...Maša Skelin Klemen; Jan Kopecky; Jurij Dolenšek; Andraž Stožer Background: Beta cells play a key role in the pathophysiology of diabetes since their functional adaptation is able to maintain euglycemia in the face of insulin resistance, and beta cell decompensation or dysfunction is a necessary...

..., hs-CRP, and insulin resistance were characteristic features in pruritic patients ( p = 0.01, 0.006, 0.0001, 0.047, 0.01, 0.0001, 0.024, 0.000, and 0.0001, respectively). Significant positive correlations were found between pruritus score and each of age ( p = 0.002, r = 0.222), duration of dialysis...

... patients [ 11,24 ]. Circulating AGE levels fall significantly following successful kidney transplantation [ 25 ]. Advanced glycation end products Carboxymethyllysine CKD Diabetes Endothelial dysfunction Inflammation Insulin resistance Oxidative stress Nutrition A large body...

... Glucose intolerance has been shown in patients with chronic renal failure (CRF), probably associated with insulin resistance in peripheral tissues. The present study was thus designed to investigate the effect of hemodialysis on peripheral muscle glucose metabolism of patients with CRF. Nine...

...R. Dzúrik; V. Spustová; K. Janeková Patients with advanced renal failure suffer from almost constant insulin resistance (IR) which is a major risk factor of atherosclerosis and very probably also of glomemlosclerosis. However, data on IR in kidney disease patients with mild-to-moderate kidney...

...) area and C-peptide (C-p) area response, insulinogenic index (IGI) and insulin resistance index (RI) were calculated. Compared to controls, all uremic groups showed significantly lower values of K and IGI and significantly higher values of C-p area and RI. In group C, RI was significantly higher than...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Insulin Insulin receptor Insulin resistance Tyrosine kinase Pyruvate dehydrogenase Uremia Experimental uremia...

...José R. Weisinger; Nelson E.I.R. Contreras; Jorge Cajias; Ezequiel Bellorin-Font; Pablo Amair; Luis Gutierrez; Victoria Sylva; Virgilio Paz-Martínez Insulin resistance in uremia has been attributed to impaired hormone-receptor binding or to postbinding defects. Oral glucose tolerance tests, insulin...

...Masao Kanauchi; Yasuhiro Akai; Toshio Hashimoto Background/Aims: Insulin resistance and hyperinsulinemia has been reported in patients with chronic renal failure. However, usefulness and validation of new indices for assessment to insulin sensitivity and pancreatic beta-cell function were unknown...

...Kazuyoshi Okada; Yoshiko Takahashi; Erina Okawa; Yoshihiko Onishi; Chihiro Hagi; Kyoko Aoki; Hiroshi Shibahara; Terumi Higuchi; Yuji Nagura; Katsuo Kanmatsuse; Susumu Takahashi The relationship between insulin resistance and local uremic toxins was examined using an oral adsorbent. Fourteen rats...

... patients, and it is attributed either to uraemic toxins or to anaemia or even to secondary hyperparathyroidism. Considering the conflicting data of few existing studies, we examined the influence of erythropoietin (EPO) treatment on insulin resistance and tested the probable correlation of this influence...