...) showed an abnormal reponse to ouabain associated with an inhibition of cardiac Na + /K + /ATPase activity and with a decrease in the high affinity 3 H-ouabain binding sites. The extent to which both actions were improved with the recombinant human erythropoietin (rHuEpo) treatment suggests that the lack...

.... Ouabain-sensitive phosphate release, however, was decreased. For RBCs of controls and uremic subjects approximately 80% of inorganic phosphate liberated within the cell was recycled. Thus, RBC phosphate release represents 20% of intracellular phosphate ester metabolism. In uremia active electrolyte...

..., that renin secretion increases with increasing medium sodium concentration. However, in the presence of 10 -3 m ouabain, renin secretion decreased with increasing medium sodium concentration. We also found that intracellular sodium concentration varied directly with medium sodium both in the presence...