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Keywords: GT1–7 cells
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Journal Articles
Neuroendocrinology (2012) 96 (2): 162–171.
Published Online: 08 June 2012
... of intracellular signaling pathways (i.e. nonclassical actions). The mPRs are highly expressed in the brain, but research on their neural functions has only been conducted in a single neuronal cell line, GT17 cells, which have negligible nuclear progesterone receptor (PR) expression. GT17 cells express mPRα...
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Neuroendocrinology (2007) 84 (6): 353–363.
Published Online: 30 March 2007
.... Orexin-1 receptor (OX1R) expression was detected in GT1-7 cells by RT-PCR and Western blot. Results showed that 0.1–1 n M orexin A, when administered in culture media for 4 h, can significantly stimulate GnRH mRNA expression in GT1-7 cells (p < 0.05). Administration of 1 µ M OX1R antagonist, SB-334867...
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Neuroendocrinology (1999) 70 (4): 246–254.
Published Online: 14 October 1999
... receptor types I, IB, and II. We examined the effects of activin A on GnRH protein secretion and mRNA levels in GT1-7 cells. Treatment with rh-activin A regulated both GnRH protein secretion and GnRH mRNA expression in the GT1-7 cells in a time-dependent fashion. Using transient transfection assays, we...
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