... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Cystinuria Nephrolithiasis Immunology Proximal tubule Atopia Inflammation Cystinuria (CYS) is a rare genetic disorder involving the transport of dibasic...

...Yuji Oe; Volker Vallon Background: In acute kidney injury (AKI), proximal tubules are a primary site of injury, resulting in significant alterations in amino acid transport and metabolism. However, little is known about the therapeutic potential of targeting amino acid transporters. Here, we...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Acute kidney injury Metabolism Proximal tubule Transcription factors NIH The Krüppel-like factor (KLF) transcription factors are a family...

...Sandra Hummelgaard; Kathrin Weyer The kidney proximal tubule is a major target tissue of the renin-angiotensin system (RAS). Megalin is an endocytic multiligand receptor abundantly expressed in the proximal tubule where it drives reabsorption of peptides and proteins from the glomerular...

...Sian E. Piret; Sandeep K. Mallipattu The proximal tubule (PT) is a major target in acute kidney injury (AKI), leading to profound changes in PT cell biology. Amongst the genes with early and robust changes in expression are many transcription factors (TFs), which themselves account for other...

... proteinuric obese subjects compared with controls. However, a protein meal led to a delayed glomerular hyperfiltration in obese patients compared with controls. Conclusion: This study shows that obese patients, in the absence of significant comorbidities, have a normal proximal tubule Na + absorption at basal...

... results in improved kidney regeneration and decreased capillary rarefaction after ischemia-reperfusion injury. Am J Physiol Renal Physiol 2012;302:F183-F191. Telomerase T Telomerase C Renal ischemia reperfusion  Autophagy Proximal tubule Mammalian target of rapamycin Senescence p16...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Glucose Proximal tubule SGLT2 The relationship between plasma glucose and renal glucose filtration, reabsorption and excretion is described as a threshold type...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Contrast media Dehydration Kidney Proximal tubule Lysosome Light microscopy...

... segments. Southern blot hybridization of PCR products obtained from nephron segments with the CYP4A1 cDNA probe demonstrated strong signals in S2 and S3 segments of the proximal tubule. Immunoblots of nephron segments using a polyclonal anti-rat liver CYP4A1 antibody which cross-reacts with CYP4A2...

... rate, GFR), also appeared to be reduced (11.3 ± 1.6 versus 13.8 + 2.5%, p < 0.05), suggesting compensatory increased proximal reabsorption. In disagreement with the latter, C Li /GFR, alleged to be a measure of fractional sodium and water output from the proximal tubules, was increased (36.2 ± 1.8...

... on the proximal tubule, thick ascending limb and/or inner medullary collecting duct (IMCD). In vitro measurements of 3 H 2 O permeability of perfused IMCD of normal rats showed that vasopressin (50 μU/ ml) added to the bath increased the diffusional water permeability (43.4 ± 4.8 vs. 105.6 ± 9.1×10 -5 cm/s...

..., microvesicles and cytosomes. Evidence suggestive of the fusion between AcPase-positive bodies and large apical vacuoles was seen, and release of AcPase into the lumen and basal membrane of PT cells sometimes encountered. The possible significance of this phenomenon is discussed. Proximal tubule...

...S.I. Ryabov; V.Y. Plotkin; I.J. Freici; A.J. Nevorotin The amount of forming pinocytic (coated) microvesicles on the apical plasma membrane of kidney proximal tubule cells was assessed in kidney biopsies of 10 patients suffering from chronic glomerulonephritis. A significant correlation was found...

... and The University of Pittsburgh School of Medicine, Pittsburgh, Pa., and The University of Pennsylvania Medical Service, Philadelphia Veterans Administration Hospital, Philadelphia, Pa. Key Words. Serum phosphate Bicarbonate reabsorption Bicarbonate transport Phos­ phate transport Proximal tubule...

... & Co. Ltd., Basle Key Words. Microperfusion Peritubular capillaries Proximal tubule Sodium and water reabsorption Acetazolamide Abstract. The microperfusion pump described in this paper allows to perfuse the same peri­ tubular capillary area on the renal surface with different test solutions...

...Klaus O. Stumpe; B. Reinelt; C. Ressel; H. Klein; F. Krück Sodium excretion and proximal tubule function were studied in rats with an aorta-to-vena cava (A-V) fistula using the techniques of micropuncture. 15–28 days after ereation of the fistula, 40% of the rats had developed peripheral edema...

...G. Spear The belief that the swan-neck lesion or the Fanconi syndrome in cystinosis are related to the accumulation of cystine in epithelium of the proximal tubule is questioned. The vulnerability of the visceral glomerular epithelium in cystinosis is emphasized. 27 11 2008 © 1973 S...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Na + /H + exchanger Hypertension Kidney Fusion protein Prostaglandin E 2 Thromboxane B 2 Proximal tubule...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Advanced glycation end product Disposal, pentosidine JTC-12-cell Proximal tubule Pentosidine, an advanced glycation end product (AGE...