... was demonstrated by mutating the sites from Lys-Lys to Lys-Arg. With such mutants, Rin m5F cells fully processed at both locations. Interestingly, the mutant Lys-Arg sites were not fully processed by AtT-20 cells. These results are discussed in terms of the complement of processing enzymes expressed in each...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Somatostatin receptors AtT-20 cells...

... in both AtT-20 cells and in mouse pituitaries. AtT-20 cells were treated with each of 6 steroids [aldosterone, corticosterone (Cort), Dex, β-estradiol (E 2 ), progesterone and testosterone] for 2 h. Dexras1 expression was assessed using both reverse transcription polymerase chain reaction (RT-PCR...

... mouse AtT-20 (fig.  3 ) and rat brainstem (not shown) RNA. Sequencing of this fragment unequivocally proved splicing of NESP onto exons 2, 3 and N1 (see fig.  1 b) yielding the prominent 1,800-bp mRNA. Posttranslational processing Molecular neuroendocrinology AtT-20 cells GNAS locus G-proteins...

...Jiangang Xie; Gregg T. Nagle; Gwen V. Childs; Aileen K. Ritchie Activation of adenylyl cyclase by corticotropin-releasing hormone (CRH) stimulates secretion of adrenocorticotropin (ACTH) in rat anterior pituitary corticotropes and in the murine AtT-20 cell line. The stimulation of secretion...