...: Lanreotide autogel (LAN) and temozolomide (TMZ) are guidelines-recommended monotherapies for thoracic neuroendocrine tumors (carcinoids; T-NETs), but prospective data for both combined and monotherapies are lacking. ATLANT (NCT02698410) evaluated efficacy and safety of LAN/TMZ in progressive T-NETs. Methods...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Stage IV Metastases Gastroenteropancreatic neuroendocrine tumors Lung Survival Brain Carcinoid Neuroendocrine neoplasms (NEN) constitute a heterogeneous group...

..., and anatomical location, and this is reflected by diverse biological behaviour and subsequent prognosis. Neuroendocrine tumour Carcinoid Endoscopy Surveillance © 2020 S. Karger AG, Basel 2020 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

... signature of disease progression. The integration of the quartet (epigenome, fibrosome, metastasome, NEDome) and the NETest score yielded a 93% accuracy in the prediction of future disease status. Biomarkers Carcinoid Ki-67 NETest Neuroendocrine neoplasia Neuroendocrine tumors Prognosis...

.... Histology revealed typical carcinoids (TC, n = 14), atypical carcinoids (AC, n = 14), small-cell lung cancer (SCLC, n = 11), and large-cell neuroendocrine carcinoma (LCNEC, n = 4). Disease status (stable or progressive) was evaluated according to RECIST v1.1. Blood sampling involved NETest ( n = 563...

...Anna Malczewska; Mark Kidd; Somer Matar; Beata Kos-Kudła; Lisa Bodei; Kjell Oberg; Irvin M. Modlin Background: Management of bronchopulmonary neuroendocrine neoplasia (NEN; pulmonary carcinoids [PCs], small-cell lung cancer [SCLC], and large cell neuroendocrine carcinoma) is hampered by the paucity...

...Ida Rapa; Arianna Votta; Jessica Giorcelli; Stefania Izzo; Angelica Rigutto; Jasna Metovic; Francesca Napoli; Marco Volante Aim: To validate the prognostic role of a panel of genes previously uncovered by our group to be specific targets of miRNAs differentially expressed in lung carcinoids...

... to in the content or advertisements. Appendiceal neuroendocrine neoplasms Right hemicolectomy Appendix Carcinoid Appendicectomy Neuroendocrine tumours Lymph node invasion Original Paper Neuroendocrinology 2019;109:179 186 DOI: 10.1159/000499381 Received: January 21, 2019 Accepted after revision...

.... Bronchopulmonary Lung Chromogranin A Biomarker Carcinoid Diagnosis Prognosis Cancer biomarkers are essential for the identification of disease and as tools to quantify disease progression (PD) and outcome. Numerous types of biomarkers have been proposed and studied [ 1 ]. Among these, dysregulated...

..., instructions or products referred to in the content or advertisements. Neuroendocrine tumor Metastases Chemotherapy Temozolomide Dacarbazine Pancreas Small-intestine Carcinoid Well-differentiated digestive neuroendocrine tumors (NET) are associated with distant metastases in 60–80...

...Ru Jia; Petra Sulentic; Jian-Ming Xu; Ashley B. Grossman Thymic neuroendocrine neoplasms are rare tumours, but their management can often be highly problematic. While previously assumed to be essentially variants of bronchopulmonary (lung) carcinoids, they are generally more aggressive and more...

... participants Neuroendocrine tumors of the small intestine are the most common causes of the carcinoid syndrome. Carcinoid heart disease occurs in more than half of the patients with the carcinoid syndrome. Patients with carcinoid heart disease who need to undergo surgery should also undergo preoperative...

...-Americans reported by Tsikitis et al. [ 17 ]. In the developed world, when studying the incidence by site, the distributions of primary tumours between Caucasian populations are similar, with a frequency of rectal carcinoids of less than 12%, while in African-Americans these NETs are the most common...

..., instructions or products referred to in the content or advertisements. Neuroendocrine tumor Carcinoid Bone metastases Epithelial-mesenchymal transition RANK CXCR4 EpCAM EpICD EpEX TGF-β1 Neuroendocrine tumors (NETs) are a heterogeneous group of malignancies characterized by a relatively...

..., instructions or products referred to in the content or advertisements. Bronchopulmonary neuroendocrine neoplasms Multiple endocrine neoplasia type 1 Carcinoid Neuroendocrine precursor lesion Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant inherited disorder caused...

... Jejunum Solid growth pattern Ki-67 index Prognosis Small intestine Neuroendocrine tumor Carcinoid Prognostication of small intestinal neuroendocrine tumors (SI-NET, previously known as jejunoileal carcinoids) is a notoriously difficult and controversial issue. Efforts to establish a useful...

...Simona Grozinsky-Glasberg; Ashley B. Grossman; David J. Gross Carcinoid heart disease (CHD) is a rare cardiac manifestation occurring in patients with advanced neuroendocrine tumours and the carcinoid syndrome, usually involving the right-sided heart valves and eventually leading to right heart...

...Ida Rapa; Arianna Votta; Barbara Felice; Luisella Righi; Jessica Giorcelli; Aldo Scarpa; Ernst-Jan M. Speel; Giorgio V. Scagliotti; Mauro Papotti; Marco Volante Aim: To extensively explore microRNA expression profiles in lung carcinoids in correlation with clinical and pathological features...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Small intestine Neuroendocrine tumor Carcinoid Staging Lymph node National Institutes of Health (NIH...

..., he did not respond radiographically. He proceeded to undergo a surgical thymectomy. Pathology demonstrated ‘moderately differentiated' carcinoid tumor with positive margins. He recurred several months later in the left supraclavicular region and underwent further cytoreductive surgery. Four years...