... intravenous heparin during hemodialysis. She developed severe necrotic cutaneous ulcers over both legs, with typical histological findings. Thrombocytopenia never occurred but platelet studies demonstrated enhanced aggregation when heparin was added in vitro. Platelet-aggregating immunoglobulins produced...

... coagulation Glomerular sclerosis Platelet aggregation IgA nephropathy Cross-linked fibrin 28 09 1990 11 12 2008 © 1991 S. Karger AG, Basel 1991 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages...

...) significantly shortened at stage II and prolonged again at stage III. Although there were no significant changes in platelet aggregation, plasma TxB 2 , 6-keto-PGF 1α , F.VIII :C and F.VIII :Ag levels throughout the study, platelet adhesion and von Willebrand factor (vWf):Ag significantly increased at stages II...

...Marek Kuźniewski; Władysław Sułowicz; Zygmunt Hanicki; Jan Kus; Maria Nowogrodzka-Zagórska; Elźbieta Kostka-Trabka; Krzysztof Bieroń; Aldona Dębińska-Kieć The number of circulating platelet aggregates determined according to the method of Wu and Hoak and the platelet morphology revealed by scanning...

... significantly lower in the OKY-046-treated diabetic rats than in the untreated diabetics (60.8 ± 23.2 vs. 94.1 ± 33.4 mg/day in the 16th week, p < 0.05 and 424.4 ± 93.3 vs. 614.4 ± 102.3 mg/dl in the 16th week, p < 0.01, respectively). Platelet aggregation was inhibited by OKY-046. Blood urea nitrogen...

... after the fish oil treatment. Red blood cell filterability significantly increased in the treated group compared with the case of the control group. Epinephrine-induced platelet aggregation increased significantly in the control group, and this change was significantly different from that of the treated...

... a rise in platelet aggregation and serum triglyceride concentration in hemodialyzed patients. The present double-blind cross-over study has been performed to evaluate the influence of L -carnitine when compared with placebo on platelet aggregation and plasma concentrations of various factors involved...

... of the arachidonate pathway and subsequent thromboxane production. Since the etiopathogeny of this platelet abnormality seems to be related to abnormalities in lipid metabolism, compounds such as fish oil must be beneficial in the management of this risk factor. Platelet aggregation Continuous ambulatory...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Dense bodies Uremia Adenosine diphosphate Platelet aggregation Nephron 1988;50:306-307 C 1988 S. Karger AG. Basel 0028-27688 0504 0306S2.75 0 Mepacrine-Labeled Platelet Dense-Body Number...

...A. Viener; M. Aviram; O.S. Better; J.G Brook Hemodialysis patients suffer from premature atherosclerosis and various thrombotic and thromboembolic phenomena. Despite enhanced in vivo platelet activity, it is unclear whether in vitro platelet aggregation is increased or reduced in this population...

...% fall in triglycerides, a 10% rise of high-density lipoprotein (HDL) cholesterol, a 36% rise of HDL 2 cholesterol fraction and a 54% rise of the HDL 2 :HDL 3 cholesterol ratio. The platelet aggregation to adenosine diphosphate and collagen was significantly reduced. The activated whole-blood clotting...

... phosphatase) and radiographic examinations (x-ray films of the hand skeleton). This study showed impaired platelet aggregation in group I patients, compared to either group II patients or controls. There were no significant differences when group II patients were compared to controls. No significant...

...J. Charvát; J. König; J. Bláha The platelet aggregation – enhancing action of heparin with adenosine diphosphate and epinephrine was tested in vitro in a group of volunteers. This action of heparin can be eliminated by protamine sulphate which has no effect on platelet aggregation. In dialyzed...

... in the treatment of primary systemic carnitine deficiency. 10 uremic patients on hemodialysis were randomly selected into a control group (4 patients) treated by placebo and a treatment group (6 patients) treated by L -carnitine. Plasma lipoprotein concentration and composition as well as platelet aggregation were...

...Hisao Mabuchi; Hisamitsu Nakahashi Platelet aggregation inhibitors were isolated from the blood of dialyzed patients by high-performance liquid chromatography. At least two inhibitors exist in the blood of dialyzed patients. These inhibitors not only inhibit platelet aggregation, but also suppress...

... increased almost 3-fold. Coagulation and fibrinolytic studies suggested a hypercoagulable state and increased fibrinolytic activity. Platelet aggregation showed the reduction of maximum aggregation induced by ADP and collagen. Histological examination by light microscopy, immunofiuorescence, and electron...

... periodically flushed with physiologic saline. No significant clotting of the hemodialyzers was encountered in uneventful dialyses. Platelet counts, platelet aggregation with ADP and epinephrine, antithrombin III and fibrinogen/fibrin degradation products were not significantly changed compared with pre...

...G.G. Nenci; M. Berrettini; G. Agnelli; P. Parise; U. Buoncristiani; E. Ballatori Quantitation of the thrombocytopathy of uraemics may be one useful way of evaluating forms of therapy. 24 patients treated by haemodialysis and peritoneal dialysis at two different times had platelet aggregation...

... in uremic patients. Treatment with recombinant human erythropoietin (rHuEPO) may shift the precarious hemostatic balance towards thrombosis. Therefore, the aim of the study was to assess the relationships between leptin and platelet aggregation and some hemostatic parameters in CAPD patients treated...

..., parathormone, total cholesterol, triglycerides, viral hepatitis B/C markers, liver enzyme, and aluminium were determined. Platelet aggregations in response to ristocetin (RIPA), adenosine diphosphate, and collagen were measured in whole blood (electric impedance method) and platelet-rich plasma (optical...