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Keywords: Growth hormone
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Neuroendocrinology (2022) 112 (3): 276–286.
Published Online: 26 April 2021
... of sellar tumours [3]. Lactotroph and some growth hormone (GH)-secreting tumours can respond to medical therapy [4]. Surgery is the treatment of choice for clinically non-functioning tumours [5]. The role of MRI in predicting the endocrine status of adenohypophyseal tumours is not clear, with studies...
Journal Articles
Neuroendocrinology (2022) 112 (1): 1–14.
Published Online: 15 January 2021
..., such as growth hormone (GH) and gonadal hormones, and the increase in the synthesis of hormones with catabolic properties such as cortisol, as shown in Figure 1 . These adaptations go in parallel with an increase in pituitary-related diseases due to the higher life expectancy. In the literature, the age-related...
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Neuroendocrinology (2019) 108 (3): 244–255.
Published Online: 25 January 2019
...Mirella Hage; Peter Kamenický; Philippe Chanson The exact physiological basis of acute growth hormone (GH) suppression by oral glucose is not fully understood. Glucose-mediated increase in hypothalamic somatostatin seems to be the most plausible explanation. Attempts to better understand its...
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Neuroendocrinology (2015) 102 (4): 288–299.
Published Online: 29 May 2015
.... Similar to Nrg1α, Nrg1β increased the prolactin (PRL) expression in rat pituitary RC-4B/C cells, which can be inhibited by an Akt inhibitor. In addition, Nrg1β had no apparent effect on growth hormone expression at the mRNA or protein levels. Collectively, we conclude that hypothalamic Nrg1 may...
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Neuroendocrinology (2016) 103 (1): 50–58.
Published Online: 12 February 2015
...Philippe Chanson Treatment of acromegaly aims to correct (or prevent) tumor compression of surrounding tissues by excising the disease-causing lesion and reduce growth hormone (GH) and IGF-1 levels to normal values. When surgery (the usual first-line treatment) fails to correct GH/IGF-1...
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Neuroendocrinology (2016) 103 (1): 66–74.
Published Online: 30 January 2015
...John McCabe; John Ayuk; Mark Sherlock Acromegaly is a rare condition characterized by excessive secretion of growth hormone (GH), which is almost always due to a pituitary adenoma. Acromegaly is associated with significant morbidity such as hypertension, type 2 diabetes, cardiomyopathy, obstructive...
Journal Articles
Neuroendocrinology (2016) 103 (1): 86–95.
Published Online: 29 January 2015
...Kim M.J.A. Claessen; Gherardo Mazziotti; Nienke R. Biermasz; Andrea Giustina Acromegaly is a chronic, progressive disease caused by a growth hormone (GH)-producing pituitary adenoma, resulting in elevated GH and insulin-like growth factor 1 concentrations. Following appropriate therapy (surgery...
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Journal Articles
Neuroendocrinology (2016) 103 (1): 7–17.
Published Online: 05 January 2015
... the discovery of growth hormone (GH) and insulin-like growth factor I (IGF-I) and after demonstrating an association with GH hypersecretion and elevated circulating IGF-I. From the beginning of the 20th century, acromegaly could be treated by pituitary surgery and/or radiotherapy. After 1970, medical therapies...
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Journal Articles
Neuroendocrinology (2012) 95 (3): 257–266.
Published Online: 07 February 2012
...R. Torronteras; A. Canalejo; F. Elsaesser The aim of this study was to assess the ontogenetic changes in vitro in both the responsiveness of anterior pituitary tissue to growth hormone-releasing hormone (GHRH) and the critical role of GHRH in the long-term regulation of pulsatile GH secretion...
Journal Articles
Neuroendocrinology (2011) 94 (1): 66–74.
Published Online: 05 April 2011
...Elisabetta Verrillo; Carla Bizzarri; Marco Cappa; Oliviero Bruni; Martino Pavone; Raffaele Ferri; Renato Cutrera Background/Aims: Growth hormone (GH) is preferentially secreted during slow wave sleep and the interactions between human sleep and the somatotropic system are well documented, although...
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