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Keywords: MYC
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Journal Articles
MYC Upregulation Confers Resistance to Everolimus and Establishes Vulnerability to Cyclin-Dependent Kinase Inhibitors in Pancreatic Neuroendocrine Neoplasm Cells
Available to PurchaseFrancesca Terracciano, Alessia Capone, Andrea Montori, Maria Rinzivillo, Stefano Partelli, Francesco Panzuto, Emanuela Pilozzi, Paolo Giorgio Arcidiacono, Claudio Sette, Gabriele Capurso
Journal:
Neuroendocrinology
Neuroendocrinology (2021) 111 (8): 739–751.
Published Online: 02 July 2020
... by quantitative PCR analysis. RNA extracted from patients’ biopsies was used to validate MYC upregulation. Drug screening and functional assays were performed using ER-BON-1 cells. Cell cycle progression was evaluated by FACS analysis. Results: Our results show that MYC overexpression is a key event...
