...Efstathios Mitsopoulos; Panagiotis Pateinakis; Christodoulos Keskinis; Dorothea Papadopoulou The combination of nephrotic syndrome with mild histopathological lesions of IgA nephropathy is considered by some as a special form of IgA nephropathy with superimposed minimal change disease (MCD) while...

...%); sepsis (26.6%), severe malaria (15.4%), and nephrotic syndrome (14.8%) were common AKI causes. Fever (72.8%), pallor (52.1%), and vomiting (45.6%) were the most common symptoms. Thirty-two (27.8%) patients had high blood pressure. Inhospital mortality was 14.8% (95% CI: 9.8, 21.1). The cumulative...

...: Altogether, 19 patients with AA amyloidosis and HIV infection were found with 68% of men and median age at amyloidosis diagnosis of 38 years (range 28–75 years). Clinical presentation was nephrotic syndrome in 94% ( n = 17/18). Among patients with renal involvement and assessable outcome ( n = 17), 11 (64.7...

..., data were from 541 participants enrolled in the Nephrotic Syndrome Study Network (NEPTUNE), between 2010 and 2019, at 23 sites across North America. Blood pressure, lipids, and kidney disease outcomes including complete proteinuria remission, kidney failure, and chronic kidney disease progression were...

... HBV-GN). The aim of this prospective study was to evaluate the efficacy and safety of corticosteroids in the treatment of sn HBV-GN. Methods: Twenty-six patients with nephrotic syndrome induced by seronegative HBV-associated membranous nephropathy were enrolled. The patients were given...

...Chen Ling; Zhi Chen; Jianfeng Fan; Qiang Sun; Xiaolin Wang; Lin Hua; Jingang Gui; Xiaorong Liu Introduction: A significant proportion of children with SSNS (steroid-sensitive nephrotic syndrome) experience recurrence. Reliable biomarkers to predict flare are currently lacking because...

... to be greater than previously thought. aHUS and nephrotic syndromes associated with CMV infection are rare. Identification of triggers for aHUS manifestation in a genetically susceptible patient is extremely important since this permits a faster initiation of treatment and clinical improvement. We report a case...

..., it is expected that future scientific progress will enable a patient-centered medicine based on concept-driven therapies. Summary: MN is the most common cause of nephrotic syndrome (NS) in white adults. Approximately one-third of patients achieve spontaneous remission, one-third remain stable, and one-third have...

...Fatma Yazılıtaş; Fatma Zehra Oztek-Celebi; Özcan Erel; Evrim Kargın Çakıcı; Murat Alışık; Mehmet Bülbül Background: There is a growing body of evidence showing that there is an association between oxidative damage and kidney injury in patients with nephrotic syndrome (NS). Dynamic thiol/disulphide...

... to evaluate these biopsies after obtaining well-informed consent from each patient. Results: Of the 221 biopsies carried out, 150 were performed on males and 71 on females with the mean age of 29 ± 13.5 years. The main presentation was the nephrotic syndrome in 177 (80%), hypertension in 60 (27%), renal...

... of glomerular basement membrane (GBM). The association of AS and immunocomplex nephropathies is uncommon. This is a case of a 37-year-old woman with family history of X-linked AS, including 4 affected sons. This patient developed full-blown nephrotic syndrome along a 3-month period, a presentation...

...Paolo Cravedi Many prospective studies and a recent randomized controlled trial have shown that the B-cell-depleting monoclonal antibody, rituximab, safely promotes the remission of nephrotic syndrome in approximately 65% of patients with membranous nephropathy (MN). Mechanistic studies have...

...Alastair J. Rankin; Emily P. McQuarrie; Jonathan G. Fox; Colin C. Geddes; Bruce MacKinnon; on behalf of the Scottish Renal Biopsy Registry Background: The reported incidence of venous thromboembolism (VTE) in patients with nephrotic syndrome (NS) varies widely, as does the approach to prophylactic...

...Kezhen Tong; Jianhua Mao; Haidong Fu; Huijun Shen; Aimin Liu; Qiang Shu; Lizhong Du Background: Mycophenolate mofetil (MMF) is an alternative treatment strategy in children with steroid sensitivity who have frequent relapses or steroid-dependent nephrotic syndrome (FRNS/SDNS). Methods: From January...

... of nephrotic syndrome in children. Recently, several case reports have revealed that IgAN can be complicated by MCD in adults. Here, we report our experience concerning the features of such patients in pediatrics. Methods: The clinical manifestations and pathological features of 197 children who presented...

...Toshihiko Ishimitsu; Hidehiko Ono; Mutsumi Sugiyama; Hiroshi Asakawa; Kazuo Oka; Atsushi Numabe; Minoru Abe; Hiroaki Matsuoka; Shigeru Yagi A 62-year-old woman presented with nephrotic syndrome and severe anemia although the renal function was not impaired. Renal biopsy revealed the histology...

...-resistant and 39 steroid-sensitive children with nephrotic syndrome whose glomerular filtration rates were within the normal range. Fourteen healthy children were taken as controls. U-NAG and U-β 2 M levels did not show a difference between the steroid-resistant and steroid-sensitive groups but were...

...Donald E. Wesson; Neil A. Kurtzman; Pedro Frommer The association between massive obesity and nephrotic syndrome has been rarely reported. We herein describe a patient with massive obesity (209 kg) and nephrotic proteinuria who had a normal renal biopsy. The patient was initially polycythemic...

...Tomoyuki Kobayashi; Junzo Suzuki; Masakatu Watanabe; Sigeo Suzuki; Kazuo Yoshida; Kazunari Kume; Hitoshi Suzuki In order to examine the intracellular thromboxane A 2 (TXA 2 ) signal transduction system in platelets of patients with nephrotic syndrome, we measured the levels of TXA 2 metabolites...

..., instructions or products referred to in the content or advertisements. Phosphatidylinositol turnover PGE 2 receptor Sairei-to Chinese herbal medicine Nephrotic syndrome NEPHRON Original Paper Nephron 1997:75:208-212 Accepted: April 11 .1996 Junzo Suzuki Kenji Watanabe Tomoyuki Kobayashi Kazuo...