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Keywords: Transforming growth factor-beta
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Journal Articles

Gremlin Is a Downstream Profibrotic Mediator of Transforming Growth Factor-Beta in Cultured Renal Cells

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Subject Area:
Nephrology
Raquel Rodrigues-Diez, Carolina Lavoz, Gisselle Carvajal, Sandra Rayego-Mateos, Raul R. Rodrigues Diez, Alberto Ortiz, Jesús Egido, Sergio Mezzano, Marta Ruiz-Ortega
Journal: Nephron Experimental Nephrology
Nephron Experimental Nephrology (2012) 122 (1-2): 62–74.
https://doi.org/10.1159/000346575
Published Online: 14 March 2013
... profibrotic events in cul-tured renal fibroblasts and tubular epithelial cells. Moreover, endogenous Gremlin blockade inhibited TGF-β-mediated matrix production and EMT, suggesting that Gremlin could be a novel therapeutic target for renal fibrosis. Gremlin Transforming growth factor-beta Renal fibrosis...
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Journal Articles

Protein Restriction Ameliorates Renal Tubulointerstitial Nephritis and Reduces Renal Transforming Growth Factor-Beta Expression in Unilateral Ureteral Obstruction

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Subject Area:
Nephrology
Ko Sawashima, Shinya Mizuno, Yoko Mizuno-Horikawa, Tadaaki Kudo, Tsutomu Kurosawa
Journal: Nephron Experimental Nephrology
Experimental Nephrology (2002) 10 (1): 7–18.
https://doi.org/10.1159/000049893
Published Online: 09 January 2002
..., instructions or products referred to in the content or advertisements. Mice Protein restriction Transforming growth factor-beta Tubulointerstitial fibrosis Unilateral ureteral obstruction Numerous studies have suggested that the renoprotective effect of a low-protein diet be related to its...
View articletitled, Protein Restriction Ameliorates Renal Tubulointerstitial Nephritis and Reduces Renal Transforming Growth Factor-Beta Expression in Unilateral Ureteral Obstruction
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