1α,25-Dihydroxyvitamin D3, the hormonal form of vitamin D3, is widely appreciated to play a central role in calcium and phosphorous homeostasis. It is becoming increasingly clear, however, that the sterol also plays an important role in the regulation of cellular growth, central nervous system function, and immune responsiveness. In this review, I will highlight some of the mechanisms by which 1α,25-dihydroxyvitamin D3 regulates cellular growth, alters central nervous system function, and immune function.

Keywords:
Vitamin D, 1α,25(OH)2D3, Growth factors, Immune function
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