... with thyroxine increased levels of TRH in the PP by 20%, whereas in methimazole-treated, hypothyroid rats the content decreased by 25% versus untreated, euthyroid controls. Food deprivation for 3 days increased levels by 35% and refeeding completely normalized TRH content again. Also 14–17 days after castration...

... from hypothalamic tissue of male rats, and whether these effects could be modulated by testosterone (T). Mediobasal hypothalamic (MBH) or median eminence (ME) fragments from either sham-operated or castrated male rats (7 days) were placed in superfusion chambers and superfused with M199 for a 30-min...

... steroids Castration [Mgoacn^) -endocrinology Somatostatin and Somatoliberin Neuroendocrinology 1996;63:181-187 Corinne Estupinaa Albin Pinter0' Jorge Belmarb Hélène Astier0 Sandor Arancibia3 Laboratory of Neuroendocrinological Neurobiology. URA 1197 CNRS, University o f Montpellier 2, France...

.... On the contrary, in males, estradiol treatment did not cause changes in the total synapse counts at either time. As a further control, the lack of an estrogen-induced gonadotropin surge in long-term castrate males was also confirmed. Our study confirmed that in males estradiol does not alter the net synaptology...

... hormone receptor Gene expression Gonadal steroids Adrenal steroids Adrenalectomy Castration en[Mdmocr®inology Karen S.L. L am a Man Fong Leea Sau Ping Tama Gopesh Srivastavab Departments of Medicine and Pathology, University of Hong Kong Growth Hormone Regulation Neuroendocrinology 1996;63:475-480...

...Andrew N. Clancy; Richard P. Michael The H222 and ER-715 anti-estrogen receptor (ER) antibodies were used to examine the distribution of ER immunoreactive (ERir) neurons in hypothalamic and limbic sites of: (i) castrated male rats; (ii) castrated males implanted s.c. with silastic capsules...

...-microscopic level by means of the immunogold procedure. The immunoreactivity was always localized over the secretory granules. By using two sizes of gold particles, it was shown that NT- and β-LH-IR were colocalized in part of the cell granules. Castration caused a progressive decrease of the NT-IR in the β...

... was used as a marker of increased activation of NMDA receptors involved in stimulation of GnRH secretion. Here, we report on data obtained in intact and castrated rats at different ages. The aim was to determine whether the absence of gonads would affect the developmental changes in activation of NMDA...

... in vitro. In this report, we examine whether this phenomenon is also present in the male rat. Only in castrated male rats treated with estrogen were we able to demonstrate an increase in amphetamine-stimulated dopamine release in response to a direct infusion of P. Intact and castrated male rats treated...

...Dean E. Dluzen; Victor D. Ramirez In the present article we report that in vivo LHRH output as measured at the anterior pituitary following castration significantly increased, due to larger and more frequent LHRH signals arriving to this gland. This contrasts with the decreased amplitude...

...Theodore J. Cicero; Lynn H. O’Connor; Roy D. Bell There is a great deal of conflicting data regarding the issue of whether androgens influence opiate receptors in the whole male rat brain. Although Hahn and Fishman initially reported that long-term castration produced a large increase...

...Richard M. Kream; Andrew N. Clancy; M.S.A. Kumar; Thomas A. Schoenfeld; Foteos Macrides The effects of castration and testosterone (T) replacement on levels of substance P (SP) and luteinizing hormone-releasing hormone (LHRH) were assessed in discrete areas of the male hamster brain. The animals...

... significantly the acute increase of plasma LH produced by castration. Bicuculline prevented these effects. Delayed effects of GVG were observed when applied in the anterior hypothalamic area and ventromedial-arcuate nucleus area. In these latter areas, a single injection of GVG did not augment the GABA...

...Hemmie H.G. Berendsen; Alma J. Gower The effects of pretreatment with drugs on drug-induced yawning and penile erection in intact and chronically castrated rats were investigated. Naloxone partially blocked yawning in intact rats and in castrated rats pretreated with dihydro-testosterone propionate...

... Castration Incertohypothalamic dopaminergic neurons Original Papers Neuroendocrinology 269 275 ( 1986) Comparison of the Effects of Castration and Steroid Replacement on Incertohypothalamic Dopaminergic Neurons in Male and Female Rats Joseph W. Gunnel. K eith Lookinglanci. Kenneth E. Moore Department...

... section and thereafter immediately castrated or sham-castrated under cold anesthesia (males), injected with testosterone heptylate (1 mg s.c.) or olive oil used as solvent (females) before being put in the care of a nurse. The rise in plasma testosterone levels during the 1st h after birth was prevented...

..., castrated male rats received replacement levels of T (2 ng/ml) or chronic morphine (M) treatment for 7 days. When initiated at the time of castration, both T and M treatments prevented the castration-induced hypersecretion of LH. However, when the treatments commenced 2 weeks after castration, only T...

...Ayalla Barnea; Gloria Cho The effect of castration of male rats on the secretory function of median eminence area (MEA) granules containing luteinizing hormone-releasing hormone (LHRH) was examined, using copper as a test substance. LHRH granules, isolated from MEA of sham or castrated rats 1, 2...

... neurons were responsive to restraint following castration of the males. In addition, the ability of restraint stress to decrease TIDA neuronal activity was inhibited in castrated male rats by pretreatment with testosterone, and was facilitate in intact male rats by estradiol pretreatment. Neither...

... interaction. In this study, we addressed the question: do testicular steroids regulate the secretory response of LHRH neurons to copper? MEA, obtained from immature, mature, immature castrated and sham-operated rats, were incubated in the presence of various concentrations of copper for 15 min...