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Keywords: Tight junction barrier
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Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2015) 130 (2): 92–98.
Published Online: 09 May 2015
.... Postmortem studies previously discovered gut wall inflammation throughout the digestive tract in chronic dialysis patients. In CKD animals, colon wall inflammation is associated with breakdown of the epithelial tight junction barrier (‘leaky gut') and translocation of bacterial DNA and endotoxin...