...–11 mice. To accommodate intensive behavioral testing, mice were tested in cohorts. A total of 11 cohorts with 8–15 mice each completed the study. Experimental conditions were balanced within cohorts. Eicosapentaenoic acid Diet-induced obesity Alzheimer’s disease Corticosterone Behavior...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Lcn2 Appetite Sex difference Diet-induced obesity Adiponectin Estradiol Currently, obesity is rising greatly worldwide, increasing the risk of death from many...

... from diet-induced obesity and type 2 diabetes (T2D). In addition, a high-caloric diet was combined with running wheel exercise to test the interaction of diet and exercise. HFD was obesogenic in both genotypes, but α 2A –/– mice accumulated less visceral fat than the wild-type controls, were protected...

... in the hypothalamus during the development of diet-induced obesity. Additionally, our recent work suggests that suppressor of cytokine signaling-3 negatively regulates the PI3K pathway of leptin signaling in the hypothalamus, a mechanism expected to play a significant role in diet-induced obesity. Together, the PI3K...

... during prolonged negative energy balance. We discuss the idea that the metabolic status plays a key role in ghrelin function. For example, our recent studies illustrate that diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons. On the other side of the metabolic coin, ghrelin...