...Claudine Orfila; Jean-Claude Lepert; Anne Modesto; Bernard Pipy; Jean-Michel Suc A 17-year-old man presented Henoch-Schönlein purpura with renal impairment, nephrotic syndrome needing transitory hemodialysis and hematuria. By light microscopy, the renal biopsy revealed membranoproliferative-like...

... index of activity on renal biopsy in patients with severe forms of IgA nephropathy (IGAN) and Henoch-Schönlein purpura (HSP). The aim of this open prospective trial was to evaluate the efficacy and safety of low-dose immunoglobulin therapy in moderate IGAN and HSP with permanent proteinuria. Fourteen...

...Jesús Montoliu; Xosé M. Lens; Albert Torras; Lluís Revert Considerable controversy exists as to whether Henoch-Schönlein purpura and Iga nephropathy are different clinical manifestations of the same disease or if, on the contrary, they are separate entities. We report on the development of Henoch...

... describe presented with severe Henoch-Schönlein purpura (HSP) at the age of 17. Immunofluorescence of a kidney biopsy showed granular deposits of IgG, IgA, IgM, C3 and fibrinogen in the mesangium and segmentally along the basement membrane. Six years later, the patient developed hypertension and nephrotic...

...B. Casanueva; V. Rodriguez-Valverde; M.C. Fariñas; A. Valio; J. Rodriguez-Soriano To assess the existence of persistent abnormalities in the cellular mechanisms regulating the immunoglobulin (Ig) synthesis in Henoch-Schönlein purpura (HSP) and IgA nephropathy, we studied through a hemolityc plaque...

...Ronald J. Hené; Henk-Jan Schuurman; Louis Kater We studied the distribution of IgAl- and IgA2-containing plasma cells in the jejunum of 5 patients with primary IgA nephropathy and of 2 patients with Henoch-Schönlein purpura. The percentage of IgA-containing cells (62.3. ± 4.6) was below the level...

...John H. Galla Evidence from both genotypic and phenotypic perspectives is considered that patients may be genetically predisposed to IgA nephropathy (IgAN) or Henoch-Schönlein purpura (HSP) or that a factor(s) might exclusively contribute to their progression to chronic renal failure. In contrast...