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1-17 of 17
Keywords: Chromogranin A
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Journal Articles
Mark J.C. van Treijen, Dennis van der Zee, Birthe C. Heeres, Femke C.R. Staal, Menno R. Vriens, Lisette J. Saveur, Wieke H.M. Verbeek, Catharina M. Korse, Monique Maas, Gerlof D. Valk, Margot E.T. Tesselaar
Journal:
Neuroendocrinology
Neuroendocrinology (2021) 111 (6): 586–598.
Published Online: 03 June 2020
... gastroenteropancreatic neuroendocrine tumors (GEP-NETs). The aim of the study was to validate the NETest®, a blood molecular genomic analysis, for predicting the course of disease in individual patients compared to chromogranin A (CgA). NETest® score (normal ≤20%) and CgA level (normal <100 µg/L) were measured in 152...
Journal Articles
Anna Malczewska, Magdalena Witkowska, Monika Wójcik-Giertuga, Katarzyna Kuśnierz, Agnes Bocian, Agata Walter, Mateusz Rydel, Amanda Robek, Sylwia Pierzchała, Magdalena Malczewska, Izabela Leś-Zielińska, Damian Czyżewski, Dariusz Ziora, Joanna Pilch-Kowalczyk, Wojciech Zajęcki, Beata Kos-Kudła
Journal:
Neuroendocrinology
Neuroendocrinology (2021) 111 (4): 304–319.
Published Online: 24 April 2020
... with chromogranin A (CgA) measurement. Methods: The cohorts were: gastroenteropancreatic NEN (GEP-NEN; n = 253), bronchopulmonary NEN (BPNEN; n = 64), thymic NEN ( n = 1), colon cancer ( n = 37), non-small-cell lung cancer (NSCLC; n = 63), benign lung disease ( n = 59), and controls ( n = 86). In the GEPNEN group...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (3-4): 198–216.
Published Online: 10 March 2020
... of biomarkers. Chromogranin A (CgA), the default neuroendocrine tumor biomarker, has undergone wide assessment in gastroenteropancreatic neuroendocrine tumors. Objectives: To evaluate CgA in lung NEN, define its clinical utility as a biomarker, assess its diagnostic, prognostic, and predictive efficacy, as well...
Journal Articles
Gitte Dam, Henning Grønbæk, Halfdan Sorbye, Espen Thiis Evensen, Björn Paulsson, Anders Sundin, Claus Jensen, Dyveke Ebbesen, Ulrich Knigge, Eva Tiensuu Janson
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (3-4): 217–224.
Published Online: 02 October 2019
...Gitte Dam; Henning Grønbæk; Halfdan Sorbye; Espen Thiis Evensen; Björn Paulsson; Anders Sundin; Claus Jensen; Dyveke Ebbesen; Ulrich Knigge; Eva Tiensuu Janson Background: Retrospective studies are conflicting but most of them report that an increase in plasma chromogranin A (CgA) predicts tumor...
Journal Articles
Somer Matar, Anna Malczewska, Kjell Oberg, Lisa Bodei, Harry Aslanian, Anna Lewczuk-Myślicka, Pier Luigi Filosso, Alejandro L. Suarez, Agnieszka Kolasińska-Ćwikła, Matteo Roffinella, Beata Kos-Kudła, Jarosław B. Ćwikła, Ignat A. Drozdov, Mark Kidd, Irvin M. Modlin
Journal:
Neuroendocrinology
Neuroendocrinology (2020) 110 (3-4): 185–197.
Published Online: 16 April 2019
... of circulating tumor markers for clinical management in bronchopulmonary (BP) neuroendocrine tumors/neoplasms (NET/NEN) is of considerable clinical interest. Chromogranin A (CgA), a “universal” NET biomarker, is considered controversial as a circulating biomarker of BPNEN. Aim: Assess utility of CgA...
Journal Articles
Noora Karppinen, Riikka Lindén, Harri Sintonen, Maija Tarkkanen, Risto Roine, Ilkka Heiskanen, Niina Matikainen, Camilla Schalin-Jäntti
Journal:
Neuroendocrinology
Neuroendocrinology (2019) 107 (4): 366–374.
Published Online: 05 October 2018
... as that of the patients. Health-related quality of life Small intestine neuroendocrine tumor Carcinoid syndrome Depression Diarrhea 5-Hydroxyindoleacetic acid Chromogranin A Small intestine neuroendocrine tumors (SI-NETs) arise from neuroendocrine cells in the jejunum or ileum and typically secrete...
Journal Articles
Ivan Kruljac, Ivan Vičić, Kristina Blaslov, Zorica Kolak, Martina Benković, Davor Kust, Blaženka Ladika Davidović, Gordan Tometić, Ivan Penavić, Nina Dabelić, Ljubica Vazdar, Tajana Pavić, Milan Vrkljan
Journal:
Neuroendocrinology
Neuroendocrinology (2018) 107 (3): 284–291.
Published Online: 16 August 2018
...Ivan Kruljac; Ivan Vičić; Kristina Blaslov; Zorica Kolak; Martina Benković; Davor Kust; Blaženka Ladika Davidović; Gordan Tometić; Ivan Penavić; Nina Dabelić; Ljubica Vazdar; Tajana Pavić; Milan Vrkljan Background: Serum chromogranin A (CgA) is routinely used as a biomarker in patients...
Journal Articles
Kjell Oberg, Anne Couvelard, Gianfranco Delle Fave, David Gross, Ashley Grossman, Robert T. Jensen, Ulrich-Frank Pape, Aurel Perren, Guido Rindi, Philippe Ruszniewski, Jean-Yves Scoazec, Staffan Welin, Bertram Wiedenmann, Diego Ferone, all other Antibes Consensus Conference participants
Journal:
Neuroendocrinology
Neuroendocrinology (2017) 105 (3): 201–211.
Published Online: 08 April 2017
... ones so far have been chromogranin A and neuron-specific enolase (NSE). Chromogranin A is the most important general biomarker for most NETs with a sensitivity and specificity somewhere between 60 and 90%. NSE has been a relevant biomarker for patients with high-grade tumors, particularly lung...
Journal Articles
U. Knigge, J. Capdevila, D.K. Bartsch, E. Baudin, J. Falkerby, R. Kianmanesh, B. Kos-Kudla, B. Niederle, E. Nieveen van Dijkum, D. O'Toole, A. Pascher, N. Reed, A. Sundin, M.-P. Vullierme, all other Antibes Consensus Conference participants
Journal:
Neuroendocrinology
Neuroendocrinology (2017) 105 (3): 310–319.
Published Online: 17 February 2017
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Neuroendocrine neoplasm Neuroendocrine tumor Neuroendocrine carcinoma Follow-up TNM staging Chromogranin A Neuron-specific enolase 5-Hydroxyindoleacetic acid NT-pro-brain...
Journal Articles
Sara Massironi, Roberta Elisa Rossi, Giovanni Casazza, Dario Conte, Clorinda Ciafardini, Marianna Galeazzi, Maddalena Peracchi
Journal:
Neuroendocrinology
Neuroendocrinology (2015) 100 (2-3): 240–249.
Published Online: 18 November 2014
...Sara Massironi; Roberta Elisa Rossi; Giovanni Casazza; Dario Conte; Clorinda Ciafardini; Marianna Galeazzi; Maddalena Peracchi Background/Aims: Plasma chromogranin A (CgA) is the most widely used biochemical biomarker in the diagnostic workup and follow-up of gastroenteropancreatic neuroendo- crine...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2015) 100 (4): 265–277.
Published Online: 02 October 2014
.... Neuroendocrine disease represents an area of dire biomarker paucity since the individual biomarkers (gastrin, insulin, etc.) are not widely applicable to the diverse types of neuroendocrine neoplasia. Broad-spectrum markers such as chromogranin A have limitations in sensitivity, specificity and reproducibility...
Journal Articles
S. Grozinsky-Glasberg, K.I. Alexandraki, D. Barak, V. Doviner, P. Reissman, G.A. Kaltsas, D.J. Gross
Journal:
Neuroendocrinology
Neuroendocrinology (2013) 98 (1): 31–37.
Published Online: 22 November 2012
... Tumor Society criteria for RHC, residual disease may be missed in 18% of ANET patients. All specimens were reviewed by a pathologist with experience in neuroendocrine tumors at each contributing institution. Sections were immunostained for chromogranin, neuron-specific enolase (NSE), synaptophysin...
Journal Articles
Wen-Chi Chou, Yu-Shin Hung, Jun-Te Hsu, Jen-Shi Chen, Chang-Hsien Lu, Tsann-Long Hwang, Kun-Ming Rau, Kun-Yun Yeh, Tse-Ching Chen, Chien-Feng Sun
Journal:
Neuroendocrinology
Neuroendocrinology (2012) 95 (4): 344–350.
Published Online: 14 February 2012
...Wen-Chi Chou; Yu-Shin Hung; Jun-Te Hsu; Jen-Shi Chen; Chang-Hsien Lu; Tsann-Long Hwang; Kun-Ming Rau; Kun-Yun Yeh; Tse-Ching Chen; Chien-Feng Sun Purpose: To evaluate the significance of plasma chromogranin A (CgA) levels in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NET...
Journal Articles
Staffan Welin, Mats Stridsberg, Janet Cunningham, Dan Granberg, Britt Skogseid, Barbro Eriksson, Eva T. Janson
Journal:
Neuroendocrinology
Neuroendocrinology (2009) 89 (3): 302–307.
Published Online: 29 January 2009
... Hospital for evaluation and follow-up between 1985 and 2004. Patients were monitored 1–3 times per year using plasma-chromogranin A (P-CgA), urinary 5-hydroxyindoleacetic acid (U-5HIAA) concentrations as well as radiological examinations, including ultrasonography, computerized tomography or magnetic...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (2009) 89 (3): 296–301.
Published Online: 07 October 2008
...Catharina M. Korse; Johannes M.G. Bonfrer; Neil K. Aaronson; Augustinus A.M. Hart; Babs G. Taal Background: Urinary 5-HIAA excretion is a well-known marker in neuroendocrine tumors (NETs), but it has a low sensitivity and the 24-hour collection is inconvenient for patients. Chromogranin A (CgA...
Journal Articles
Journal:
Neuroendocrinology
Neuroendocrinology (1989) 49 (1): 107–110.
Published Online: 02 April 2008
...Michel Grino; Thomas Wohlfarter; Reiner Fischer-CoIbrie; Lee E. Eiden The influence of the adrenal gland on the expression of chromogranin A in the anterior pituitary was studied in the rat. Adrenalectomy caused a progressive and pronounced (20% of control levels at day 10 after adrenalectomy...
Journal Articles
Stefan Mergler, Olaf Strauss, Mathias Strowski, Javier Prada, Adriana Drost, Jan Langrehr, Peter Neuhaus, Bertram Wiedenmann, Ursula Ploeckinger
Journal:
Neuroendocrinology
Neuroendocrinology (2006) 82 (2): 87–102.
Published Online: 22 February 2006
... are categorized into L-type channels (Ca V 1.1–1.4), P/Q-type channels (Ca V 2.1), N-type channels (Ca V 2.2), R-type channels (Ca V 2.3), and T-type channels (Ca V 3.1–3.3). Aside from regulating membrane excitability, VOCCs influence chromogranin A (CgA) secretion in neuroendocrine tumor (NET) cells...