... can modify PV expression in the hippocampus. Methods: We employed biochemical, immunohistochemistry, and densitometry techniques – as well as a behavioural assay – in a hyperprolactinemia model using subcutaneous osmotic pumps in female mice. Results: PRL treatment via osmotic pump induced an increase...

...Lucio Vilar; Clarice Freitas Vilar; Ruy Lyra; Maria da Conceição Freitas An appropriate diagnostic evaluation is essential for the most appropriate treatment to be performed. Currently, macroprolactinemia is the third most frequent cause of nonphysiological hyperprolactinemia after drugs...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hyperprolactinemia Pituitary tumor Dopamine agonists Bromocriptine Cabergoline Lisuride Pergolide Quinagolide Indications for therapy in patients...

...Sandra Pekić; Milica Medic Stojanoska; Vera Popovic Hyperprolactinemia is not a common finding in postmenopausal women. Prolactinomas detected after menopause are usually macroadenomas. Due to atypical clinical features they may remain unrecognized for a long period of time. Interestingly...

...Renata S. Auriemma; Mariano Galdiero; Pasquale Vitale; Luciana Granieri; Fabio Lo Calzo; Ciro Salzano; Lucia Ferreri; Claudia Pivonello; Federica Cariati; Giorgio Coppola; Cristina de Angelis; Annamaria Colao; Rosario Pivonello Introduction: Hyperprolactinemia and hypogonadism are reportedly...

...Renata S. Auriemma; Luciana Granieri; Mariano Galdiero; Chiara Simeoli; Ylenia Perone; Pasquale Vitale; Claudia Pivonello; Mariarosaria Negri; Teresa Mannarino; Carla Giordano; Maurizio Gasperi; Annamaria Colao; Rosario Pivonello Introduction: Hyperprolactinemia has been implicated...

..., and parathyroid hormone were assessed. Indices of insulin sensitivity and resistance were determined following an oral glucose tolerance test (OGTT). Bone mineral density (BMD) was measured by dual X-ray absorptiometry at the lumbar spine (LS) and femoral neck (FN). Results: Mild to moderate hyperprolactinemia...

... is involved in the suppressed secretion of LH during hyperprolactinemia. The aim of this study was to explore this possibility in hyperprolactinemic male rats. Hyperprolactinemia, induced by insertion of 3 pituitary glands under the kidney capsule, decreased plasma LH levels by 68% and caused a 2-fold...

... Rats Keywords Cyclosporine Pulsatility Prolactin Luteinizing hormone Hyperprolactinemia Abstract This study was designed to examine whether cyclosporine (CyA) acts on the endocrine system by modifying the pulsatile secretion pattern of prolactin and LH. Both pituitary-grafted and sham-operated rats...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hyperprolactinemia Pulsatile LH release Pulse frequency Pulse amplitude Exogenous prolactin Hypothalamic Gonadal Axis Neuroendocrinology 1993;58:448 453 Sung-Keun Park...

... are compromised by tumor-induced HP, effects which could be mediated directly at the pituitary and/or by decreased LHRH release, and (4), that PRL can act directly on the brain and/or pituitary to inhibit the E2-induced LH surge. Neuroendocrinology 1991 ;54:227 235 Effects of Tumor-Induced Hyperprolactinemia...

...Sung-Keun Park; Michael Selmanoff We examined the inhibitory effects of acute hyperprolactinemia on the postcastration rise in mean luteinizing hormone (LH) levels in adult male rats. The animals were administered purified ovine prolactin (oPRL) subcutaneously in a polyvinyl-pyrrolidone depot every...

...Susan R. Fox; Michael T. Hoefer; Andrzej Bartke; M. Susan Smith To assess whether gonadotropin-releasing hormone (GnRH) release from the hypothalamus might be altered by hyperprolactinemia in the male rat, we measured in chronically hyperprolactinemic rats the pituitary GnRH receptor content...

...Nancy G. Weiland; Phyllis M. Wise Hyperprolactinemia suppresses endogenous prolactin (PRL) secretion and inhibits LH release in ovariectomized rats. Opiate peptides appear to mediate the suppressive effects of hyperprolactinemia on both endogenous PRL and LH secretion. A mechanism by which...

... Hyperprolactinemia Abstract. Recent evidence suggests that increased plasma prolactin (PRL) levels could be modifying the synthesis and release of catecholamines (CA) from the adrenal medulla. In order to study this possibility, female rats bearing an anterior pituitary gland, from a litter-mate donor, under...

...Katia Felman; Marcel Tappaz The effect of chronic hyperprolactinemia was studied on (a) GABA concentration in the pituitary anterior lobe; (b) GABA biosynthesis enzyme, glutamate decarboxylase (GAD) activity in the hypothalamic median eminence, and (c) GABA degradation enzyme GABA-transaminase...

... and reduced norepinephrine metabolism in preoptic area and olfactory bulbs. Hyperprolactinemia induced by grafting three anterior pituitary glands beneath the kidney capsule blocked female-induced changes in norepinephrine metabolism and attenuated the increase in luteinizing hormone release. These results...

... it appears that a relatively brief exposure to DES in early adulthood causes marked and persistent changes in tuberoinfundibular DA function that are responsible for continued hyperprolactinemia. Associated reductions in LH secretion also appear to be due to hypothalamic as opposed to pituitary factors. ©...

...Paul C. Doherty; Michael J. Baum; Roberta B. Todd Studies were conducted to determine if the inhibitory effects of chronic hyperprolactinemia on sexual behavior in male rats occur through reduced sexual arousal as opposed to reduced erectile function. Pituitary-grafted (hyperprolactinemic) and sham...

...Ilene R. Cohen-Becker; Michael Selmanoff; Phyllis M. Wise Studies were undertaken to (1) examine the effects of hyperprolactinemia on the frequency and amplitude of pulses of LH, and (2) determine if changes in pituitary sensitivity to LHRH were involved in the prolactin-induced suppression of LH...