... of immunoreactive RFRP-3 in the neurons of the dorsomedial nucleus of the hypothalamus was monitored in sexually immature and mature laboratory mice (study I). In study II, the effects of serotonin and dopamine precursors (5-hydroxytryptophan and L -dihydroxyphenylalanine; injected daily, 8 or 12 h apart, for 13...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Serotonin Serotonin receptors 5-Hydroxytryptophan Prolactin...

... secretion via combined activation of 5-HT 1 , 5-HT 2 and 5-HT 3 receptors. Serotonin 5-HT 1 receptor 5-HT 2 receptor 5-HT 3 receptor 5-Hydroxytryptophan Prolactin Pituitary Neuroendocrine regulation 16 04 1991 31 07 1991 7 4 2008 © 1992 S. Karger AG, Basel 1992...

...Ching-Chow Chen The relationship between central catecholaminergic and serotonergic neurons and the development of streptozotocin-induced diabetic mice was examined over periods of 3, 14, 50 and 100 days. The accumulation of 3,4-dihydroxy-phenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) were...

... of melatonin, is low. Since tryptophan administration increases the concentration of pineal 5-HT at night, we examined its effect of melatonin production. Nighttime tryptophan loading led to substantial increases in pineal 5-hydroxytryptophan, 5-hydroxyindole acetic acid (5-HIAA), and 5-HT but a highly...

... of 40 pg 5-HIAA/min, which increased toward the dark phase to mean peak values of 195 pg 5-HIAA/min. Caudal cannulae placements revealed a low amplitude, high frequency, basal type of 5-HIAA release which did not increase toward the dark period (approximately 5 pg/min). 5-Hydroxytryptophan infusion...

.... It has been assumed, based on indirect evidence, that aromatic L-amino acid decarboxylase (L-AAD), the enzyme responsible for the conversion of L-5-hydroxytryptophan (5-HTP) to 5-HT as well as L-3,4-dihydroxyphenylalanine (L-dopa) to dopamine (DA), is ubiquitously distributed in most tissues of the body...

... following its drop was more dramatic as compared to the summer season. The intraperitoneal (i.p.) 5-hydroxytryptophan (5-HTP) administration blocked the compensatory increase in plasma T that followed its drop induced by hemicastration. At the same time, under similar experimental conditions, a preliminary...

... haloperidol, or by serotonergic receptor activation produced by fluoxetine, a serotonergic reuptake inhibitor plus 5-hydroxytryptophan, a serotonin precursor. Inhibition of prolactin release by benzodiazepine was dose related, and inhibition was still evident after repeated diazepam injection. The potency...

... and is again markedly elevated 96 h after adrenalectomy. We have examined serotonin (5HT) synthesis rates in several brain regions, anterior hypothalamus, posterior hypothalamus, and brain stem, at these times after adrenalectomy using the accumulation of 5-hydroxytryptophan (5HTP) after inhibition of aromatic...

...D. Cocchi; I. Gil-Ad; E. Panerai; V. Locatelli; E. Müller In 10 day-old female and male rats, administration of 5-hydroxytryptophan (5-HTP) induced a prompt elevation in plasma prolactin (Prl) and growth hormone (GH) levels. Pretreatment with 2 serotonin (5-HT) receptor blockers, methysergide (Meth...

.... 5-Hydroxytryptoρhan-decarboxylase activity 5-Hydroxytryptamine 5-Hydroxytryptophan Pineal gland Age Light © 1970 S. Karger AG, Basel 1970 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

..., the effect of an increase in endogenous brain serotonin on the response to an intragastric hypo- or hyperosmotic loading was studied in Wistar and AVP-deficient Brattleboro rats. 5-Hydroxytryptophan (5-HTP), the rate-limiting serotonin biosynthesis precursor known to increase the brain level of serotonin...

... in the hippocampus, hypothalamus and brain stem. We observed no change in the affinities of GR and MR sites in all the structures studied. In PCPA-treated rats, restoration of control 5-HT levels by injection of its immediate precursor, 5-hydroxytryptophan (5-HTP) brings the number of hippocampal MR-binding sites...