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Keywords: Melatonin receptors
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Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2009) 90 (3): 251–259.
Published Online: 30 July 2009
...–7 cells), the present study investigated the mechanism by which the expression of melatonin receptors is regulated in GnRH neurons. Like endogenous GnRH neurons, GT1–7 cells express both GnRH and GnRH receptor mRNAs, indicating that the cells have a self-stimulatory system. A 2-iodomelatonin binding...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (1993) 57 (1): 120–126.
Published Online: 08 April 2008
... that there is no tissue-specific regulation of melatonin receptors between PT and SCN and (2) suggest that the daily variations in plasma melatonin concentrations could be implicated in the regulation of the density of melatonin binding sites both in the rat PT and SCN, probably by a mechanism of desensitization...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (1989) 50 (3): 359–362.
Published Online: 02 April 2008
... are consistent with a melatonin receptor existing in an equilibrium between high- and low-affinity states, with GTP and related analogues able to cause a shift in the equilibrium in favour of the lower-affinity form. The sensitivity of 2-[ 125 I]-melatonin binding to guanine nucleotides implies the presence...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2005) 81 (2): 87–95.
Published Online: 06 July 2005
... in estradiol-treated cells but not in control CHO-MT 1 cells, suggesting that estradiol promotes constitutive activity of MT 1 melatonin receptors. We suggest that 17β-estradiol differentially affects MT 1 and MT 2 melatonin receptor functions, attenuates melatonin responses through activation of MT 1...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2004) 79 (2): 63–72.
Published Online: 12 March 2004
... from any ideas, methods, instructions or products referred to in the content or advertisements. Gonadotropin-releasing hormone GT1–7 Neurons Melatonin Melatonin receptors Transcription factors GnRH is the prevailing hormone of the HPG axis and is secreted in a pulsatile manner from...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2001) 74 (4): 262–269.
Published Online: 05 October 2001
...Hana Zemkova; Jiri Vanecek In neonatal rat gonadotropes, melatonin inhibits gonadotropin-releasing-hormone (GnRH)-stimulated increase in intracellular Ca 2+ concentration ([Ca 2+ ] i ); in cells transfected with the Mel1a melatonin receptor, however, melatonin has been shown to potentiate agonist...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2001) 74 (3): 178–184.
Published Online: 30 August 2001
... unknown, however, which melatonin receptor subtype mediates immune enhancement by melatonin. The present study examined the contribution of specific melatonin receptor subtypes, mt1 (Mel 1a) and MT2 (Mel 1b), in mediating melatonin-induced enhancement of cell-mediated and humoral immune function in mice...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2001) 74 (1): 55–68.
Published Online: 06 July 2001
...Carole Schuster; François Gauer; André Malan; Joaquim Recio; Paul Pévet; Mireille Masson-Pévet Mechanisms underlying the daily and photoperiodic variations in mt 1 melatonin receptors were investigated in the pars tuberalis (PT) and suprachiasmatic nuclei (SCN) of Siberian and Syrian hamsters...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2000) 72 (1): 57–66.
Published Online: 23 July 2000
... (Mel 1a ) and the P2.6 (Mel 1b ) melatonin receptor subtypes. The two corresponding transcripts were expressed in the pituitary as revealed by RT-PCR assay and Southern blot hybridization. In culture, melatonin inhibited in a time- and dose-dependent manner cyclic AMP levels in pituitaries cultured...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2000) 71 (3): 163–169.
Published Online: 20 March 2000
...Hilda Y. Guerrero; François Gauer; Carole Schuster; Paul Pévet; Mireille Masson-Pévet The pars tuberalis (PT) of the pituitary is a major neuroendocrine target site for melatonin as it contains a large number of high-affinity melatonin receptors. We have previously shown that melatonin...