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Keywords: p21
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Journal Articles
Subject Area:
Nephrology
Toshiaki Monkawa, Jeffrey Pippin, Yoshikage Yo, Jeffrey B. Kopp, Charles E. Alpers, Stuart J. Shankland
Journal:
Nephron Experimental Nephrology
Nephron Experimental Nephrology (2006) 102 (1): e8–e18.
Published Online: 22 September 2005
.... Proliferation and apoptosis are controlled by specific cell cycle proteins, where cyclin-dependent kinase (CDK) inhibitors such as p21 bind target cyclin-CDK complexes. However, the role of p21 in acute mesangial proliferative GN is not known. This study was conducted to test the hypothesis that p21 regulates...