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1-20 of 406
Keywords: Growth hormone
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Journal Articles
Junjun Li, Hao Song, Ting Chen, Sixi Zhang, Chao Zhang, Chen Ma, Lingye Zhang, Tengfei Wang, Yuan Qian, Xingli Deng
Journal:
Neuroendocrinology
Neuroendocrinology (2024) 114 (6): 589–601.
Published Online: 02 April 2024
...Junjun Li; Hao Song; Ting Chen; Sixi Zhang; Chao Zhang; Chen Ma; Lingye Zhang; Tengfei Wang; Yuan Qian; Xingli Deng Introduction: Growth hormone (GH) secreting pituitary adenoma is considered one of the most harmful types of Pituitary Neuroendocrine Tumors (PitNETs). Our previous research has found...
Journal Articles
Alexandra Labarthe, Philippe Zizzari, Oriane Fiquet, Nicolas Lebrun, Johannes D. Veldhuis, Ferdinand Roelfsema, Christophe Chauveau, Mohammad Bohlooly-Y, Jacques Epelbaum, Virginie Tolle
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (3): 215–234.
Published Online: 08 March 2022
.... 2021 Ghrelin Growth hormone secretagogue receptor signaling Growth hormone Meal pattern Sexual dimorphism Ghrelin, a 28 amino acid octanoylated peptide hormone predominantly secreted by the enteroendocrine cells in the stomach, is a potent growth hormone (GH) secretagogue...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (7): 673–701.
Published Online: 27 July 2021
... oscillations in body core tissues turnover. Specifically, we discuss potential underlying mechanisms linking sleep to body composition, both during rest and under challenging conditions. Among other described pathways, we highlight the possible role of the growth hormone that was found to be involved...
Journal Articles
Yi Yuen Wang, Mueez Waqar, Ahmed Abou-Zeid, Tara Kearney, Carmela Caputo, Julian Davis, Peter Trainer, Claire Higham, Federico Roncaroli, Kanna K. Gnanalingham
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (4): 345–357.
Published Online: 28 May 2021
... expertise. We studied the value of early post-operative growth hormone (GH) level as a predictor of outcome and to guide early surgical re-exploration for residual disease in patients with acromegaly. Methods: Patients with acromegaly undergoing first-time endoscopic transsphenoidal surgery between 2005...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (3): 276–286.
Published Online: 26 April 2021
... of sellar tumours [3]. Lactotroph and some growth hormone (GH)-secreting tumours can respond to medical therapy [4]. Surgery is the treatment of choice for clinically non-functioning tumours [5]. The role of MRI in predicting the endocrine status of adenohypophyseal tumours is not clear, with studies...
Journal Articles
Marina Caputo, Chiara Mele, Alice Ferrero, Ilaria Leone, Tommaso Daffara, Paolo Marzullo, Flavia Prodam, Gianluca Aimaretti
Journal:
Neuroendocrinology
Neuroendocrinology (2022) 112 (1): 1–14.
Published Online: 15 January 2021
..., such as growth hormone (GH) and gonadal hormones, and the increase in the synthesis of hormones with catabolic properties such as cortisol, as shown in Figure 1 . These adaptations go in parallel with an increase in pituitary-related diseases due to the higher life expectancy. In the literature, the age-related...
Journal Articles
Valentina Gasco, Alice Ferrero, Alessandro Bisceglia, Nunzia Prencipe, Valeria Cambria, Fabio Bioletto, Ezio Ghigo, Mauro Maccario, Silvia Grottoli
Journal:
Neuroendocrinology
Neuroendocrinology (2021) 111 (5): 442–450.
Published Online: 24 April 2020
...Valentina Gasco; Alice Ferrero; Alessandro Bisceglia; Nunzia Prencipe; Valeria Cambria; Fabio Bioletto; Ezio Ghigo; Mauro Maccario; Silvia Grottoli Introduction: The diagnosis of growth hormone deficiency (GHD) in adults is based on a reduced GH response to provocative tests, such as the insulin...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2019) 108 (3): 244–255.
Published Online: 25 January 2019
...Mirella Hage; Peter Kamenický; Philippe Chanson The exact physiological basis of acute growth hormone (GH) suppression by oral glucose is not fully understood. Glucose-mediated increase in hypothalamic somatostatin seems to be the most plausible explanation. Attempts to better understand its...
Journal Articles
Olaya Fernández-Gayol, Paula Sanchis, Kevin Aguilar, Alicia Navarro-Sempere, Gemma Comes, Amalia Molinero, Mercedes Giralt, Juan Hidalgo
Journal:
Neuroendocrinology
Neuroendocrinology (2019) 109 (2): 113–130.
Published Online: 13 January 2019
... were group-housed, it was not possible to discard those animals with peripheral recombination ( n = 5–7 cages). Serum triglyceride and cholesterol levels were analyzed using Cromatest kits (Linear Chemicals S.L.). Serum insulin, leptin, and growth hormone (GH) levels were measured using ELISA kits...
Journal Articles
Sanne E. Franck, Federico Gatto, Aart Jan van der Lely, Joseph A.M.J.L. Janssen, Alof H.G. Dallenga, A. Paul Nagtegaal, Leo J. Hofland, Sebastian J.C.M.M. Neggers
Journal:
Neuroendocrinology
Neuroendocrinology (2017) 105 (1): 44–53.
Published Online: 25 July 2016
...Sanne E. Franck; Federico Gatto; Aart Jan van der Lely; Joseph A.M.J.L. Janssen; Alof H.G. Dallenga; A. Paul Nagtegaal; Leo J. Hofland; Sebastian J.C.M.M. Neggers Background: Growth hormone-secreting pituitary adenomas (somatotroph adenoma) predominantly express somatostatin receptors (SSTRs...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2015) 102 (4): 288–299.
Published Online: 29 May 2015
.... Similar to Nrg1α, Nrg1β increased the prolactin (PRL) expression in rat pituitary RC-4B/C cells, which can be inhibited by an Akt inhibitor. In addition, Nrg1β had no apparent effect on growth hormone expression at the mRNA or protein levels. Collectively, we conclude that hypothalamic Nrg1 may...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2016) 103 (1): 50–58.
Published Online: 12 February 2015
...Philippe Chanson Treatment of acromegaly aims to correct (or prevent) tumor compression of surrounding tissues by excising the disease-causing lesion and reduce growth hormone (GH) and IGF-1 levels to normal values. When surgery (the usual first-line treatment) fails to correct GH/IGF-1...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2016) 103 (1): 66–74.
Published Online: 30 January 2015
...John McCabe; John Ayuk; Mark Sherlock Acromegaly is a rare condition characterized by excessive secretion of growth hormone (GH), which is almost always due to a pituitary adenoma. Acromegaly is associated with significant morbidity such as hypertension, type 2 diabetes, cardiomyopathy, obstructive...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2016) 103 (1): 86–95.
Published Online: 29 January 2015
...Kim M.J.A. Claessen; Gherardo Mazziotti; Nienke R. Biermasz; Andrea Giustina Acromegaly is a chronic, progressive disease caused by a growth hormone (GH)-producing pituitary adenoma, resulting in elevated GH and insulin-like growth factor 1 concentrations. Following appropriate therapy (surgery...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2016) 103 (3-4): 197–206.
Published Online: 09 January 2015
...Nicoleta C. Olarescu; Ansgar Heck; Kristin Godang; Thor Ueland; Jens Bollerslev Background/Aims: Adipose tissue (AT) distribution is closely related to metabolic disease risk. Growth hormone (GH) reduces visceral and total body fat mass and induces whole-body insulin resistance. Our aim...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2016) 103 (1): 7–17.
Published Online: 05 January 2015
... the discovery of growth hormone (GH) and insulin-like growth factor I (IGF-I) and after demonstrating an association with GH hypersecretion and elevated circulating IGF-I. From the beginning of the 20th century, acromegaly could be treated by pituitary surgery and/or radiotherapy. After 1970, medical therapies...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2013) 97 (3): 203–211.
Published Online: 25 August 2012
...Alfhild Grönbladh; Jenny Johansson; Fred Nyberg; Mathias Hallberg The beneficial effects of growth hormone (GH) on memory and learning have previously been confirmed in both humans and in animal models. An important role of GABA B receptors for multiple forms of learning and memory has also been...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2012) 95 (3): 257–266.
Published Online: 07 February 2012
...R. Torronteras; A. Canalejo; F. Elsaesser The aim of this study was to assess the ontogenetic changes in vitro in both the responsiveness of anterior pituitary tissue to growth hormone-releasing hormone (GHRH) and the critical role of GHRH in the long-term regulation of pulsatile GH secretion...
Journal Articles
Elisabetta Verrillo, Carla Bizzarri, Marco Cappa, Oliviero Bruni, Martino Pavone, Raffaele Ferri, Renato Cutrera
Journal:
Neuroendocrinology
Neuroendocrinology (2011) 94 (1): 66–74.
Published Online: 05 April 2011
...Elisabetta Verrillo; Carla Bizzarri; Marco Cappa; Oliviero Bruni; Martino Pavone; Raffaele Ferri; Renato Cutrera Background/Aims: Growth hormone (GH) is preferentially secreted during slow wave sleep and the interactions between human sleep and the somatotropic system are well documented, although...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2011) 93 (4): 259–264.
Published Online: 01 April 2011
...Hae Sang Lee; Jin Soon Hwang Background: The diagnosis of growth hormone (GH) deficiency is based on a reduced peak GH response to provocative tests. However, the provocative tests are poorly reproducible and GH secretion is regulated by physiological parameters, such as body weight and puberty...
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