... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Acute renal infarction Risk factors Obesity Acute renal infarction (ARI) is caused due to the interruption of blood supply to the kidneys [ 1 ]. It is a rare...

... is currently the gold standard to obtain cortical specimens. However, in cases where ultrasound-guided kidney biopsy is not deemed safe (obese patients, deep kidneys, or kidneys with a complicated anatomy), CT-guided kidney biopsy could be a convenient alternative to obtain renal tissue samples. The aim...

... or occult diabetes. At 12 months, 53 patients had normal glucose metabolism, 25 prediabetes, and 32 PTDM. In multiple regression analysis, pre-transplant inflammation was not a risk factor for prediabetes or PTDM. This was attributed to the high interrelation between obesity, prediabetes, and inflammation...

...Radovan Hojs; Robert Ekart; Sebastjan Bevc; Nina Vodošek Hojs There is a pandemic of obesity worldwide and in Europe up to 30% of the adult population is already obese. Obesity is strongly related to the risk of CKD, progression of CKD, and end-stage renal disease (ESRD), also after adjustment...

... recent advances in understanding the roles of sPPR in animal models of hypertension. Fig. 2. Schematic illustration of the proposed role of sPRR in obesity hypertension. Circulating sPRR is elevated in obese animals and may contribute to elevated BP through multiple mechanisms involving renal Na...

...Justo Sandino; Lucia Cordero Garcia-Galán; Lucia Aubert Girbal; Manuel Praga; Julio Pascual; Enrique Morales Treatment for obesity in patients with CKD englobes a wide range of options, from lifestyle modification to bariatric surgery. Weight loss improves metabolic parameters and stimulates...

...Akiko Toda; Shigeko Hara; Hiroshi Tsuji; Yasuji Arase Introduction: Obesity is a risk factor for chronic kidney disease (CKD), but whether the reduction of body mass index (BMI) helps prevent CKD is controversial. Recently, obese metabolic phenotypes have raised considerable interest. We thus...

...Maria Quero; Nuria Montero; Inés Rama; Sergi Codina; Carlos Couceiro; Josep M. Cruzado Background: Data from the WHO show an increasing rate of overweight and obesity in general population in the last decades. This increase in obesity also affects population with end-stage renal disease (ESRD...

...Marina Martin-Taboada; Rocío Vila-Bedmar; Gema Medina-Gómez Obesity is directly associated with an increased risk of developing CKD, regardless of other comorbid conditions. Although the molecular mechanisms that link both diseases are not well established, the role of adipose tissue...

..., inevitably fail. In obesity, this syndrome is exacerbated due to the complications of adipose tissue dysfunction, in the so-called cardiorenal metabolic syndrome (CRMetS). Obesity promotes adipose tissue dysfunction because it exceeds lipid storage capacity and leads to a lipotoxic state, characterized...

...Justo Sandino; Leonella Luzardo; Enrique Morales; Manuel Praga Obesity-related glomerulopathy (ORG) is an increasingly recognized cause of end-stage kidney disease. The most common clinical presentation is a slowly increasing nonnephrotic proteinuria that is followed by a progressive decline...

... Background/Aims: Obesity is a known risk factor for cardiovascular disease and contributes to the development and progression of kidney disease. However, the specific influence of obesity on outcomes in primary glomerular disease has not been well characterized. Methods: In this prospective cohort study...

...William P. Martin; Carel W. le Roux; Neil G. Docherty Background: Surgical approaches to the treatment of obesity and type 2 diabetes, most notably the Roux-en-Y gastric bypass (RYGB) procedure, have been shown to be renoprotective, reducing the incidence of albuminuria and end-stage kidney disease...

...Avry Chagnac; Boris Zingerman; Benaya Rozen-Zvi; Michal Herman-Edelstein Background: Glomerular hyperfiltration (GH) is a hallmark of renal dysfunction in diabetes and obesity. Recent clinical trials demonstrated that SGLT2 inhibitors are renoprotective, possibly by abating hyperfiltration...

...Elia Escasany; Adriana Izquierdo-Lahuerta; Gema Medina-Gomez The recent and ongoing worldwide increase in the prevalence of obesity parallels the increase in the incidence of chronic kidney disease (CKD). This association suggests an implication of lipotoxicity in the development of kidney diseases...

...Liane Correia-Costa; Ana Azevedo; Alberto Caldas Afonso Obesity is known to be associated with a myriad of cardiovascular and metabolic comorbidities. In children, several longitudinal studies have shown that obesity consequences start early in life and accompany the obese child into adulthood...

...Pietro Anastasio; Davide Viggiano; Miriam Zacchia; Claudia Altobelli; Giovambattista Capasso; Natale Gaspare De Santo Background/Aims: Little information is available about the tubular functions and the renal adjustments that take place in obese subjects after a protein meal. How the excess fat may...

...Csaba P. Kovesdy; Susan L. Furth; Carmine Zoccali; on behalf of the World Kidney Day Steering Committee Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes...

..., no population-based study has focused on the impact of PPARG gene-abdominal obesity interaction on DN risk. The aim of this study was to investigate the impact of PPARG polymorphisms and its interaction with abdominal obesity on DN risk in the Chinese Han population. Methods: A total of 848 patients with type 2...

...Donald E. Wesson; Neil A. Kurtzman; Pedro Frommer The association between massive obesity and nephrotic syndrome has been rarely reported. We herein describe a patient with massive obesity (209 kg) and nephrotic proteinuria who had a normal renal biopsy. The patient was initially polycythemic...