...Jianwei Zhang; Yanshuo Cao; Panpan Zhang; Xiaotian Zhang; Jian Li; Jun Zhou; Xicheng Wang; Zhi Peng; Yu Sun; Jie Li; Lin Shen; Ming Lu Objective: Gastroenteropancreatic neuroendocrine carcinoma (GEPNEC) is a major research focus, but the application of biomarkers to guide its prognostication...

... Pavel; Maxime Ronot Introduction: Tumor growth rate (TGR), percentage of change in tumor volume/month, has been previously identified as an early radiological biomarker for treatment monitoring in neuroendocrine tumor (NET) patients. We assessed the performance and reproducibility of TGR at 3 months...

... informed consent was obtained from all study participants. [email protected] 6 05 2020 2 07 2020 2 7 2020 Neuroendocrine tumors Carcinoid tumors NETest Biomarkers Tumor markers Neuroendocrine tumors (NETs) are a heterogenous group of neoplasms...

... to in the content or advertisements. Gastroenteropancreatic neuroendocrine tumors Biomarkers Liquid biopsy Survival Chromogranin A Overall survival and progression-free survival (PFS) rates diverge widely between the different subtypes of gastroenteropancreatic neuroendocrine tumors (GEP-NETs...

... signature of disease progression. The integration of the quartet (epigenome, fibrosome, metastasome, NEDome) and the NETest score yielded a 93% accuracy in the prediction of future disease status. Biomarkers Carcinoid Ki-67 NETest Neuroendocrine neoplasia Neuroendocrine tumors Prognosis...

..., with positive and negative predictive values of 32 and 85%. Conclusions: In this prospective study of gastroenteropancreatic NET patients, we observed only a weak association between a change in plasma CgA and changes in tumor burden. CgA as a single biomarker was thus inadequate to predict tumor progression...

...), the main unmet medical needs in the metastatic NENs setting were deeply discussed, and several proposals to try to solve them are presented in this article, including biomarkers, imaging, and therapy. [email protected] 2 07 2018 27 08 2018 28 8 2018 ©2018 S. Karger AG, Basel...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Biomarkers Cohort study Multivariate analysis Overall survival Pancreatic neuroendocrine tumours Prognostic factors Pancreatic neuroendocrine tumours (pNETs) are rare...

...Kjell Oberg; Anne Couvelard; Gianfranco Delle Fave; David Gross; Ashley Grossman; Robert T. Jensen; Ulrich-Frank Pape; Aurel Perren; Guido Rindi; Philippe Ruszniewski; Jean-Yves Scoazec; Staffan Welin; Bertram Wiedenmann; Diego Ferone; all other Antibes Consensus Conference participants Biomarkers...

... an unpredictable individual disease course and the tumors are often therapy resistant. Chromogranin A and 5-hydroxyindoleacetic acid are the biomarkers clinically used most often today, but there is a great need for novel diagnostic and prognostic biomarkers and new therapeutic targets. Sixty-nine biomarkers were...

... and outcome of NET has generally been modest. In order to achieve improved outcome in NET, a better understanding of NET biology combined with more reliable serum markers and better techniques to identify tumor localization and small lesions are needed. Although some NET biomarkers exist, sensitive...