...) and β-endorphin in melanotropes of the intermediate lobe (IL) of the pituitary gland. While ACTH secretion is predominantly under the stimulatory influence of the hypothalamic factors, hormone secretion of the IL is tonically inhibited by neuroendocrine dopamine (NEDA) neurons. Lobe-specific POMC...

... of a-Melanocyte-Stimulating Hormone Release in Frog Pituitary Is Mediated by both P- and a Nonconventional a2-Subtype of Adrenoreceptors Key Words Intermediate lobe a-Melanocyte-stimulating hormone Catecholamines Catecholamine receptors Amphibia Abstract Previous studies have shown that melanotrope cells...

...Andreas Kjær; Ulrich Knigge; Flemming W. Bach; Jørgen Warberg Stress stimulates secretion of the pro-opiomelanocortin (POMC)-derived peptides adrenocorticotropic hormone (ACTH), β-endorphin (β-END) and α-melanocyte-stimulating hormone (α-MSH) from the anterior lobe (AL) and intermediate lobe (IL...

... . The glutamate-induced Ca 2+ influx was about half of that elicited by a 50 m M K + -induced membrane depolarization and activation of voltage-sensitive Ca 2+ channels. These results demonstrate the presence of glutamate receptors on rat melanotropes and suggest that glutamate receptors in the intermediate lobe...

...John L. Goudreau; William M. Falls; Keith J. Lookingland; Kenneth E. Moore The purpose of the present study was to determine the relative distribution of axon terminals of A 14 periventricular-hypophysial dopaminergic (PHDA) neurons in the neural and intermediate lobes of the rat pituitary gland...

... intermediate lobe (IL) cells using the whole-cell configuration of the patch-clamp technique. In a standard Na + -based extracellular solution, glutamate failed to induce a detectable membrane current at a holding potential (HP) of –60 mV (n = 40). However, when cyclothiazide (50 µ M ), a benzothiazide...

... Corticotropes Intermediate lobe Amphibia -endocrinology Comparative Neuroendocrinology Neuroendocrinology 1997;65:413-422 Received: November 15. 1996 Accepted after revision: February 11. 1997 Ruud Ubink Bruce G. Jenks Eric W. Roubos Department of Cellular Animal Physiology, Nijmegen Institute...

...John L. Goudreau; Steven E. Lindley; Keith J. Lookingland; Kenneth E. Moore The purpose of the present study was to provide neurochemical and endocrinological evidence that dopamine (DA) neurons terminating in the intermediate lobe of the rat pituitary originate in the periventricular nucleus...

...James A. Carr; Linda C. Saland; Ann Samora; Salvador Benavidez; Kurt Krobert We used an in vivo pharmacological approach to investigate the potential influence of serotonin (5-HT) on peptide release from the intermediate lobe (IL) of the rat pituitary. Plasma levels of α-melanocyte-stimulating...

... or 30 min of supine restraint increased plasma αMSH concentrations and decreased DOPAC concentrations in the intermediate lobe of female and male rats. In the absence of ether, tube restraint (confinement in a cylindrical acrylic tube) increased αMSH secretion and decreased intermediate lobe DOPAC...

... upregulates the POMC system in IL, but downregulates it in AL, despite similarities of the responses of both lobes to acute haloperidol challenge. 6 09 1988 14 08 1989 3 4 2008 Pro-opiomelanocortin Haloperidol Pituitary Anterior lobe Intermediate lobe Dopamine β-Endorphin...

... of 3,4-dihydroxyphenylalanine (DOPA) following the administration of a decarboxylase inhibitor in brain regions that contain terminals of nigrostriatal (striatum), mesolimbic (nucleus accumbens), tuberoinfundibular (median eminence) and tuberohypophysial (neural and intermediate lobe of the pituitary...

...A. Ian Smith; Catherine A. Wallace; Iain J. Clarke; John W. Funder Hypothalamo-pituitary disconnection (HPD) in the sheep results in a two-fold increase in pituitary intermediate lobe (IL) immunoreactive (ir)-α-N-acetylated endorphin (NacEP) and ir-α-melanocyte-stimulating hormone (αMSH) content...

...Sarah Schimchowitsch; J. Maria Palacios; Marie Elisabeth Stoeckel; Gabrielle Schmitt; Aimé Porte No immunoreactive axons were detected with an antiserum against tyrosine hydroxylase in the rabbit intermediate lobe (IL), which thus appears to be devoid of dopaminergic (DA) innervation. Dopamine...

...J.-L. Bény; A.J. Baertschi Electrical stimulation of rat posterior lobes in vitro inhibited bioactive corticotropin (ACTH) release from the intermediate lobe and promoted the release of corticotropin-releasing factor(s) (CRF). Both effects were calcium dependent. Released posterior lobe CRF...

...T.E. Cote; R.L. Eskay; E.A. Frey; C.W. Grewe; M. Munemura; J.C. Stoof; K. Tsuruta; J.W. Kebabian The intermediate lobe (IL) of the rat pituitary gland responds to catecholamines. Catecholamines interacting with the β-adrenoceptor stimulate adenylate cyclase activity, enhance cyclic AMP formation...

... that its blocking effect is exerted before either the intermediate lobe or the neurons secreting MSH-release-inhibiting factor. Treatment of the animals with p -chlorophenylalanine or the injection of methysergide (10 µ g) into the 3rd ventricle prevented the drop in pituitary MSH concentration which can...

... to the dopaminergic arcuate-intermediate lobe system. Control of MSH Intermediate lobe Dopamine © 1975 S. Karger AG, Basel 1975 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...

... MSH activity was the same as in controls. Male rats also demonstrated elevated plasma MSH levels (p < 0.05) when measured 23 days postoperatively. Histological evaluation of pituitaries from these animals revealed no changes in the intermediate lobe. These data suggest that MSH release from...

... Catecholamines Hypothalamus Intermediate lobe Reserpine Dibenamine Ncuroendocrinology 10: 235-245 (1972) Role of Catecholamines in the Control of Melanocyte-Stimulating Hormone Secretion in Rats S. Taleisnik, Maria E. Tomatis and Maria E. Celis Instituto de Investigación Medica, Mercedes y Martín...