... and in vitro in the rat. AVP was injected intravenously to Sprague-Dawley rats (1 µg/rat) through an indwelling jugular catheter. AVP stimulated ACTH release, with maximal effect 10 min after injection. Intravenous injection of three V 1b antagonists, [1-(β-mercapto-β, β-cyclopentamethylenepropionic acid),2-O...

...Rodolfo G. Goya; Maria G. Castro; Matthew J. Hannah; Yolanda E. Sosa; Philip J. Lowry Thymosin fraction five (TF5), a well-characterized immunoregulatory thymic preparation, has been reported to stimulate corticotropin (ACTH) release from rat pituitary cells. Since a previous study in our...

... into products which stimulate ACTH and β-endorphin release from the corticotrophs; the metabolizing enzyme (possibly a lipoxygenase or epoxygenase) is sensitive to NDGA and especially to ETYA. β-Endorphin release ACTH release Anterior pituitary Phospholipase A2 Cyclooxygenase Lipoxygenase Arachidonic...

... pituitary cells, AII (10 –8 M ) was found to potentiate the corticotropin-releasing activity of CRF producing a parallel shift of the dose-response curve. Similar results for ACTH release were observed in monolayer cell cultures. In this system, the concentration of cAMP was measured and was shown...

... acid metabolism may participate and have opposing regulatory effects: an inhibitory cyclooxygenase cascade and a stimulatory cascade possibly via the lipoxygenase. β-Endorphin release ACTH release Anterior pituitary Cyclooxygenase Lipoxygenase Arachidonic acid metabolites Nordihydroguaiaretic...

...Kazuharu Murakami; Kozo Hashimoto; Zensuke Ota Synthetic ovine corticotropin releasing factor (CRF) at 0.03–30 ng/ml evoked a significant linear release of ACTH in pituitary monolayer cell cultures. Arginine vasopressin (AVP) at 3–30 ng/ml induced a slight ACTH release in the same culture system...

...-Endorphin release ACTH release α-MSH release Brattleboro rats Neuroendocrinology 37:117-121 (1983) © 1983 S. Karger AG, Basel 0028-3835/83/0372-0117 $ 2.75/0 Vasopressin Is not Involved in the Catecholamine-Induced Release of ACTH, a-M SH and ß-Endorphin from the Rat Pituitary Gland Frank Berkenbosch...

..., instructions or products referred to in the content or advertisements. Corticotrophin-releasing factor (CRF) ACTH release Hypothalamic lesions CRF sensitivity of pituitary Neuroendocrinology 36:330-334 (1983) © 1983 S. Karger AG, Basel 0028-3835/83/0365-0330 $ 2.75/0 Responsiveness...

... corticosterone did not inhibit the plasma ACTH concentration, but 504 μg corticosterone significantly suppressed plasma ACTH levels. Infusion of 20 μg dexamethasone suppressed markedly the plasma ACTH concentration. These data suggest that the degree of inhibition of dexamethasone on ACTH release is about 25...

...E. Stark; G.B. Makara; J. Marton; M. Palkovits ACTH release in stress, measured by changesin the plasma corticosterone level, was studied in rats 24 h after isolation of the pituitary by surgical ablation of the medial hypothalamus. Injection of E. coli endotoxin or a large dose of formaldehyde...

... 2008 ACTH biosynthesis ACTH release Dexamethasone binding CRF Neuroendocrinology 15: 365-375 (1974) Pituitary Nuclear Retention of Dexamethasone and ACTH Biosynthesis B. Koch, B. Bucher and C. M ialhe Institut de Physiologie, Université Louis Pasteur, Strasbourg, and ERA No. 178...

... deprivation Septal lesions Feedback systems ACTH release Sabra strain rats (Ss) Neuroendocrinology 16: 156-164(1974) Pituitary-Adrenal Function after Small and Large Lesions in the Lateral Septal Area in Food-Deprived Rats D. R. Usher1, I. Lieblich and R. A. Siegel Hadassah Hospital-Hebrew University...

...G.B. Makara; E. Stark Sodium glutamate infused into the 3rd ventricle is a potent stimulus of ACTH release, as shown by the rise in plasma corticosterone levels. Glutamate failed to consistently increase the plasma corticosterone level in rats with deafferentation of the medial basal hypothalamus...