... on anemia as well as CKD extent in a mouse model. Colchicine has been shown to have beneficiary effects in several inflammatory conditions through various mechanisms, including inhibition of tubulin polymerization as well as caspase-1-mediated IL-1 activation. Methods: Kidney injury (KI) was induced...

... treatment was either antischistosomal alone, combined anti-schistosomal and colchicine, or colchicine alone. Eighteen weeks after infection half of the animals in each group were sacrificed, while the rest were sacrificed 24 weeks after infection. Kidney specimens were evaluated semiquantitatively for renal...

...Avi Livneh; Deborah Zemer; Bruno Siegal; Arie Laor; Ezra Sohar; Mordechai Pras Twenty-one familial Mediterranean fever (FMF) patients who received a kidney transplant for terminal renal failure due to amyloidosis were studied retrospectively to evaluate the prophylactic effect of colchicine...

... of amyloidosis, which was diagnosed by percutaneous kidney biopsies. After the diagnosis of amyloidosis, all subjects received colchicine, and steroids were discontinued. Three patients have benefited from treatment. It was suggested that amyloidosis may be an intrinsic feature of BD or that the suppurative...

...L.S. Milner; D. Lotan; M. Mills; P.R. Goodyer; J.S.C. Fong; B.S. Kaplan Colchicine was given to rats in the heterologous phase of passive Heymann nephritis to see whether this drug could reduce proteinuria. Treatment with 0.06 mg/day for 14 days caused significant reductions in proteinuria...

...Kayser Caglar; Mükerrem Safali; Izzet Yavuz; Zeki Odabaşi; Müjdat Yenicesu; Abdülgaffar Vural A case of a renal transplant recipient with colchicine-induced myopathy is presented. He was on colchicine therapy for 10 months. He was hospitalized for investigation of fatigue, severe myalgia...

...Can Li; Chul Woo Yang; Hee Jong Ahn; Wan Young Kim; Cheol Whee Park; Joo Hyun Park; Jung Ho Cha; Jin Kim; Yong Soo Kim; Byung Kee Bang Background: Colchicine (Col) is beneficial to renal injury because of its anti-inflammatory effect, but its mechanism has yet to be elucidated. The present study...

...Alexander Kagan; Monica Husza’r; Azriel Frumkin; Jayson Rapoport A case of nephrotic syndrome due to AA amyloidosis in a young woman suffering from erythrodermic psoriasis and psoriatic arthropathy is reported. The nephrotic syndrome regressed completely during long-term (57 months) colchicine...

...Mohamed Sobh; Alaa Sabry; Fatma Moustafa; Mohamed A. Foda; Samir Sally; Mohamed Ghoneim Thirty male Sprague-Dawley rats were given ciclosporin (Cs) orally, 15 mg/kg daily for 80 days. Fifteen served as positive controls, while the other 15 were given daily colchicine at a dose of 30 µg/kg...