... Mortality Cerebrospinal fluid Traumatic brain injury (TBI) is a heterogeneous condition in terms of clinical presentation, injury causation, and pathological mechanism after injury. Accurate stratification of the severity is crucial to guide treatment decisions, especially in severely injured...

... withdrawal on neuroactive steroid levels in plasma, cerebrospinal fluid and some brain regions as well as on the expression of classical and non-classical steroid receptors have been evaluated in male rats. After subchronic treatment (i.e., for 20 days) the following effects were detected: (i) depending...

... proteins, such as full-length APP (FL-APP) and its C-terminal fragment (APP-CTF). Levels of the neurosteroidogenic enzyme, P450scc, were also measured in brain homogenates. Luteinizing hormone Alzheimer’s disease Aging Guinea pig Gonadectomy GDX Beta amyloid Cerebrospinal fluid Brain...

... was conducted to elucidate the relationship between GH pulses and neuropeptide levels in the cerebrospinal fluid (CSF) of the third ventricle in ovariectomized goats. Methods: CSF and plasma samples were collected every 15 min. Levels of plasma GH and profiles of GH-releasing hormone (GHRH), somatostatin (SRIH...

.... In the first study, significant mitogenic activity in the Nb 2 lymphoma cell bioassay was detected in cerebrospinal fluid (CSF) samples collected by push-pull perfusion from rats on days 12–21 of pregnancy, coincident with the establishment of placental function. In contrast, mitogenic activity was absent from...

... implicated in the pathophysiology of mood and cognitive disturbances, we examined the cerebrospinal fluid (CSF) concentrations of immunoreactive somatostatin (IR-SRIF) in patients with Cushing’s disease and major depression and the relationship of these levels to CSF immunoreactive corticotropin-releasing...

... of IC TRH-Gly conversion to TRH suggests that IC TRH-Gly must first be converted to TRH by alpha-amidating enzymes in the cerebrospinal fluid before it transits the blood-brain barrier. TRH-Gly cross-reactivity with the TRH receptor of GH 3 cells was 0.45% of that for TRH while the in vitro potency...

...Janet A. Amico; Janine E. Janosky; Judy L. Cameron The effect of administration of estradiol (E 2 ) alone or combined with progesterone upon the circadian rhythm of oxytocin concentrations in cerebrospinal fluid (CSF) was examined in adult ovariectomized rhesus monkeys bearing temporary...

...István Barna; C.G.J. (Fred) Sweep; Dick Veldhuis; Victor M. Wiegant; David De Wied The concentration of β-endorphin-immunoreactivity (βE-IR) in cerebrospinal fluid (CSF) and plasma of rats was determined following intracerebroventricular (ICV) treatment of conscious animals with substances known...

.... Glucocorticoid receptor Stress Feedback Behaviour Cerebrospinal fluid Neuroendocrinology 47: 109-115(1988) © 1988 S. Karger AG, Basel 0028-3835/88/0471-0109 S 2.75/0 Antiglucocorticoid RU 38486 Attenuates Retention of a Behaviour and Disinhibits the Hypothalamic-Pituitary Adrenal Axis at Different Brain...

... of these neuropeptides in both plasma and cerebrospinal fluid (CSF). Subjects underwent two lumbar puncture studies, one of which was performed 100 min after oral administration of 5 µg/kg clonidine. Plasma AVP and OT were measured at a single time point 10 min before lumbar puncture. Both plasma and CSF AVP were...

...Janet A. Amico; Steven C. Levin; Judy L. Cameron Oxctocin and vasopressin (AVP) were previously reported to have a diurnal rhythm in cerebrospinal fluid (CSF) collected from the cervical cistern of chaired, intact male rhesus monkeys. In the present study, we continuously sampled CSF from temporary...

...William J. DeVito Immunoreactive prolactin (ir-PRL) has been identified in the cerebrospinal fluid (CSF) and brain of the male and female rat. In this study we determined the concentration of ir-PRL in the CSF and hypothalamus under conditions known to increase or decrease serum PRL. Hypophysectomy...

... noradrenergic and vasopressinergic systems is tonic in nature by measuring the response of cerebrospinal fluid (CSF) norepinephrine (NE) and arginine vasopressin (AVP) to the α 2 antagonist yohimbine in 7 young normal male human subjects. We also evaluated the tonic nature of α 2 -inhibition of the sympathetic...

...Frederick R. Bell; Peter A. Doris; Alan Simmonds Angiotensin II (AII), arginine vasopressin (AVP) and prolactin (PRL) were measured by radioimmunoassay in plasma and cerebrospinal fluid (CSF) in concurrent daily samples from conscious unrestrained steers. Packed cell volume, [Na+] and osmolality...

..., hypothalamus and cerebrospinal fluid (CSF) were then collected and analyzed for ACTH immunoreactivity. Additionally, hypothalamic tissue extracts were analyzed for corticotropin-releasing hormone (CRH) immunoreactivity. Dexamethasone significantly lowered peripheral levels of ACTH as measured in pituitary...

...Joe Herbert; Eric B. Keverne; Usanee Yodyingyuad Serum and cerebrospinal fluid (CSF) cortisol were measured by radioimmunoassay in male talapoin monkeys living in social groups. The slopes of the regressions between cortisol in the two compartments were significantly less in dominant than either...

...Jukka Jolkkonen; Leena Tuomisto; Tjeerd B. van Wimersma Greidanus; Esa Läärä; Paavo J. Riekkinen In male and female rats of two different age groups, we measured the arginine-vasopressin (AVP) levels in cerebrospinal fluid (CSF) collected at different times of the day. Mean values of AVP...

...Keith M. Kendrick; Eric B. Keverne; Basil A. Baldwin; Dennis F. Sharman Acetylcholinesterase (AChE) activity, and concentrations of monoamines, monoamine metabolites and oxytocin (OT) were measured in the cerebrospinal fluid (CSF) of sheep during late pregnancy, labour, parturition, vaginocervical...

...Mariana Morris; Larry E. Sain; Susan J. Schumacher Intraventricular perfusion with a hypertonic sodium chloride solution elicits increases in cerebrospinal fluid vasopressin and blood pressure and a decrease in heart rate. The central peptide response was greatly reduced in the hypertensive rat...