...Roberta Modica; Alessia Liccardi; Roberto Minotta; Elio Benevento; Giuseppe Cannavale; Gianfranco Di Iasi; Annamaria Colao Introduction: Multiple endocrine neoplasia type 1 (MEN-1) is the most common inherited syndrome associated with NET development and gender-specific differences are emerging...

...; Frédéric Triponez; Gerlof D. Valk; Dermot O’Toole; David Scott-Coombes; Rajesh V. Thakker; Geoffrey B. Thompson; Giorgio Treglia; Bertram Wiedenmann The better understanding of the biological behavior of multiple endocrine neoplasia type 1 (MEN1) organ manifestations and the increase in clinical experience...

.... Vriens Background: Pancreatic neuroendocrine tumors (pNETs) have a high prevalence in patients with multiple endocrine neoplasia type 1 (MEN1) and are the leading cause of death. Tumor size is still regarded as the main prognostic factor and therefore used for surgical decision-making. We assessed...

... of pancreatic neuroendocrine tumors (PNETs), allowing repeat monitoring examinations in multiple endocrine neoplasia type 1 (MEN-1) patients. Objectives: We aimed to compare the diagnostic accuracy of conventional MRI sequences to identify which sequence better depicts the presence of PNETs in MEN-1 patients...

...Rachel S. van Leeuwaarde; Carolina R.C. Pieterman; Anne M. May; Olaf M. Dekkers; Anouk N. van der Horst-Schrivers; Ad R. Hermus; Wouter W. de Herder; Madeleine L. Drent; Peter H. Bisschop; Bas Havekes; Menno R. Vriens; Gerlof D. Valk Introduction: Multiple endocrine neoplasia type 1 (MEN1...

...) are the most common cause of death in adult patients with multiple endocrine neoplasia type 1 (MEN1). So far, only few chemopreventive strategies (e.g., with somatostatin analogues) have been evaluated for MEN1 associated pNENs. In this experimental study on 75 Men1 (+/T) knockout mice, the effect of aspirin...

... for nonfunctioning pancreatic neuroendocrine neoplasms (NF-PNEN) ≤2 cm in multiple endocrine neoplasia type 1 (MEN1)-affected patients compared with surgical treatment. Methods: The databases of 4 tertiary referral institutions (San Raffaele Scientific Institute, Milan; Philipps-Universität Marburg, Marburg...

... disease. The Ki-67 index was 1-5% (median 2%). Plasma somatostatin was elevated in the patients with 2B disease. Of the 14 patients with pancreatic SOM or an unknown primary tumour, the male/female ratio was 2/12. One male had multiple endocrine neoplasia type 1. Five had stage 1A/2B and 9 had stage 4...

..., instructions or products referred to in the content or advertisements. Bronchopulmonary neuroendocrine neoplasms Multiple endocrine neoplasia type 1 Carcinoid Neuroendocrine precursor lesion Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant inherited disorder caused...

...Detlef K. Bartsch; Max Albers; Richard Knoop; Peter H. Kann; Volker Fendrich; Jens Waldmann Aim: To assess the characteristics and long-term outcome after surgery in patients with multiple endocrine neoplasia type 1 (MEN1)-associated insulinoma. Methods: Retrospective analysis of prospectively...

...Maria Vittoria Davì; Letizia Boninsegna; Luca Dalle Carbonare; Marco Toaiari; Paola Capelli; Aldo Scarpa; Giuseppe Francia; Massimo Falconi Aim: To assess presentation and outcome of pancreaticoduodenal endocrine tumors (PDETs) in a single center series of multiple endocrine neoplasia type 1 (MEN1...

... among others. Cushing’s disease can be an inherited condition also. Multiple endocrine neoplasia type 1 (MEN1) and familial isolated pituitary adenomas (FIPA) together account for 5% of pituitary adenomas. Cushing’s disease occurs infrequently in an inherited setting in both of these conditions. To date...

...Aristides Lytras; George Tolis Hereditary cases of growth hormone (GH)-secreting tumors have been classified into three clinical entities: the multiple endocrine neoplasia type 1 (MEN1) syndrome, the Carney complex (CNC) and the isolated familial somatotropinomas (IFS). The genomic defects...

... of a multiple endocrine neoplasia type 1 syndrome or rarely the von Hippel-Lindau syndrome. EPTs have been of great interest to endocrine surgeons and we have, during recent years, witnessed continuing advances in diagnosis, imaging and treatment of the different tumour entities. It has become obvious...