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Keywords: Bax/Bcl-2
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Journal Articles
Nataly de Dios, Santiago Orrillo, Martín Irizarri, María Susana Theas, Florence Boutillon, Marianela Candolfi, Adriana Seilicovich, Vincent Goffin, Daniel Pisera, Jimena Ferraris
Journal:
Neuroendocrinology
Neuroendocrinology (2019) 108 (2): 84–97.
Published Online: 07 March 2019
... in GH3 cells and contributes to PRL-induced apoptosis by increasing the Bax/Bcl-2 ratio, (ii) PRL inhibits ERK1/2 and Akt phosphorylation, thereby contributing to its proapoptotic effect, and (iii) the PI3K/Akt pathway participates in the PRL-mediated control of lactotrope proliferation. We hypothesize...
Journal Articles
Verónica Zaldivar, María Laura Magri, Sandra Zárate, Gabriela Jaita, Guadalupe Eijo, Daniela Radl, Jimena Ferraris, Daniel Pisera, Adriana Seilicovich
Journal:
Neuroendocrinology
Neuroendocrinology (2009) 90 (3): 292–300.
Published Online: 14 August 2009
..., the expression of Bax was higher in anterior pituitary glands from rats at proestrus than at diestrus I, Bcl-2 protein levels showed no difference and Bcl-xL expression was lower, thus increasing the Bax/Bcl-2 ratio at proestrus. Assessed by annexin V binding and flow cytometry, the percentage of apoptotic...