...A. Davenport; E.J. Will; A.M. Davison Although prostacyclin has been reported to be an effective extracorporeal anticoagulant for intermittent haemofíltration and dialysis treatments, it has been suggested that it is inferior to heparin in preventing clotting in spontaneously driven continuous...

...P. Rigotti; P. Amodio; D. Sacerdoti; M. Ferraresso; M. Borsato; E. Morpurgo; F. Menon; P. Angeli Defibrotide (DF) has been proposed as a new antithrombotic agent in renal transplantation. Because it was also found to increase prostacyclin synthesis, a reduction in ciclosporin (CS) nephrotoxicity...

...A. Davenport; E.J. Will; A.M. Davison Prior to commencing renal replacement therapy, 8 patients with fulminant hepatic failure and acute renal failure were treated with an infusion of prostacyclin, 5 ng/kg/min, for 30 min, administered directly into the femoral vein. During this period, several...

..., instructions or products referred to in the content or advertisements. Platelets Coagulation Hemodialysis Prostacyclin 15 03 1991 11 12 2008 Nephron 1991;59:567-572 ©1991 S. Karger AG, Basel 0028-2766/91/0594-0567S2.75/0 Evaluation of Platelets and Hemostasis during Hemodialysis...

... dialysis in the presence of both heparin and prostacyclin. During each dialysis session the platelet system was examined three times: prior to, after 90 min, and at the end of the procedure. As compared with the situation prior to dialysis, the number of platelet aggregates assessed after 90 min...

... to in the content or advertisements. Thrombin Glomeruli Macrophage Prostacyclin Thromboxane B 2 Glomerulonephritis Nephron 1989;53:50-53 © 1989 S. Karger AG. Basel 0028 2766/89/0531 0050S2.75/0 Thrombin Inhibits the Synthesis of Prostanoids by Isolated Glomeruli and Peritoneal Macrophages in Rats1 E...

...Bernard Canaud; Charles Mion; Augusto Arujo; Quy Vu. N’Guyen; Georges Paleyrac; Sylvie Hemmendinger; Jean Pierre Cazenave Prostacyclin (PGl 2 ), the most potent and short-lived antiplatelet agent known today, has been used successfully as an antithrombotic in hemodialysis (HD). However, its...

... to these toxins. Prostacyclin (PGI 2 ) is a potent renal vasodilator and inhibitor of platelet aggregation and adhesion. An inability to produce PGI 2 in response to endothelial cell injury could drive the pathogenic cascade. We therefore used a baboon model of HUS to measure PGI 2 production following...