... inflammation, particularly disregarding those inflammatory infiltrates who do not reach the category of rejection. Summary: The term subclinical inflammation was introduced to designate the inflammation found in protocol biopsies, without significant renal function deterioration. Following the introduction...

... reporter assays demonstrated that SOCS3 is a direct target of miR-455-5p. Conclusion: This study indicates an NF-κB/miR-455-5p/SOCS3 axis which can exacerbate kidney damage by enhancing renal inflammation. This process highlights potential therapeutic targets for managing septic AKI. [email protected]...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Cystinuria Nephrolithiasis Immunology Proximal tubule Atopia Inflammation Cystinuria (CYS) is a rare genetic disorder involving the transport of dibasic...

..., instructions or products referred to in the content or advertisements. 2023 Sepsis Inflammation Critical illness Nutrition Metabolism Fasting metabolism Glucose metabolism Proteolysis NIH Despite the availability of broad-spectrum antibiotics and life-supporting technologies...

...Zihao Zhang; Peipei Liu; Ling Yang; Naihui Zhao; Wenli Ou; Xiaofu Zhang; Yinggen Zhang; Shuohua Chen; Shouling Wu; Xiuhong Yang Introduction: Inflammation is associated with development of chronic kidney disease (CKD). However, the association of the high-sensitivity C-reactive protein (hs-CRP...

..., instructions or products referred to in the content or advertisements. 2023 Acute kidney injury Selective cytopheretic device Kidney Immunomodulation Inflammation Leukocyte Continuous kidney replacement therapy Selective cytopheretic device Neutrophils Monocytes Hyperinflammation Cytokine...

... Sosa; Manuel Macia; Elena Terán García; Alejandra Álvarez González; Ana González Rinne; Aurelio Rodríguez; Eduardo De Bonis Redondo; Concepción Rodríguez Adanero; Domingo Hernández; Armando Torres Ramírez; Esteban Porrini Introduction: Inflammation is a risk factor for diabetes in the general...

...Daniel Landau; Nehoray Shukri; Eden Arazi; Ana Tobar; Yael Segev Introduction: Low-grade inflammation is seen in many chronic illnesses, including chronic kidney disease (CKD). We have recently reported on beneficiary effects of anti-inflammatory treatment in the interleukin (IL-) 1 pathway...

... assay verified Nrf2 as a direct target of miR-155-5p. Our further results indicated anti-miR-155-5p could suppress kidney oxidative stress and inflammation, also supporting Nrf2 was the direct target of miR-155-5p. Finally, we also found miR-155-5p did not increase in serum but significantly increased...

... of inflammatory and apoptotic pathways in the pathogenesis of cisplatin-induced AKI prompts the use of natural anti-inflammatory compounds. In this context, resolution of inflammation using natural antioxidant and anti-inflammatory such as urolithin A (UA) could prove beneficial. In the end, testing...

... composition plays a vital role in maintaining intestinal homeostasis and immune system function. An imbalance in the gut microbiota (gut dysbiosis) has been associated with disruption in the intestinal mucosal barrier and activation of immune system-mediated inflammation in various diseases including kidney...

... treatment, which should deplete DC but not macrophages, prevented the increase in plasma creatinine [ 10 ], further indicating ischemic injury is not mediated by resident macrophages (Fig.  1 ). Resident macrophages Inflammation Acute renal failure CKD Acute kidney injury References 1...

.... This pattern is consistent with complement activation and uncontrolled inflammation, two features of endotoxemia. Unbiased discovery using artificial intelligence also identifies a subtype of sepsis which features these same organ failures. Conclusion: Endotoxin appears to represent an important molecular...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute renal injury CKD Inflammation National Institutes of Health (NIH) 10.13039/100000002 Acute...

.... CaD may exert its protective effect through alleviating oxidative stress, apoptosis, and inflammation, as well as modulating some signaling pathways in the kidney. Burn Acute kidney injury Calcium dobesilate Reactive oxygen species Inflammation Oxidative stress Severe trauma...

...Rahul Sharma Acute kidney injury (AKI) affects 20–50% of hospitalized and intensive care patients, with a sizable proportion progressing to ESRD or death ( https://www.kidney.org/atoz/content/AcuteKidneyInjury ). Since inflammation contributes to the pathogenesis of AKI, studies on T-regulatory...

... and water retention and disturbances in the macro-and microcirculation. Objectives: We hypothesize that salt and water dysregulation in advanced CKD may be linked to inflammation and microvascular injury pathways. Methods: We studied 23 CKD stage 5 patients and 11 healthy controls (HC). Tissue sodium...

... inflammation and prevent ischemia-induced AKI can have translational potential in humans. For example, one can pre-emptively infuse IgM or ex vivo induced Bregs in patients who have a high risk of developing ischemia-induced AKI, especially the subset of these patients with low levels of IgM-ALA or regulatory...

... with concomitant proteinuria were at the highest risk (4.01 [1.71–8.33], p = 0.0001). Conclusions: In patients with hematuric NHL, systemic inflammation is likely to develop to such a great extent that kidney damage occurs. Therefore, the presence of hematuria, alone or especially in combination with proteinuria...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hemodialysis patients Inflammation Nutrition Malnutrition...