa, Etsuko Fujimoto, Tomohiko Tsuruta, Harunobu Matsumoto, Atsushi Arakawa, Michiko Nonaka, Hirokuni Takano, Takashi Ushiwaka, Taisuke Mori, Kimihiko Ito, Takashi Motohashi, Norihiro Teramoto, Takashi Yamada
Neuroendocrinology (2021) 111 (4): 320–329.
Published Online: 25 February 2020
... type), paraganglioma, non-small/large cell neuroendocrine carcinoma (NEC), mixed NEC, or undifferentiated carcinomas at 20 institutions in Japan were included in this retrospective cross-sectional study. We identified O-NENs through central pathological review using a common slide set, followed...
Neuroendocrinology (2020) 110 (11-12): 994–1000.
Published Online: 28 January 2020
...Wouter T. Zandee; Jan Maarten van der Zwan; Wouter W. de Herder; Marie-Louise F. van Velthuysen Background: Neuroendocrine carcinomas (NECs) are diagnosed through a combination of immunohistochemistry (IHC) and morphology according to WHO guidelines. The presence of these crucial components...
Hiroyuki Okuyama, Masafumi Ikeda, Takuji Okusaka, Masayuki Furukawa, Shinichi Ohkawa, Ayumu Hosokawa, Yasushi Kojima, Hiroki Hara, Gou Murohisa, Kazuhiko Shioji, Akinori Asagi, Nobumasa Mizuno, Motohiro Kojima, Takeharu Yamanaka, Junji Furuse
Neuroendocrinology (2020) 110 (11-12): 988–993.
Published Online: 02 January 2020
... as first-line chemotherapy for unresectable pancreatic neuroendocrine carcinoma (NEC), but second-line chemotherapies have yet to be established. Objectives: We evaluated the safety and efficacy of everolimus in patients with pancreatic NEC refractory or intolerant to platinum-containing chemotherapy...
Julien Hadoux, Pierre Blanchard, Jean-Yves Scoazec, Pascal Burtin, David Planchard, David Malka, Amandine Berdelou, Valérie Boige, Pierre Duvillard, Sophie Leboulleux, Matthieu Faron, Lambros Tselikas, Eric Deutsch, Michel Ducreux, Eric Baudin
Neuroendocrinology (2020) 111 (1-2): 139–145.
Published Online: 22 October 2019
... of developing a malignancy compared with the general population. Second radiation-induced malignancies with different histologies have been described in different organs. Based on individual observations, we hypothesized that neuroendocrine carcinoma (NEC) could arise in irradiated organs. Methods...
Halfdan Sorbye, Eric Baudin, Ivan Borbath, Martyn Caplin, Jie Chen, Jaroslaw B. Cwikla, Andrea Frilling, Ashley Grossman, Gregory Kaltsas, Aldo Scarpa, Staffan Welin, Rocio Garcia-Carbonero, ENETS 2016 Munich Advisory Board Participants
Neuroendocrinology (2019) 108 (1): 54–62.
Published Online: 28 August 2018
...) are classified based on morphology and graded based on their proliferation rate as either well-differentiated low-grade (G1 to G2) neuroendocrine tumors (NET) or poorly differentiated high-grade (G3) neuroendocrine carcinomas (NEC). Recently, a new subgroup of well-differentiated high-grade pancreatic tumors...
Neuroendocrinology (2018) 106 (4): 381–388.
Published Online: 20 December 2017
... the dedifferentiation of the tumor into a neuroendocrine carcinoma G3 (Ki-67 of 80%) including a nonfunctional stage. Bertram.Wiedenmann@charite.de 11 08 2017 7 12 2017 20 12 2017 © 2017 S. Karger AG, Basel 2017 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...
U. Knigge, J. Capdevila, D.K. Bartsch, E. Baudin, J. Falkerby, R. Kianmanesh, B. Kos-Kudla, B. Niederle, E. Nieveen van Dijkum, D. O'Toole, A. Pascher, N. Reed, A. Sundin, M.-P. Vullierme, all other Antibes Consensus Conference participants
Neuroendocrinology (2017) 105 (3): 310–319.
Published Online: 17 February 2017
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Neuroendocrine neoplasm Neuroendocrine tumor Neuroendocrine carcinoma Follow-up TNM staging Chromogranin A Neuron-specific enolase 5-Hydroxyindoleacetic acid NT-pro-brain...
Massimo Milione, Patrick Maisonneuve, Francesca Spada, Alessio Pellegrinelli, Paola Spaggiari, Luca Albarello, Eleonora Pisa, Massimo Barberis, Alessandro Vanoli, Roberto Buzzoni, Sara Pusceddu, Laura Concas, Fausto Sessa, Enrico Solcia, Carlo Capella, Nicola Fazio, Stefano La Rosa
Neuroendocrinology (2016) 104 (1): 85–93.
Published Online: 08 November 2016
...: Gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) are defined as neuroendocrine neoplasms (NENs) with a Ki-67 index >20% according to the 2010 WHO classification. Some reports suggest that this category is heterogeneous. We retrospectively studied a series of 136 patients affected by grade 3 GEP-NECs...
Neuroendocrinology (2016) 104 (2): 105–111.
Published Online: 28 October 2015
... Incidence Neuroendocrine carcinoma Carcinoid Neuroendocrine tumours (NETs) comprise a heterogeneous group of neoplasias originating in a broad diversity of tissues and showing a broad and only partially understood spectrum of clinical behaviour. The term Karzinoid was first used in 1907...
Marco Volante, Valentina Monica, Nadia Birocco, Maria Pia Brizzi, Simone Busso, Lorenzo Daniele, Stefano La Rosa, Luisella Righi, Anna Sapino, Alfredo Berruti, Giorgio V. Scagliotti, Mauro Papotti
Neuroendocrinology (2015) 101 (2): 151–160.
Published Online: 29 January 2015
..., instructions or products referred to in the content or advertisements. Mixed carcinoma Neuroendocrine carcinoma Gene expression Thymidylate synthase Prognosis The concept of human cancers displaying a combination of neuroendocrine and nonneuroendocrine (glandular, squamous or urothelial...