This is a case report of Waldenström’s macroglobulinemia associated with mesangio-capillary glomerulonephritis, angiitis and myositis. The renal lesion was a major problem. The confinement of lymphadenopathy to the abdominal cavity with absence of an M component in the serum electrophoretic pattern hindered precise antemortem diagnosis. The accompanying mild increase in serum IgA mimicked Aleutian mink disease. The possibility of dysproteinemia playing a role in the renal alteration is suggested. We believe that the primary disease is dysproteinemia with an immune disturbance in a lymphoproliferative disorder with diversified clinical manifestations.

Keywords:
Waldenström’s macroglobulinemia, Mesangio-capillary glomerulonephritis, Myositis, Angiitis
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© 1973 S. Karger AG, Basel
1973
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