... hormone (GnRH). A link between nutrition and reproductive function is well established. In this study we investigated the effects of two peptides associated with appetite control, galanin and leptin, on the regulation of LH release from the pituitary. Methods: Using perifused anterior pituitary tissue...

...-positive responses may occur in patients with diabetes mellitus. Galanin has previously been demonstrated to induce paradoxical inhibition of growth hormone (GH) secretion in most patients with active acromegaly. In this study, we assessed GH response to galanin infusion in a series of 17 consecutive...

...Barbara Planas; Pamella E. Kolb; Murray A. Raskind; Margaret A. Miller The neuropeptide galanin (GAL) has been implicated in a variety of neuroendocrine functions and has been shown to be regulated by gonadal hormones in several brain regions. We have used slice binding and quantitative...

...Youssef Anouar; Lee E. Eiden Expression of the neuropeptide galanin in the adrenal gland is rapidly induced by reflex stimulation of the splanchnic nerve following insulin-induced hypoglycemia. Here, we examine the cellular localization and mechanism of galanin mRNA upregulation in the adrenal...

... or malnutrition. A reasonable hypothesis for this occurrence is the alteration of somatostatin and GH-releasing hormone (GHRH) synthesis, storage and secretion. In this study, we investigated the effects of food deprivation on GH, GHRH, hypothalamic and pituitary galanin (GAL), and somatostatin through...

...Chilung Tang; Akira Akabayashi; Andre Manitiu; Sarah F. Leibowitz The peptide galanin (GAL) exists in dense concentrations within the medial hypothalamus and is synthesized in a population of neurons within the paraventricular nucleus (PVN). This peptide has been linked to energy homeostasis...

...Mario Baratta; Roberta Saleri; Cristina Mascadri; David H. Coy; Andres Negro-Vilar; Carlo Tamanini; Andrea Giustina Galanin is widely distributed in the peripheral and central nervous system and has been indicated as a putative hypothalamic-hypophysiotropic hormone. This study was performed...

...Ettore Ciro degli Uberti; Marta Bondanelli; Angelo Margutti; Maria Rosaria Ambrosio; Alberto Valentini; Michela Campo; Paola Franceschetti; Maria Chiara Zatelli; Raffaele Pansini; Giorgio Trasforini The neuropeptide galanin (GAL) is widely distributed in the central and peripheral nervous systems...

... immunoreactivity, both in vasopressin and oxytocin neurons. Using in situ hybridization and immunohistochemistry we have also investigated the expression of the mRNAs for oxytocin, dynorphin, galanin and galanin message-associated peptide and of oxytocin and dynorphin in the PVN of lactating and nonlactating rats...

... (GHRH) and somatostatin (SRIH). At the level of the hypothalamus, both galanin (GAL) and neuropeptide Y (NPY) are thought to regulate the secretion of the above releasing and inhibiting factors. Both peptides are also potent orexigenic agents. We have studied ovariectomised ewes that were either well...

...Maria Vrontakis; Antonio Torsello; Valeriano Leite; Jean-Claude Vuille; Hong Zhang Galanin is a 29 amino acid neuropeptide widely distributed throughout the mammalian nervous and endocrine system. We have previously reported that estrogen dramatically increases galanin gene expression and protein...

...Robert Drouhault; Nathalie-Colette Guérineau; Patrice Mollard; Marie-Anne Cadoret; Jean-Benoit Corcuff; Anne-Marie Vacher; Nidaravone Vilayleck Galanin is widely distributed throughout the rat neural and endocrine system with the highest concentration in the anterior pituitary. The effects...

...Philippe L. Selvais; Evelyne Adam; Ides M. Colin; Joséphine Z. Kasa-Vubu; Jean-François Denef; Dominique M. Maiter To investigate whether pituitary-dependent hormones may regulate galanin (GAL) content, synthesis and distribution in the hypothalamus, female hypophysectomized Wistar rats were...

...Philippe L. Selvais; Ides M. Colin; Evelyne Adam; Joséphine Z. Kasa-Vubu; Jean-François Denef; Dominique M. Maiter To understand better the relationship between hypothalamic galaninergic neurons and the pituitary gland, we studied the effects of hypophysectomy on hypothalamic galanin (GAL) content...

...Chaya Gopalan; Ye Tian; Kenneth E. Moore; Keith J. Lookingland The purpose of the present study was to examine the effects of galanin on the basal and stimulated activity of tuberoinfundibular dopaminergic (TIDA) neurons in male and female rats. TIDA neuronal activity was estimated by measuring...

...Kunikazu Kondo; Takashi Murase; Kazuo Otake; Masafumi Ito; Fumihiko Kurimoto; Yutaka Oiso Previous neuroanatomical studies have revealed a localization of galanin in several nuclei in the brain stem which are involved in the hemodynamic control of arginine vasopressin (AVP) release. The present...

... eminence. We have measured neuropeptide Y(NPY), substance P (SP), galanin (GAL), neurokinin A (NKA), peptide histidine isoleucine (PHI), vasoactive intestinal peptide (VIP), neurotensin (NT) and cholecystokinin (CCK). We also examined the sheep median eminence using immunohistochemistry for NPY, SP and GAL...

...Andrea Giustina; Massimo Licini; Angela Girelli; Anna Rosa Bussi; William B. Wehrenberg Glucocorticoids are known to decrease growth hormone (GH) secretion in man. Galanin, a 29-amino acid peptide, and arginine stimulate GH secretion through different hypothalamic mechanisms. The aim of our study...

...), corticotropin-releasing hormone (CRH), galanin (GAL), enkephalin (ENK), neurotensin (NT), vasoactive intestinal polypeptide (VIP) and vasopressin (VP). GAL mRNA was also analyzed in the anterior paraventricular, arcuate, and dorsomedial nuclei of the hypothalamus. At the PVN level, a feedback effect of thyroid...

...Luciana Giardino; Antonino Velardo; Andrea Gallinelli; Laura Calzà In this paper we describe the modification of the galanin (GAL)-like immunostaining in the hypothalamus of rats, which were made hypothyroid at 52 days after birth. On 21st day after the surgical ablation of the thyroid gland...