... the growth hormone secretagogue receptor (GHSR). GHSR is expressed in hypothalamic arcuate (ARC) Kisspeptin/Neurokinin B (Tac2) /Dynorphin (KNDy) neurons. Ghrelin is known to inhibit the M-current produced by KCNQ channels in other ARC neurons. In addition, we have shown 17β-estradiol (E2) increases Ghsr...

... that interaction of the melanocortin 3 receptor (MC3R) and the growth hormone secretagogue receptor (GHSR)-1a results in a modulation of function in both receptors. Although the physiological role of GPCR-GPCR interaction in the hypothalamus is yet to be elucidated, this concept promises new avenues...

...-opiomelanocortin Arcuate nucleus Diet-induced obesity Calorie restriction Growth hormone secretagogue receptor Glucose homeostasis Food intake Intriguingly, we observed increased ROS production in POMC neurons compared to NPY neurons under basal conditions, suggesting POMC neurons might be prone to free...

...Masateru Katayama; Haruo Nogami; Junichirou Nishiyama; Takeshi Kawase; Koki Kawamura Distribution and development of growth hormone secretagogue receptor (GHS-R) mRNA expression in rat brain and pituitary gland were examined using ribonuclease protection assay. In adult male rats, GHS-R mRNA levels...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Growth hormone secretagogue receptor Co-localization Dual in situ hybridization Neuropeptide Y Pro-opiomelanocortin Somatostatin Arcuate nucleus Rat...

... not significantly alter either pituitary or hypothalamic GHS-R mRNA levels, indicating that GH acts independent of circulating IGF-I to regulate pituitary GHS-R expression in the SDR model. Growth hormone Dwarf Growth hormone secretagogue receptor Growth hormone-releasing hormone Somatostatin Fig. 3...