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Keywords: Homeodomain
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Journal Articles

Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2 Causes Subfertility in Mice via Distinct Mechanisms

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Subject Area:
Endocrinology , Neurology and Neuroscience
Hanne M. Hoffmann, Erica C. Pandolfi, Rachel Larder, Pamela L. Mellon
Journal: Neuroendocrinology
Neuroendocrinology (2019) 109 (3): 200–207.
https://doi.org/10.1159/000494086
Published Online: 27 September 2018
... of normal activity and function. Reproduction is a complex process relying on migration of GnRH neurons from the olfactory placode to the hypothalamus during development. We have studied 3 different homeodomain genes Otx2, Vax1, and Six3 and found that the deletion of one allele for any of these genes...
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Journal Articles

Transcriptional Properties of Ptx1 and Ptx2 Isoforms

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Subject Area:
Endocrinology , Neurology and Neuroscience
Jacques J. Tremblay, Cynthia G. Goodyer, Jacques Drouin
Journal: Neuroendocrinology
Neuroendocrinology (2000) 71 (5): 277–286.
https://doi.org/10.1159/000054547
Published Online: 22 May 2000
... to in the content or advertisements. Pituitary Transcription factors Hormone-coding genes Homeodomain Pitx family Cell-specific transcription Molecular neuroendocrinology Ptx1 (Pitx1) was first identified as a transcription factor involved in proopiomelanocortin (POMC) gene expression [ 1...
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