...Tadao Akizawa; Yusuke Yamaguchi; Tetsuro Otsuka; Michael Reusch Introduction: Roxadustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor approved for the treatment of anemia in Japan for patients with dialysis-dependent (DD) chronic kidney disease (CKD). Objective: Multicenter...

...Tadao Akizawa; Iain C. Macdougall; Jeffrey S. Berns; Hiroyasu Yamamoto; Megumi Taguchi; Kazuma Iekushi; Thomas Bernhardt Background/Aims: The current treatment for anemia associated with chronic kidney disease (CKD) includes the administration of erythropoiesis stimulating agents (ESAs) combined...

...Alissa Dratch; Carola-Ellen Kleine; Elani Streja; Melissa Soohoo; Christina Park; Jui-Ting Hsiung; Connie M. Rhee; Yoshitsugu Obi; Miklos Z. Molnar; Csaba P. Kovesdy; Kamyar Kalantar-Zadeh Background/Aims: Anemia is common in patients with advanced chronic kidney disease (CKD). A proportion...

...Douglas S. Fuller; Bruce M. Robinson; Francesco Locatelli; Ronald L. Pisoni Background: Clinicians providing dialysis care have numerous erythropoiesis-stimulating agents (ESAs) available for treating anemia. We sought to provide a contemporary description of ESA types used in hemodialysis (HD...

...Sho Sasaki; Hiroo Kawarazaki; Takeshi Hasegawa; Hideaki Shima; Toshihide Naganuma; Yugo Shibagaki Background/Aims: The renal prognosis of post-renal acute kidney injury (PoR-AKI) has not been verified so far. The objective of this study was to assess the association of baseline anemia with long...

...Mauro Boronat; Ángelo Santana; Elvira Bosch; Dionisio Lorenzo; Marta Riaño; César García-Cantón Background/Aims: Different biochemical abnormalities of metabolic bone disease have been associated with anemia of chronic kidney disease (CKD), mainly in hemodialysis patients. However, all...

...Robert C. Albright Jr.; John J. Dillon; Craig L. Hocum; James R. Stubbs; Pamela M. Johnson; LaTonya J. Hickson; Amy W. Williams; David Dingli; James T. McCarthy Background: Anemia management in chronic hemodialysis (HD) has been affected by the implementation of the prospective payment system (PPS...

...Shinji Tanaka; Tetsuhiro Tanaka Iron deficiency is a major cause of hyporesponsiveness to erythropoiesis-stimulating agents (ESAs) and is often observed in chronic kidney disease (CKD) patients with anemia. With iron supplementation, ESA doses can be decreased, resulting in lower treatment costs...

...; baseline vs. 2 vs. 4 h, respectively). Our data suggest that the absorption of both ferrous sulfate and ferric polysaccharide complex is poor in patients on CAPD. Iron Niferex® Erythropoietin Anemia Continuous ambulatory peritoneal dialysis NEPHRON Original Paper Nephron 1996;74:291-294 Mohammad...

...Toshihiko Ishimitsu; Hidehiko Ono; Mutsumi Sugiyama; Hiroshi Asakawa; Kazuo Oka; Atsushi Numabe; Minoru Abe; Hiroaki Matsuoka; Shigeru Yagi A 62-year-old woman presented with nephrotic syndrome and severe anemia although the renal function was not impaired. Renal biopsy revealed the histology...

... erythropoietin Anemia Hemoglobin Erythropoiesis Kidney transplantation NEPHRON Original Paper Nephron 1996:74:687-693 Janusz Gocha Gunnar Birgegärdb Björn W ikströma Ulla Backinan3 Jonas Wadströmc Bo G. Danielsona a Department ol'InternalMedicine, Renal Unit and b Hematology Unit and c Department...

...Onyekachi Ifudu; Mohammed Dawood; Eli A. Friedman Anemia in chronic renal failure is predominantly caused by diminished erythropoietin synthesis by diseased kidneys. While iron deficiency is often stated as a cause of anemia in chronic renal failure prior to end-stage renal disease, its relative...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Iron absorption Anemia Uremia Hemodialysis NEPHRON Original Paper...

...F. Zhang; R.F. Gagnon; G.K. Richards; A.G. Brox Anemia is a cardinal feature of chronic renal failure (CRF) which contributes significantly to the clinical syndrome of chronic uremia. We have conducted a detailed examination of the hematological changes in CRF in the inbred mouse strain C57BL/6J...

... 2008 Erythropoietin Hypocalcemia Furosemide Acetazolamide Enalapril Uremic patients Hemodialysis Anemia © 1995 S. Karger AG, Basel 1995 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages...

... muscle metabolic rate in hemodialysis patients, and that the anemia per se seems to be an important cause of the deranged metabolism in striated muscle. 30 06 1993 17 12 2008 © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... to in the content or advertisements. Hemodialysis Anemia Ferritin Mean corpuscular volume Original Paper Nephron 1994;67:30-35 P. Goldw dsser T. Koutelos S. Abraham M . M . Avram Division of Nephrology, The Avram Center for Kidney Disease, The Long Island College Hospital. Brooklyn, N .Y., USA Serum...

...P. Brunet; Y. Berland; T. Merzouk; D. Vanuxem; M. Badier; H. Klinkmann; A. Crevat Anemia of chronic renal failure is associated with a reduced affinity of hemoglobin for oxygen (Hb-O 2 affinity). It has been reported that the correction of renal anemia by recombinant human erythropoietin (rhuEPO...

... (489 vs. 362 s, p ± 0.01). ST segment depression during maximal exercise was reduced from a mean of 2.1 to 0.4 mm (p < 0.01). It is concluded that amelioration of renal anemia by erythropoietin in dialysis patients with significant coronary artery disease reduces exercise-induced myocardial ischemia...

...) and 85 ± 14.01 μg/dl (p < 0.01), respectively. TIBC and ferritin did not change but the transferrin saturation index increased significantly. DFO produces an immediate improvement of the anemia in HD patients treated with rHuEPO and who have minimal aluminium accumulation: it should be related...