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Keywords: Inflammation
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Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (12): 733–736.
Published Online: 13 September 2023
..., instructions or products referred to in the content or advertisements. 2023 Sepsis Inflammation Critical illness Nutrition Metabolism Fasting metabolism Glucose metabolism Proteolysis NIH Despite the availability of broad-spectrum antibiotics and life-supporting technologies...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (9): 560–571.
Published Online: 05 June 2023
... Sosa; Manuel Macia; Elena Terán García; Alejandra Álvarez González; Ana González Rinne; Aurelio Rodríguez; Eduardo De Bonis Redondo; Concepción Rodríguez Adanero; Domingo Hernández; Armando Torres Ramírez; Esteban Porrini Introduction: Inflammation is a risk factor for diabetes in the general...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (11): 693–700.
Published Online: 01 June 2023
...Daniel Landau; Nehoray Shukri; Eden Arazi; Ana Tobar; Yael Segev Introduction: Low-grade inflammation is seen in many chronic illnesses, including chronic kidney disease (CKD). We have recently reported on beneficiary effects of anti-inflammatory treatment in the interleukin (IL-) 1 pathway...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (2): 108–119.
Published Online: 21 March 2023
... assay verified Nrf2 as a direct target of miR-155-5p. Our further results indicated anti-miR-155-5p could suppress kidney oxidative stress and inflammation, also supporting Nrf2 was the direct target of miR-155-5p. Finally, we also found miR-155-5p did not increase in serum but significantly increased...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (1): 3–5.
Published Online: 14 February 2023
... of inflammatory and apoptotic pathways in the pathogenesis of cisplatin-induced AKI prompts the use of natural anti-inflammatory compounds. In this context, resolution of inflammation using natural antioxidant and anti-inflammatory such as urolithin A (UA) could prove beneficial. In the end, testing...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (1): 17–20.
Published Online: 14 February 2023
.... This pattern is consistent with complement activation and uncontrolled inflammation, two features of endotoxemia. Unbiased discovery using artificial intelligence also identifies a subtype of sepsis which features these same organ failures. Conclusion: Endotoxin appears to represent an important molecular...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (1): 25–30.
Published Online: 14 February 2023
...://doi.org/10.1016/j.kint.2015.11.019 . 3. Jang HR , Gandolfo MT , Ko GJ , Satpute S , Racusen L , Rabb H . Early exposure to germs modifies kidney damage and inflammation after experimental ischemia-reperfusion injury . Am J Physiol Renal Physiol...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2023) 147 (1): 39–43.
Published Online: 14 February 2023
... analysis of M1 and M2 signatures to identify markers that may better correspond to macrophage functional states. Resident macrophages Inflammation Acute renal failure CKD Acute kidney injury NIH The innate response to kidney injury is a complex reaction that involves...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2022) 146 (3): 264–267.
Published Online: 25 August 2021
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute renal injury CKD Inflammation National Institutes of Health (NIH) 10.13039/100000002 Acute...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2021) 145 (5): 553–567.
Published Online: 14 June 2021
.... CaD may exert its protective effect through alleviating oxidative stress, apoptosis, and inflammation, as well as modulating some signaling pathways in the kidney. 10 10 2020 24 02 2021 14 6 2021 The fixed kidney (left one) samples were embedded in paraffin and then sectioned...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2020) 144 (12): 626–628.
Published Online: 13 July 2020
...Rahul Sharma Acute kidney injury (AKI) affects 20–50% of hospitalized and intensive care patients, with a sizable proportion progressing to ESRD or death ( https://www.kidney.org/atoz/content/AcuteKidneyInjury ). Since inflammation contributes to the pathogenesis of AKI, studies on T-regulatory...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2019) 143 (3): 166–169.
Published Online: 09 July 2019
... inflammation and prevent ischemia-induced AKI can have translational potential in humans. For example, one can pre-emptively infuse IgM or ex vivo induced Bregs in patients who have a high risk of developing ischemia-induced AKI, especially the subset of these patients with low levels of IgM-ALA or regulatory...
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2019) 142 (3): 208–215.
Published Online: 28 March 2019
... with concomitant proteinuria were at the highest risk (4.01 [1.71–8.33], p = 0.0001). Conclusions: In patients with hematuric NHL, systemic inflammation is likely to develop to such a great extent that kidney damage occurs. Therefore, the presence of hematuria, alone or especially in combination with proteinuria...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2019) 143 (1): 12–16.
Published Online: 01 October 2018
... the immune response and inflammation appear to be relevant factors. Summary: This review summarizes the role of relevant inflammatory molecules and pathways that participate in the development of DKD. Likewise, we focused on the new therapeutic approaches based on anti-inflammatory effects of different drugs...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Journal: Nephron
Nephron (2018) 140 (2): 148–151.
Published Online: 06 July 2018
... filtration rate. EA-230, a linear tetrapeptide (Alanine-Glutamine-Glycine-Valine), derived from the β-chain of the human chorionic gonadotropin hormone, has shown immunomodulatory and renoprotective properties in several pre-clinical animal models of systemic inflammation. Furthermore, an excellent safety...