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Keywords: Apoptosis
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Journal Articles
Neuroendocrinology (2022) 112 (8): 744–762.
Published Online: 04 October 2021
..., instructions or products referred to in the content or advertisements. 2021 Graphic Abstract Streptozotocin Alzheimer’s disease Intestine Brain-gut axis Intestinal barrier Glucose-dependent insulinotropic polypeptide Incretin Oxidative stress Apoptosis Alzheimer’s disease (AD...
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Neuroendocrinology (2019) 108 (2): 84–97.
Published Online: 07 March 2019
... in GH3 cells and contributes to PRL-induced apoptosis by increasing the Bax/Bcl-2 ratio, (ii) PRL inhibits ERK1/2 and Akt phosphorylation, thereby contributing to its proapoptotic effect, and (iii) the PI3K/Akt pathway participates in the PRL-mediated control of lactotrope proliferation. We hypothesize...
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Neuroendocrinology (2016) 103 (5): 578–591.
Published Online: 28 October 2015
... with VPA and examined with respect to cell viability, cell cycle arrest, apoptosis, and global transcriptional response. Results: We found that VPA induced a dose-dependent growth inhibition of NET cells in vitro , which was mainly due to activation of extrinsic and intrinsic apoptotic pathways. VPA...
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Neuroendocrinology (2013) 98 (3): 171–179.
Published Online: 19 September 2013
...Jimena Ferraris; Sophie Bernichtein; Daniel Pisera; Vincent Goffin The anterior pituitary is permanently regulated by processes of apoptosis and proliferation in order to maintain tissue homeostasis. Several factors have been implicated in this regulation and lately, prolactin (PRL) has been...
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Neuroendocrinology (2004) 80 (2): 83–91.
Published Online: 09 June 2010
...Marianela Candolfi; Gabriela Jaita; Verónica Zaldivar; Sandra Zárate; Daniel Pisera; Adriana Seilicovich We previously reported that tumor necrosis factor-α (TNF-α) inhibits cell proliferation whereas it stimulates apoptosis of anterior pituitary cells in an estrogen-dependent manner. Also, we...
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Neuroendocrinology (2010) 91 (3): 256–267.
Published Online: 29 January 2010
... on proliferation or lead to tumour shrinkage are incompletely understood. To identify the mediators in the apoptotic cascades after DA or DA agonist challenges we used a well-characterized model system, the rodent somatolactotroph cell line GH3. In these cells, we show that apoptosis induced by the DA agonist...
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Neuroendocrinology (1993) 57 (1): 89–95.
Published Online: 08 April 2008
...Moreen Drewett; Joan Maty Jacobi; Lesley Ann Willgoss; Henry Martyn Lloyd Apoptosis was investigated by electron and light microscopy in the anterior pituitary gland of the male Fischer rat in which hyperplasia of prolactin-secreting cells had been induced by estrogen implanted subcutaneously for 6...
Journal Articles
Neuroendocrinology (2008) 88 (1): 43–52.
Published Online: 06 February 2008
... (6-OHDA), induce apoptosis in different cell types. DA receptors and DA transporter (DAT) were implicated in this action. Considering that estradiol sensitizes anterior pituitary cells to proapoptotic stimuli, we investigated the effect of estradiol on the apoptotic action of DA and 6-OHDA...
Journal Articles
Neuroendocrinology (2007) 84 (4): 217–221.
Published Online: 05 March 2007
..., has been reported by numerous investigators in this tumour type. More recently, a search for novel genes on the basis of their inappropriate methylation has led to identification of a novel pro-apoptotic gene. Its pituitary tumour derivation and role in drug-induced apoptosis resulted in the acronym...
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Journal Articles