... of the incident CIN in the ACEI group vs. the control group was 0.95 (95% CI 0.57-1.58), and the total WMDs of the ΔSCr, ΔeGFR and ΔBUN were -0.01 (95% CI -0.04 to 0.02), 5.71 (95% CI -0.66 to 12.09) and 0.78 (95% CI -0.16 to 1.73), respectively. Besides, the RR of CIN incidence in the captopril group vs...

... and a hypoplastic contralateral kidney, a condition comparable to that of the one-kidney Goldblatt hypertension. Both blood volume and plasma renin activity were increased. Blood pressure was lowered either by an angiotensin II analog or by captopril. Secretion of excess renin was observed only from the stenotic...

...Sonoo Mizuiri; Hiromichi Hemmi; Akira Inoue; Masaaki Takano; Satoshi Kadomatsu; Hiroyuki Tanimoto; Masateru Tanegashima; Ikuko Hayashi; Tatsuo Fushimi; Akira Hasegawa We studied the relationship between renal hemodynamic changes induced by a single acute administration of captopril (50 mg p.o...

...V. Kliem; R. Brunkhorst; G. Ehlerding; K. Kühn; K.H. Neumann; K.M. Koch Milan normotensive rats, which spontaneously develop marked proteinuria (PU) and glomerulosclerosis (GS), were either kept on a normal-protein diet, a normal-protein diet with additional low-dose captopril (CAP), which did...

...Mauro Giordano; Leonard R. Sanders; Pietro Castellino; Mitzy L. Canessa; Ralph A. DeFronzo In the present study we investigated the effect of a selective α 1 -adrenergic blocker (doxazosin), an angiotensin-converting enzyme (ACE) inhibitor (captopril), and a calcium channel antagonist (nifedipine...

... 37.1 ± 3, 34 ± 3.5 and 32.6 ± 3.2 at 0, 6 and 12 months, respectively) as well as proteinuria (2.9 ± 1.7, 1.2 ± 1 and 0.4 ± 0.6 g/24 h). There was a significant correlation between body weight loss and decrease in proteinuria (r = 0.69, p < 0.05). Eight patients (group 2) were treated with captopril...

...), 8 renal graft recipients (group 2) and 8 patients after nephrectomy (group 3) werde studied. Furthermore, we investigated the influence of amino acid loading on RAS and ANP and glomerular filtration during acute application of captopril in healthy controls. Clearances in inulin (C In ) and para...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. ACE inhibitors Enalapril Captopril Renal failure 16 12 2008 Nephron 1990;55(suppl I):38-42 0 1990 S. Karger AG. Basel 0028-2766 90...

.... However, the mechanisms of these modifications are still poorly understood. In order to elucidate them we performed maximal exercise tests on 8 untrained healthy volunteers after inhibition of the renin-angiotensin system (RAS) by captopril, the sympathetic nervous system by a β-blocking drug (acebutolol...

... tubulointerstitial chronic abnormalities and focal glomerulosclerosis (FGS) lesions in 24% of the glomeruli. With captopril, an angiotensin-converting enzyme inhibitor, proteinuria showed a clear decrease, but renal function continued to deteriorate. No other cases of nephrotic-range proteinuria were detected among...

... with calcium-blocking agents (diltiazem; CBB) or converting enzyme inhibitors (captopril; CEI) may be indicated to prevent renal failure. We studied the effects of CCB and CEI on the early course of adriamycin (ADR) nephropathy, where glomerular pressure has been shown to be unchanged, blood pressure was only...

...Toshio Ikeda; Daisuke Nakayama; Tomoko Gomi; Jun Sakurai; Tadao Yamazaki; Mikio Yuhara A crossover study was planned in order to compare the effects of captopril and slow channel calcium entry blocker (Ca antagonist) on urinary protein excretion in 7 hypertensive patients with renal diseases...

... it had been low initially, but frequently remained low ( < 45%). The increase of the RHU was significantly higher in patients with a favorable blood pressure response. Pretreatment with captopril did intensify the abnormal curves of hippuran and of DTPA renograms in 6 patients with URAS who did...

...Peter Greminger; Hans Vetter; Johann Steurer; Walter Siegenthaler; Wilhelm Vetter In the present study 25 patients with various forms of severe hypertension (essential hypertension: n = 12; renovascular hypertension: n = 11; unilateral small kidney: n = 2), which were treated with captopril...

...B. Stanek; K. Silberbauer Hemodynamic and hormonal actions of acute (50 mg) and chronic (150 mg/day) captopril were tested in 10 patients with essential hypertension. Under short-term conditions blood pressure was reduced, heart rate and plasma adrenaline did not change, plasma angiotensin II...

... to treat 10 patients with hypertension and diffuse psoriasis with captopril at a dose of 25 mg t.i.d. Five patients had high PRA levels and in 1 of them serum ACE was also increased. Serum creatinine, BUN and urinalysis were normal in all of them. SPB fell from 163 ± 3 to 138 ± 3 and DBP from 107 ± 3 to 86...

...H. Herlitz; C. Edenö; H. Mulec; G. Westberg; M. Aurell Captopril, an angiotensin-converting enzyme inhibitor, was used to treat 14 patients with lupus nephritis and severe hypertension. All patients had reduced renal function and were on regular immunosuppressive therapy with corticosteroids...

...Fokko J. van der Woude; Willem J. van Son; Adam M. Tegzess; Ab J.M. Donker; Maarten J.H. Slooff; Leendert B. van der Slikke; Steven J. Hoorntje We evaluated 9 patients with transplant renal artery stenosis. Captopril treatment always resulted in a dramatic decrease in renal function. Moreover, only...

...Hiroko Suzuki; Masaki Fujimaki; Haruyuki Nakane; Ikuo Saito; Eiko Takeshita; Takao Saruta Captopril (SQ14,225), an orally administered angiotensin converting enzyme inhibitor, was given to 8 patients with idiopathic edema, in order to study the role of the renin-angiotensin-aldosterone system...

...Mattias Aurell; Ava Rudin 3 patients with Bartter’s syndrome were studied under metabolic ward conditions before and during administration of captopril 25 mg t.i.d. The drug induced an immediate and sustained reduction of blood pressure (by 14 and 18% after 1 h and 3 days, respectively...