...Jasmin Ewert; Maximilian Seidl; Jann Achim Hommen; Matthias Schott; Norbert Gattermann Background: Adrenocorticotropic hormone (ACTH) and corticotropin-releasing hormone (CRH) are essential regulators of cortisol production within the hypothalamic-pituitary-adrenal (HPA) axis. Elevated cortisol...

...Weigang Cai; Michaela Egertová; Cleidiane G. Zampronio; Alexandra M. Jones; Maurice R. Elphick Background: Corticotropin-releasing hormone (CRH) mediates physiological responses to stressors in mammals by triggering pituitary secretion of adrenocorticotropic hormone, which stimulates adrenal...

...Erin Faught; Mathilakath M. Vijayan Introduction: The stress response mediated by the hypothalamus-pituitary-adrenal (HPA) axis activation is highly conserved in vertebrates. Hyperactivity is one such established acute stress response, and corticotropin-releasing hormone (CRH), the primary step...

... to responses to corticotropin-releasing hormone (CRH). We assessed the ability of ghrelin to enhance ACTH and cortisol responses when added to CRH stimulation in CD patients. Methods: In 21 CD patients (18 females, 3 males; age 49.8 ± 10.2 years; BMI 29.8 ± 0.8) and 8 healthy subjects (7 females, 1 male; age...

...Carlo Contoreggi; Kenner C. Rice; George Chrousos Overproduction of corticotropin-releasing hormone (CRH) and stress system abnormalities are seen in psychiatric diseases such as depression, anxiety, eating disorders, and addiction. Investigations of CRH type 1 receptor (CRHR1) nonpeptide...

... serum cortisol concentrations were obtained (n = 78) and corticotropin-releasing hormone (CRH) (n = 53) and metyrapone tests (n = 72) were performed. Three groups of outcome were identified: sustained remission, early failure (persistent CD), and late relapse. Results: Immediate postoperative remission...

...Constantinos Simopoulos; Eirini Christodoulou; Maria Lambropoulou; Alexandra K. Tsaroucha; Stylianos Kakolyris; Alexandros Polychronidis; Athanassios J. Karayiannakis; Ekaterini Chatzaki The corticotropin-releasing hormone (CRH) system, consisting of CRH, urocortins (Ucns), their receptors CRH 1...

... are hyperactivated in major depressed patients. This hyperactivity might be causally related to at least part of the symptomatology of depression. 3 02 1994 27 05 1994 9 4 2008 Corticotropin-releasing hormone Immunocytochemistry Human Hypothalamus Paraventricular nucleus Hypothalamo...

... antagonism prevents hypoglycemia-induced LH suppression suggests that vasopressin is a physiological inhibitor of LH secretion in the rhesus monkey. Stress Gonadotropin Vasopressin Corticotropin-releasing hormone Hypoglycemia Rhesus monkey © 1994 S. Karger AG, Basel 1994 Copyright / Drug...

...Aldo E. Calogero; Robertus F.A. Weber; Francesco Raiti; Nunziatina Burrello; Maira Lusia Moncada; Alessandro Mongioì; Rosario D’Agata Corticotropin-releasing hormone (CRH) has been shown capable of inhibiting hypothalamic gonadotropin-releasing hormone (GnRH) release through activation...

... but 1 horse, sampling occurred during the broad circadian maximum in plasma cortisol concentrations. Concentrations of corticotropin-releasing hormone (CRH; n = 7 horses), arginine vasopressin (AVP), ACTH and cortisol were measured by radioimmunoassay. In all horses, CRH, AVP and ACTH secretion patterns...

... Cushing’s disease Corticotropin-releasing hormone Clinical neuroendocrinology Corticotropin Regulation and Corticoid Feedback Neuroendocrinology 1994;60:237-242 Marco BOscaro* Annalisa Rampazzoa Agostino Paolettaa Massimo Scanarinib Piera Belluardoa Francesco Falloa Nicoletta Soninoa a Division...

... in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis function in concert with the physiological activator of the axis, hypothalamic corticotropin-releasing hormone (CRH). We examined the effects of AVP and/or three synthetic V 1b receptor antagonists on the activity of the HPA axis in vivo...

... the inhibitory effect of hypoglycemia on LH secretion in sheep and rat. The objective of the present study was to determine if corticotropin-releasing hormone (CRH) and endogenous opiates are involved in the LH response to hypoglycemia in the nonhuman primate. Blood samples were collected at 15-min intervals...

...Gábor Légrádi; David Holzer; Leonard P. Kapcala; Ronald M. Lechan The corticotropin-releasing hormone (CRH) gene contains a perfect palindromic motif in its promoter region that allows binding of the cyclic adenosine monophosphate response element binding protein, CREB. Since previous studies...

... and corticosterone levels were also significantly reduced in the SR48692-implanted animals. This suggests that the inhibitory effects of SR48692 were restricted to periods of stimulated HPA activity. A decrease in corticotropin-releasing hormone (CRH)-like immunoreactivity was observed within the PVN following...

... of THC to inhibit LH release, female rats were either pretreated with the corticotropin-releasing hormone (CRH) receptor antagonist, α-helical CRH, or were adrenalectomized prior to acute THC administration, in order to assess the roles of CRH and corticosterone in the ability of THC to suppress LH...

..., whereas in transgenic animals only a short-lasting decrease in ACTH levels was apparent. Corticotropin-releasing hormone (CRH) administration resulted in an enhanced response in plasma ACTH levels in transgenic mice, whereas the corticosterone response was markedly reduced. The discrepancy between ACTH...

..., instructions or products referred to in the content or advertisements. Nitric oxide Carbon monoxide Gonadotropin-releasing hormone Gonadotropins Corticotropin Corticotropin-releasing hormone Growth hormone Growth hormone-releasing hormone Prolactin Neuroimmune interactions Folliculo-stellate...

...Sieglinde Modell; Alexander Yassouridis; Johannes Huber; Florian Holsboer Decreased feedback control of the hypothalamic-pituitary-adrenocortical (HPA) system as revealed by the combined dexamethasone and corticotropin-releasing hormone (DEX-CRH) test has been documented in the vast majority...