...Min Luo; Zongren Hu; Jichang Yang; Jinhan Yang; Wen Sheng; Chengxiong Lin; Dian Li; Qinghu He Background: The progression of diabetic nephropathy (DN) is closely associated with lipid accumulation. Diosgenin (Dio) plays a beneficial role in the lipid metabolism associated with multiple diseases...

... and impaired renal function (eGFR <60 mL/min/1.73 m 2 [eGFR <60]) in type 2 diabetic patients with early diabetic nephropathy. Methods: The study population consisted of 35 patients with type 2 diabetes (25 men; age: 47 ± 9 years; eGFR: 92.7 ± 18.0 mL/min/1.73 m 2 ) with normo- or microalbuminuria who...

... with the aim of improving access to human DKD tissue for research purposes. For example, the Transformative Research in Diabetic Nephropathy (TRIDENT) consortium is coordinating the collection of kidney tissue from patients with DKD undergoing clinically indicated kidney biopsies across multiple centres...

...Fen Feng; Jie Yang; Gang Wang; Ping Huang; Yongjie Li; Bin Zhou Background: Many studies have confirmed that circular RNA (circRNA) is an important target for regulating human disease progression. This study aimed to explore the role of circ_0068087 in diabetic nephropathy (DN) progression. Methods...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Piceatannol High glucose Diabetic nephropathy Carbonic anhydrase 2 As a severe complication of diabetes characterized by increased permeability...

...Dan Liu; Ruoxin Chen; Haifeng Ni; Hong Liu Introduction: Recent studies have elucidated that miR-181a plays a vital role in various inflammation-associated diseases; however, its role in the pathogenesis of diabetic nephropathy (DN) has not been elucidated clearly. Hence, we investigated...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Diabetic nephropathy Glomerulosclerosis Dialysis Translational research Systematic review Deutsche...

...Qunjuan Lei; Feng Xu; Shaoshan Liang; Dandan Liang; Jingru Lu; Rong Tang; Xianguang Zhou; Zhihong Liu; Caihong Zeng Introduction: Histologic acute tubular-interstitial injury (hATI) is often observed in patients with diabetic nephropathy (DN). This study aimed to determine the relationship between...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Peritoneal dialysis Diabetic nephropathy Hemoglobin A1c Fructosamine Continuous glucose monitoring...

...Yuan Zhang; Xiaolan Chen; Yaping Fan; Jing Liu; Li Yuan Background: Glomerular endothelial cell damage plays an important role in the occurrence and development of diabetic nephropathy (DN). Objectives: This study aimed to clarify the role of XCL1 in DN-mediated glomerular endothelial cell...

...Jing Wang; Shifeng Yang; Wendong Li; Ming Zhao; Kai Li Background: Diabetic nephropathy (DN) is a severe microvascular complication of diabetes. Recently, many circular RNAs can exert crucial roles in DN progression. This study intended to explore the role and mechanism of circ_0000491 in DN...

..., instructions or products referred to in the content or advertisements. Visual Abstract Visual Abstract. Macrophages Diabetic nephropathy Transcriptome sequencing MAPK pathway Diabetic nephropathy (DN), a prevalent chronic kidney disease, is the leading cause of end-stage renal...

... on the role of some of the best-characterized lncRNAs implicated in the pathogenesis and progression of diabetic nephropathy. [email protected] 27 09 2020 19 02 2021 14 4 2021 Importantly, a number of online databases have been created to study the structure and function...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Liraglutide Type 2 diabetes Chronic hemodialysis Diabetic nephropathy Peritoneal dialysis Diabetic kidney disease is the leading cause...

.... Taurine Diabetic nephropathy Mitochondria Podocytes TRPC6 Oxidative stress Diabetic kidney disease (DKD) is one of the most serious complications of diabetes and has been considered to be the leading cause of end-stage renal disease in the world [ 1, 2 ]. Currently, the injury of podocytes...

...Mamdouh A. Oraby; Mohammed F. El-Yamany; Marwa M. Safar; Naglaa Assaf; Hamdy A. Ghoneim Background: Early prediction and clinical intervention are extremely important in order to delay or hinder diabetic nephropathy (DN) progression. Objectives: This study aimed to detect early signs of DN...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Diabetic nephropathy 12-Lipoxygenase Angiotensin II p21 p27 Renal hypertrophy, an early manifestation...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cysteine-S-conjugates Diabetic nephropathy...

...Christian Albert; Johanna Kube; Annemarie Albert; Denny Schanze; Martin Zenker; Peter R. Mertens Aim: Aim of this study was to investigate the association of genetic variants of functional polymorphisms of matrix metalloproteinase and Cubilin (CUBN) with diabetic nephropathy (DN), end-stage renal...

...Georgia E. Fouli; Luigi Gnudi Diabetic nephropathy is the commonest cause of end-stage renal disease and affects between 30 and 45% of patients with diabetes mellitus. There is no cure for diabetic nephropathy and the current management of this condition includes glycaemic control, blockade...