... that explore the effects of thyroid status modulation on other hormonal axes remain scarce. We aimed to determine the effects of thyroid status modulation on prolactin, IGF-1, cortisol, LH, testosterone, and SHBG levels. We also explored whether effects differed depending on type of challenge, sex...

... corticosteroid hormone production, the bioavailability of corticosteroid hormones and especially corticosteroid-binding globulin capacity, and glucocorticoid receptor function. The effect of single mutations may be dependent on the genetic background, and genetic variation of cortisol levels may have different...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Memory Metabolism Cortisol 11β-hydroxysteroid dehydrogenase Hippocampus Diabetes is defined...

... examination confirmed ACTH secreting tumour in both of the patients. As IPSS is not available in Iceland, international co-operation is of great importance. All patients needing IPSS were sent to Sahlgrenska University Hospital in Gothenburg during this 10-year period (7 patients). Serum cortisol (SeC...

...Hewei Cheng; Lu Gao; Rixing Jing; Bo Hou; Xiaopeng Guo; Yong Yao; Ming Feng; Bing Xing; Feng Feng; Yong Fan Introduction: Chronic exposure to excessive endogenous cortisol leads to brain changes in Cushing’s disease (CD). However, it remains unclear how CD affects large-scale functional networks...

...Mendel Castle-Kirszbaum; Tony Goldschlager; Margaret D Y Shi; Peter J Fuller Water balance is fundamental to all homeostasis. The hypothalamic-pituitary-adrenal axis influences water balance through the effects of corticotropin-releasing hormone and cortisol on arginine vasopressin secretion...

.... Two sets of saliva samples were consecutively collected from patients before (pre-T1) and 1 week after (post-T1) the first TKA ( n = 69). HPA axis function was analyzed in a subgroup of 20 patients with a typical cortisol awakening response (CAR) in both the sets of saliva samples. Results: Surgery...

... in response to an acute light exposure, a protocol that freezes the larvae in response to the light stimulus. To test whether cortisol signalling is involved in the stress-mediated hyperactivity, we treated wildtype fish with metyrapone (MET), an inhibitor of 11β-hydroxylase, to suppress cortisol production...

...Valentina Gasco; Chiara Bima; Alice Geranzani; Jacopo Giannelli; Lorenzo Marinelli; Chiara Bona; Valeria Cambria; Alessandro Maria Berton; Nunzia Prencipe; Ezio Ghigo; Mauro Maccario; Silvia Grottoli Introduction: According to guidelines, a morning serum cortisol level <83 nmol/L is diagnostic...

...Bernard J. Carroll; James C. Ritchie; Hollister Rogers; Doh Kwan Kim Background: Using high-frequency blood sampling, we demonstrate glucocorticoid fast feedback (FF) mediated by endogenous cortisol in 6 normal humans. Methods: We stimulated adrenocorticotropic hormone (ACTH) secretion by ovine...

... various tests which only capture short-term cortisol exposure, whereas patients with endogenous CS generally have elevated cortisol levels over longer periods of time. Scalp hair assessment has emerged as a convenient test in capturing glucocorticoid concentrations over long periods of time. The aim...

..., and post-stress ACTH - but not cortisol - concentrations. Also, suppression of ACTH by 3 mg dexamethasone was impaired in the athletes compared to the control subjects, while the ACTH and cortisol response to additional CRH did not differ between the 2 groups. Finally, long-term verbal memory was impaired...

... significance, further studies should systematically examine which dosages of fludrocortisone are associated with optimal cognitive function and mood in AI patients. Addison’s disease Cognition Cortisol Mineralocorticoid and glucocorticoid receptor Primary adrenal insufficiency Fludrocortisone Mood...

... corticosteroid levels on subsequent cardiovascular responses. In the current study, we have examined the effects of both birth weight and maternal cortisol levels in a cohort of mothers and their pre-adolescent children. Procedure: A total of 216 women and their 7- to 9-year-old children comprised the cohort...

... whether HPA system activity is related to body weight and composition in depressed inpatients. Methods: In a cohort of 51 female and 20 male depressed inpatients, we measured saliva cortisol (HPA system activity), body mass index (BMI), waist circumference as well as body composition as reflected...

... by hypothalamic activity. Objective: To evaluate plasma BDNF concentration in patients with functional hypothalamic amenorrhea (FHA), with reference to the BDNF circadian rhythm and its relation with the cortisol (F) rhythm, and to assess whether the duration of amenorrhea might influence the BDNF:F ratio in FHA...

..., and intensities all place significant burden on the HPA axis and its ability to properly regulate the glucocorticoid dynamics [ 20,21 ]. Specifically, activation of the HPA axis by perception and experience of the stressor typically leads to the production and release of the glucocorticoid cortisol, which...

...Jamie M. Zeitzer; Bita Nouriani; Eric Neri; David Spiegel Introduction: The ‘diurnal slope' of salivary cortisol has been used as a measure of stress and circadian function in a variety of reports with several detailing its association with cancer progression. The relationship of this slope...

... of MDMA (125 mg), methylphenidate (60 mg), MDMA + methylphenidate, and placebo on 4 separate days using a cross-over study design. Cortisol, cortisone, corticosterone, 11-dehydrocorticosterone, aldosterone, 11-deoxycorticosterone, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEAS...

... assays for total plasma P and cortisol were done in a sample of 18 healthy men. Results: Plasma P levels explained up to 65% of the variability in 5-HT 1A receptor binding in limbic regions including the amygdala, orbitofrontal cortex and retrosplenial cortex. When controlling for cortisol in the model...