...Pei Zhang; Xiao Yang; Meng-zhen Fu; Chun-lin Gao; Xiang Fang; Zheng-kun Xia Background: Thrombotic microangiopathy (TMA) is an important risk factor for the prognosis of lupus nephritis (LN). Patients with LN complicated with TMA tend to be critically ill with high mortality and poor prognosis...

... was detected in patients’ sera. Here, we reported a case of NCAM1-positive lupus nephritis (class V+III) developed from MN. The patient was refractory to multiple immunosuppressive regimens but achieved remission after the application of rituximab as an add-on therapy and showed a reduction of anti-NCAM1...

...Hae Yoon Grace Choung; Catherine Moore; Thu H. Le; Paul Guirguis; Jack M. McKeown; Jerome Jean-Gilles; Bruce Goldman Introduction: The pathologic features of membranous lupus nephritis (MLN) are occasionally encountered in secondary membranous nephropathy (sMN) without overt clinical evidence...

...Ruihua Liu; Yuan Peng; Hongjian Ye; Xi Xia; Wei Chen; Fengxian Huang; Zhijian Li; Xiao Yang Introduction: The aim of this study was to evaluate the association of peripheral eosinophil (EOS) count with disease activity and kidney outcomes in lupus nephritis (LN) patients. Methods: A total of 453...

...Gabriel Brayan Gutiérrez-Peredo; Iris Montaño-Castellón; Andrea Jimena Gutiérrez-Peredo; Juan P Aguilar Ticona; Fabio Montaño-Castellón; José César Batista Oliveira Filho; Antonio Raimundo Pinto Almeida Background: Lupus nephritis (LN) occurs in approximately 50% of people with systemic lupus...

...Enrique Morales; Maria Galindo; Hernando Trujillo; Manuel Praga Lupus nephritis (LN) is one of the most common manifestations of systemic lupus erythematosus (SLE), affecting approximately 40% of patients with lupus. It represents a major risk factor for morbidity and mortality, and 10% of patients...

...Camila Oliveira; Henrique Mariz; Gisele Fernandes; Denise Costa; Maria Alina Cavalcante; Lucila Valente Introduction: The International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification of lupus nephritis (LN) divides class IV into segmental and global (IV-S and IV-G) based...

... this glomerulopathy and polymorphisms of the MBL2 gene, which is responsible for producing MBL [ 15-18 ]. Although lupus nephritis is associated with genetic variants of MBL2 and the consequent deficient production of the MBL protein [ 19, 20 ], only Bally et al. [ 21 ] have evaluated the sequencing of the MBL2...

...Rubina Novelli; Elena Gagliardini; Barbara Ruggiero; Ariela Benigni; Giuseppe Remuzzi Background/Aims: Lupus nephritis (LN) is a frequent complication and a major predictor of poor prognosis of systemic lupus erythematosus. Immune complex deposition and T cell infiltration are crucial events in LN...

... and in diabetic patients [ 9 ], as well as in hypertensive patients with chronic kidney disease [ 24 ]. Of note, in patients suffering from systemic lupus erythematosus, serum Sema3A levels have been reported to inversely correlate with disease activity and the presence of lupus nephritis [ 25 ]. The potential...

...Jyh Seng Wang; Hui Hwa Tseng; Deng Fuh Shih; Huei Shu Jou; Luo Ping Ger To understand the expression of inducible nitric oxide synthase (iNOS) and its possible association with apoptosis in human lupus nephritis, 48 renal tissue samples from patients with lupus nephritis were investigated...

... formation in murine lupus nephritis. 24 01 1997 23 12 2008 © 1997 S. Karger AG, Basel 1997 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means...

...Tak-Mao Chan; Fu-Keung Li; Raymond W.S. Wong; Kee-Lam Wong; Kwok-Wah Chan; Ignatius K.P. Cheng A retrospective single-center cohort study was conducted on 35 patients with diffuse proliferative (WHO type IV) and/or membranous (type V) lupus nephritis (22 with type IV, 6 with type V, and 7 with type...

...Chika Entani; Kiyoshi Izumino; Hiroyuki Iida; Masuo Fujita; Mitsuhiro Asaka; Masanobu Takata; Shigetake Sasayama We evaluated the effect of the novel immunosuppressive agent, FK506, which is known to inhibit T cell immunity, on the development of lupus nephritis in MRL/MpJ-lpr/lpr (MRL/l) mice...

..., instructions or products referred to in the content or advertisements. Plasma fibronectin Renal fibronectin Chronic glomerulonephritis Lupus nephritis /. Altunkovaa V. Minkovab N. Belovezhdova Departments of a Internal Medicine and b Pathology, Medical Academy, Sofia, Bulgaria Original Paper...

...Gerardo Gamba; Edgardo Reyes; Arturo Angeles; Leticia Quintanilla; Juan Calva; José Carlos Peña The present study was designed to evaluate the observer reliability in the scoring of the activity and chronicity indexes, among three experienced pathologists, in renal biopsies from lupus nephritis (LN...

...Hirohide Ito; Ryuji Harada; Yoshio Uchida; Kazuaki Odashiro; Kimiharu Uozumi; Yuichiro Yasumoto; Tamotsu Ohashi; Wataru Yamashita; Toshiaki Uematsu; Shuichi Hanada; Terukatsu Arima; Yasumasa Tanoue A 64-year-old Japanese male patient with lupus nephritis associated with adult T cell leukemia (ATL...

...Ching-Yuang Lin From January 1986 to December 1988, 8 patients with lupus nephritis did not respond to the administration of two courses of methylprednisolone pulse therapy and cyclophosphamide treatment for 56 days. These cases then received intravenous prostaglandin E 1 (PGE 1 ) for 3 weeks. All...

...Ching-Yuang Lin; Hey-Chi Hsu; Hung Chiang From July 1984 to December 1987,9 patients with lupus nephritis did not respond to the administration of two courses of methylprednisolone pulse therapy and cyclophosphamide treatment for 56 days. Therefore, high-dose intravenous human γ-globulin (IVIG...

...M.H. Park; V. D’Agati; G.B. Appel; C.L. Pirani The interrelationships between tubulointerstitial immune deposits (TID), interstitial inflammation, glomerular changes, renal function, and prognosis were assessed in the renal biopsies from 93 patients with lupus nephritis. The prevalence of TID...