.... The primary outcome is a composite of dialysis dependence or all-cause mortality at day 90. Conclusion: The SCD is a cell-directed extracorporeal therapy that targets and deactivates pro-inflammatory neutrophils and monocytes, with evidence of efficacy across a variety of critically ill patient populations...

..., instructions or products referred to in the content or advertisements. Immune cell infiltration Neutrophils Monocytes Tubular injury Sterile inflammation Innate immunity National Institutes of Health (NIH) 10.13039/100000002 The kidneys maintain systemic water, salt, and pH...

...Annemieke W. Dhondt; Raymond C. Vanholder; Marie-Anne F. Waterloos; Griet L. Glorieux; Severin MG. Ringoir The expression of CD 14 on monocytes and CD45 on monocytes and granulocytes was evaluated during hemodialysis by flow cytometric analysis in the ‘resting state’ and after in vitro stimulation...

... The effect of recombinant human interleukin-10 (IL-10) on the in vitro cyto-kine secretion of peripheral blood monocytes (PBM) was evaluated in patients with IgA nephropathy (IgAN). Significantly increased spontaneous and lipopolysaccharide (LPS)-stimulated secretion of tumor necrosis factor-α...

...Koichi Matsumoto In this study we have examined the effects of recombinant human interleukin (IL)-13 on peripheral blood monocytes (PBM) from patients with IgA nephropathy (IgAN). Significantly increased spontaneous and lipopolysaccharide (LPS)-stimulated secretion of tumor necrosis factor-α (TNF...

... to in the content or advertisements. Tumor necrosis factor Hemodialysis Monocytes Mononuclear cells Cytokines Original Paper Nephron 1993;65:273-277 Christie Macdonald David N. Rush Keevin N. Bernstein Rachel M. McKenna Departments of Internal Medicine and Medical Microbiology, Health Sciences Centre...

...José A. Riancho; Maria T. Zarrabeitia; Angel L.M. de Francisco; José A. Amado; José Napal; Manuel Arias; Jesus Gonzalez-Macias In studies in vitro calcitriol (1,25-dihydroxyvitamin D 3 ) inhibits lymphocyte proliferation and modulates several monocyte functions, including the secretion...

... are able to induce the production of IL-6 by human monocytes. Anaphylatoxins can be generated following complement activation by cellulosic membrane dialysis. C5a is known to potentiate the LPS-induced production of IL-1 and TNFα, and we established that recombinant human C5a was able to act...

...Brigitte Schiller; H.W.L. Ziegler-Heitbwck; Nicolette Meyer; Bärbel Schmidt; Matthias Blumenstein The expression of MHC class II (HLA-DR) and complement receptor (CRl) surface molecules on CD 14 + monocytes were compared with the production of the monokine interleukin-1β (IL-1β) in patients...

... fraction, compared to responders (R) and C (p < 0.05), and higher monocyte (p < 0.00001) and WBC (p < 0.002) counts, with lower lymphocyte fraction (p < 0.001), compared to R. We suggest that NR could represent a selected group of ESRD patients, screenable by these easily detectable features...

...T. Glazer; P. Fishman; B. Klein; J. Levi; M. Djaldetti The phagocytic activity of monocytes from 15 uremic patients was estimated by the superoxide anion test. There was a significant decrease in the ability of monocytes from these patients to produce superoxide anions in comparison with monocytes...

...Silvano Lamperi; Silvia Carozzi The Tlymphocytes, OKT4-depleted T lymphocytes, monocytes, macrophages and the bone marrow early erythroid progenitor (BFU-E) interactions have been evaluated in normal subjects and in uremic patients in predialysis phase (PDP), on hemodialysis (HD) or continuous...

...Gianna Mazzucco; Guido Monga A focal discontinuity of glomerular basement membrane (GBM) with extravasation of a monocyte is described in a case of acute postinfectious glomerulonephritis in a 2-year-old girl. It is proposed that also monocytes could play a role in causing disruption of glomerular...

... and monocytes, but the number of granulocytes was significantly lower in the bladder and kidneys of the recently healed animals. Likewise, the plasma cells were fewer in healed animals than in infected ones, the difference being statistically significant for bladders and on the verge of significance for kidneys...

...W.E.M. Schouten; M.P.C. Grooteman; M. Schoorl; A.J. van Houte; M.J. Nubé Background/Aims: Monocyte activation and subsequent cytokine generation is presumed to be involved in haemodialysis (HD)-related morbidity. The present study was designed to investigate HD-induced changes in monocytes...

...Sophie Jégo; Siham Sabri; Mireille Soler; Catherine Farnarier; Aline Lucioni; Bertrand Dussol; Pierre Bongrand; Yvon Berland; Colette Foa In human cultured monocytic cells stimulated by cytokines, CD43 was demonstrated to exhibit a modification of sialylated epitopes (dys-sialylation) [Soler et al...