...Akira Miyake; Shirou Ohtsuka; Takamichi Nishizaki; Keiichi Tasaka; Toshihiro Aono; Osamu Tanizawa; Atsushi Yamatodani; Takehiko Watanabe; Hiroshi Wada For determination of the roles of histamine and its receptors, H 1 and H 2 , in the control of basal and estrogen-induced LH-RH secretion...

...Pushpa S. Kalra We have previously reported that luteinizing hormone releasing hormone (LH-RH) levels in the medial basal hypothalamus (MBH) of adult male rats castrated for 2 weeks can be raised by testosterone (T) or estradiol (E2) treatment for 3–4 days. The present study was undertaken...

...Jean Y. Jew; Csaba Léránth; Akira Arimura; Miklos Palkovits Glass microknife lesions and immunocytochemistry were used to evaluate luteinizing hormone-releasing hormone (LH-RH)- and somatostatin (SS)-immunoreactive pathways from the preoptic region to the rat median eminence.Cuts were so placed...

...Michel Heaulme; Fernand Dray Noradrenaline (NA) and prostaglandin (PG) E 2 produced a dose-related stimulation of luteinizing hormone releasing hormone (LH-RH) release from incubated median eminence of adult male rats, with ED50 values of 6.10 –7 and 8.10 –8 M, respectively. The effects of some...

...Albert Chan; Carol A. Dudley; Robert L. Moss The spontaneous firing rate of midbrain central gray (MCG) neurons and the effect of iontophoretically applied prolactin and luteinizing hormone releasing hormone (LH-RH) on the electrical activity of these neurons was studied in untreated and estrogen...

... antiserum to LHRH or control serum, or (3) infused with a luteinizing hormone releasing hormone (LH-RH) analog, [D-pGlu 1 , D-Phe 2 , D-Trp 36 ]-LH-RH. Castrates exhibited a pulsatile pattern of circulating LH levels; the mean (±SE) peak level of LH pulses was 640 ± 15 ng/ml, with a mean (±SE) pulse period...

...-RH and dopamine in the male rat. Male rats of the same age not inoculated with the tumor served as controls. Hypophysial stalk blood was collected from urethane-anesthetized rats 4-5 weeks after tumor inoculation to measure their LH-RH and dopamine content. A peripheral blood sample was withdrawn...

...S.E. Recabarren; J.E. Wheaton Ovariectomized (Ovx) rats were treated (s.c.) with estradiol benzoate (E 2 B) for 7 days, and then 10, 25 or 100 ng LH-RH were microinjected into the 3rd ventricle. Intraventricular LH-RH elevated plasma LH at 10 and 30 min in a dose-response manner. In experiment 2...

... values. To these animals implanted with T capsules, androstenedione (Δ 4 ), 5 α -androstane-17 β -ol-3-one (DHT), 5 α -androstane-3 α -17 β -diol (3 α -OL) or T were administered by subcutaneous injections (40 μg/100 g body weight). 12 h later, the animals received an intravenous injection of 50 ng LH-RH...

... the lesion. Serum LH, FSH and prolactin and hypothalamic LH-RH content of 3 different parts of the hypothalamus were determined with radioimmunoassay. OVLT lesion caused a significant increase in the LH-RH content of the mid-basal hypothalamus and in serum prolactin levels and a decrease in LH and FSH serum...

...A. Castro-Vazquez; S.R. Ojeda Pituitary responsiveness was evaluated after a single or two consecutive i.v. injections of LH-RH at the time of puberty in the female rat. A single injection of LH-RH (20 or 100 ng/100 g b.w.) significantly elevated plasma LH levels in prepubertal rats (anestrous...

...S.H. Shin; C. Howitt LH-RH in rat hypothalamic extract (HE) emerges in 2 peaks after gel filtration on Sephadex G-25 with pyridine acetate buffer (PAB), pH 5.8,1 peak in the unretarded protein fraction and the other near the salt region. A synthetic LH-RH marker was found only in the peak near...

...G.P. Trentini; C.F. de Gaetani; F. Campostrini The injection of LH-RH induced ovulation in constant estrous rats (CEA), made anovulatory either by frontal hypothalamic deafferentation (FHD), or by exposure to continuous light (CL), or by neonatal androgenization (NA) with 0.500 mg testosterone...

...R.W. Hall; E. Steinberger Following the procedure of Jeffcoate et al. [1974] we have successfully obtained a specific antiserum to LH-RH in rabbits, and are utilizing our antibody to study the synthesis of LH-RH by rat hypothalamic tissues in vitro. Our antibody, used at a dilution of 1:20,000...

...S.H. Shin; C.J. Howitt Hypothalamic LH-RH content in male rats is lowered after castration. The s.c. implantation of testosterone or testosterone propionate-packed Silastic tubing (from 0.5 to 6 cm in length) in a range which encompassed the normal circulating plasma testosterone concentration...

...R.J. Krieg, jr.; O.P. Tandon; D.I. Whitmoyer; C.H. Sawyer Effects of intiaventricular infusions of LH-RH and norepinephrine (NE) on the electrical activity of the arcuate nucleus were investigated in normally cycling proestrous rats. Under urethane anesthesia, recordings were made of amplitude...

...R.W. Hall; E. Steinberger Normal, castrate and estradiol benzoate (EB; 1 µ g/100 g b.w. × 6d, s.c.)-treated castrate male rats were utilized to study the short term effects of these treatments upon the incorporation of 3 H-glycine into LH-RH in vitro . The rise in serum LH and FSH observed...

... LH-RH Puberty Ovulation PMS Neuroendocrinology 24: 270-288 (1977) Evidence for an Inhibitory Dopaminergic and Stimulatory Noradrenergic Hypothalamic Influence of PMS-Induced Ovulation in the Immature Rat. I. Catecholamine Turnover Changes in Relation to the Critical Period A . L ofstrOm, L . F...

...-HT) neurotransmission did not affect ovulation. LH-RH removed the ovulatory blockade induced by ET 495 in the same dose-range as it removed pentobarbital-induced blockade of ovulation. Furthermore, ergocornine did not block ovulation after the critical period and was less effective when given prior...

...R.L. Eskay; J. Warberg; J.C. Porter Prostaglandin E 2 (PGE 2 ), PGF 2 α , or PGF 2 β was infused into a lateral ventricle of the brain of adult male rats, after pretreatment with normal rabbit serum (NRS) or anti-LH-RH serum, and the concentration of LH in arterial plasma was determined. I.v...