... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Memory Metabolism Cortisol 11β-hydroxysteroid dehydrogenase Hippocampus Diabetes is defined...

... increased the secretion of growth hormone, resulting in changes in body size and endocrine functions, thus causing acromegaly. The acromegaly model showed deficiencies in working memory and spatial memory. Hyperphosphorylation of tau protein was observed in the hippocampus of the acromegaly model, but no Aβ...

...) slope and population spike (PS) amplitude were recorded from the granule cell layer of the dentate gyrus. The mRNA levels of genes related to neurodegeneration (Gsk-3β, Cdk5, Akt1, Mapt, p35, Capn1, Bace1, and Psen2) were measured using the RT-PCR method for the stimulated hippocampus. Results: Similar...

... including hyperactivity in the hippocampus during the early stage of diabetes. This study aimed to determine the changes in neuronal activity at a single-cell level in hippocampal CA1 pyramidal neurons in the early stage of streptozotocin-induced type 1 diabetes in mice. Methods: Whole-cell patch-clamp...

...Alexandra M. Vaiana; Amber M. Asher; Karla Tapia; David A. Morilak Introduction: Androgen deprivation therapy (ADT) is a mainstay treatment for prostate cancer, but many patients experience cognitive impairment in domains mediated by the medial prefrontal cortex (mPFC) and hippocampus. Prostate...

... (CORT) levels. All participants underwent personality assessment using Minnesota Multiphasic Personality Inventory-2 (MMPI-2). Results: BD patients with SA exhibited increased dFC variability between the right caudal hippocampus and the left superior temporal gyrus (STG) when compared with non-SA BD...

...Tenna Bering; Aurea Susana Blancas-Velazquez; Martin Fredensborg Rath Introduction: In the hippocampus, clock gene expression is important for memory and mood; however, the signaling mechanism controlling clock gene expression in the hippocampus is unknown. Recent findings suggest that circadian...

..., such as the hippocampus, an essential mediator of learning and memory processes. Indeed, during development, the hippocampus is subjected to the organizational effects of estrogens and androgens, which influence hippocampal cell proliferation, differentiation, dendritic growth, and synaptogenesis in the hippocampal...

...Ahmed S. Ahmed; Marwa M. Mona; Rasha A. Elsisy; Ehab M. Hantash Introduction: Diet rich in purines may increase the serum level of uric acid causing hyperuricemia, contributing to learning and memory to impairments. Ascorbic acid has a potent antioxidant potential. The hippocampus is a pivotal...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Hippocampus Endocrine-disrupting chemicals Newborn granule cells...

...Karolína Liška; Martin Sládek; Pavel Houdek; Norzin Shrestha; Vendula Lužná; Martin R. Ralph; Alena Sumová Aims: Circadian clocks in the hippocampus (HPC) align memory processing with appropriate time of day. Our study was aimed at ascertaining the specificity of glycogen synthase kinase 3-beta...

... in the neocortex and hippocampus by liquid chromatography/mass spectrometry in epileptic rats. Methods: Kainic acid-treated rats were continuously monitored up to 9 weeks to determine seizure frequency by video electrocorticography ( n = 23) and compared to age-matched controls monitored in the same manner ( n...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Glucocorticoids Memory Stress Hippocampus...

... Estrogen receptor-α Sex differences Hippocampus Hypoxia-ischemia Encephalopathy Tyrosine kinase receptor National Institutes of Health (NIH) 10.13039/100000002 At the Cutting Edge Neuroendocrinology 2019;109:249 256 DOI: 10.1159/000499661 Received: November 25, 2018 Accepted after...

... showing many dark and round somata and thick processes. Estradiol Hippocampus Glucose deprivation Neuronal death Neuroprotection Estrogen receptors Trypsin, DNase, gentamicin, L -glutamine, poly-L-lysine, cytosine arabinoside, β-estradiol-water soluble, and 3-(4,5-dimethylthiazol-2-yl...

..., such as the hippocampus, cortex and cerebellum. To date, the majority of preclinical work has investigated the developmental effects of SSRIs in the offspring of healthy mothers; however, more research is needed on the effects of these medications in the face of maternal adversity. This minireview will highlight emerging...

... in humans and animal models. Leptin receptor-deficient mice ( db/db) show reduced expression of brain-derived neurotropic factor (BDNF) in the hippocampus and increases in circulating corticosterone levels, but the extent to which elevated corticosterone levels mediate deficits in BDNF expression has...

... of chronic stress on the regulation of glucocorticoid receptivity, mineralocorticoid receptor (MR) and glucocorticoid receptor mRNA expression was assessed in the hippocampus, frontoparietal cortex and PVN. Chronic stress significantly down-regulated MR mRNA expression in subfields CA1, CA3 and the dentate...

... and inferior olive. The CR16 RNA has low prevalence in the hippocampus and cortex (<10 pg/µg total RNA) and is elevated 3-fold in both structures in a dose-dependent manner by CORT in ADX rats. Treatment of ADX rats with aldosterone (ALDO), CORT, or RU28362 increased CR16 RNA to similar levels...

... Hybridization, in situ Thyrotropin-releasing hormone Thyroid hormone Limbic system Amygdala Hippocampus 17 05 1995 14 09 1995 9 4 2008 © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...